Mechanotransduction in the Endothelium: Role of Membrane Proteins and Reactive Oxygen Species in Sensing, Transduction, and Transmission of the Signal with Altered Blood Flow

Properties of Mechano-Transduction via Simulated Microgravity and its Effects on Intracellular Trafficking of VEGFR’s

(2015) Andrew Puca et al.   Oncotarget

S-Glutathionylation of Ion Channels: Insights into the Regulation of Channel Functions, Thiol Modification Crosstalk, and Mechanosensing

(2013) Yang Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

Mechanical Stretch-Induced Activation of ROS/RNS Signaling in Striated Muscle

(2013) Christopher W. Ward et al.   ANTIOXIDANTS & REDOX SIGNALING

Mechanotransduction Drives Post Ischemic Revascularization Through KATP Channel Closure and Production of Reactive Oxygen Species

(2013) Elizabeth Browning et al.   ANTIOXIDANTS & REDOX SIGNALING

Nox Family NADPH Oxidases in Mechano-Transduction: Mechanisms and Consequences

(2013) Ralf P. Brandes et al.   ANTIOXIDANTS & REDOX SIGNALING

Hemodynamic Regulation of Reactive Oxygen Species: Implications for Vascular Diseases

(2013) Uwe Raaz et al.   ANTIOXIDANTS & REDOX SIGNALING

The Purified Mechanosensitive Channel TREK-1 Is Directly Sensitive to Membrane Tension

(2013) Catherine Berrier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanical Properties of β-Catenin Revealed by Single-Molecule Experiments

(2012) Alejandro Valbuena et al.   BIOPHYSICAL JOURNAL

Calcium signaling in the cochlea – Molecular mechanisms and physiopathological implications

(2012) Federico Ceriani et al.   Cell Communication and Signaling

Interleukin 6 augments mechanical strain-induced C-reactive protein synthesis via the stretch-activated channel–nuclear factor κ B signal pathway

(2012) Huaineng Zhou et al.   HEART

Signalling through mechanical inputs – a coordinated process

(2012) Huimin Zhang et al.   JOURNAL OF CELL SCIENCE

Mechanosensitive mechanisms in transcriptional regulation

(2012) Akiko Mammoto et al.   JOURNAL OF CELL SCIENCE

Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress

(2012) Kate M. Herum et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A multichannel dampened flow system for studies on shear stress-mediated mechanotransduction

(2012) Peter L. Voyvodic et al.   LAB ON A CHIP

Mechanism for Effective Lymphoid Cell and Tissue Loading Following Oral Administration of Nucleotide Prodrug GS-7340

(2012) Darius Babusis et al.   MOLECULAR PHARMACEUTICS

Involvement of large conductance Ca2+-activated K+ channel in laminar shear stress-induced inhibition of vascular smooth muscle cell proliferation

(2012) Xiaoling Jia et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Focal Adhesion Kinase Plays a Role in Osteoblast Mechanotransduction In Vitro but Does Not Affect Load-Induced Bone Formation In Vivo

(2012) Alesha B. Castillo et al.   PLoS One

Microtubules Underlie Dysfunction in Duchenne Muscular Dystrophy

(2012) R. J. Khairallah et al.   Science Signaling

Wall Shear Stress is Decreased in the Pulmonary Arteries of Patients with Pulmonary Arterial Hypertension: An Image-Based, Computational Fluid Dynamics Study

(2012) Beverly T. Tang et al.   Pulmonary Circulation

Stop the Flow: A Paradigm for Cell Signaling Mediated by Reactive Oxygen Species in the Pulmonary Endothelium

(2011) Elizabeth A. Browning et al.   Annual Review of Physiology

Disturbed-Flow-Mediated Vascular Reactive Oxygen Species Induce Endothelial Dysfunction

(2011) Kyung-Sun Heo et al.   CIRCULATION JOURNAL

Peroxiredoxin 6 Phosphorylation and Subsequent Phospholipase A2Activity Are Required for Agonist-mediated Activation of NADPH Oxidase in Mouse Pulmonary Microvascular Endothelium and Alveolar Macrophages

(2011) Shampa Chatterjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Basis and Structural Insight of Vascular KATPChannel Gating byS-Glutathionylation

(2011) Yang Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mechanoreceptor TRPV4 is Localized in Adherence Junctions of the Human Bladder Urothelium: A Morphological Study

(2011) Dick A.W. Janssen et al.   JOURNAL OF UROLOGY

Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling

(2011) Victor W Wong et al.   NATURE MEDICINE

X-ROS Signaling: Rapid Mechano-Chemo Transduction in Heart

(2011) B. L. Prosser et al.   SCIENCE

Imaging Leukocyte Adhesion to the Vascular Endothelium at High Intraluminal Pressure

(2011) Danielle L. Michell et al.   Jove-Journal of Visualized Experiments

Regulation of blood flow in the microcirculation: role of conducted vasodilation

(2010) P. Bagher et al.   Acta Physiologica

Endothelial Atheroprotective and Anti-inflammatory Mechanisms

(2010) BRADFORD C. BERK et al.   Annals of the New York Academy of Sciences

Role of PECAM-1 in Arteriogenesis and Specification of Preexisting Collaterals

(2010) Zhongming Chen et al.   CIRCULATION RESEARCH

Interfering with the connection between the nucleus and the cytoskeleton affects nuclear rotation, mechanotransduction and myogenesis

(2010) Michaela Brosig et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Oxidative Stress Inhibits Vascular KATPChannels byS-Glutathionylation

(2010) Yang Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The cell biology of touch

(2010) Ellen A. Lumpkin et al.   JOURNAL OF CELL BIOLOGY

Mechanosomes Carry a Loaded Message

(2010) J. P. Bidwell et al.   Science Signaling

Shear stress-induced transcriptional regulation via hybrid promoters as a potential tool for promoting angiogenesis

(2009) Michal Silberman et al.   ANGIOGENESIS

PECAM-1 Is Necessary for Flow-Induced Vascular Remodeling

(2009) Zhongming Chen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of glycocalyx in flow-induced production of nitric oxide and reactive oxygen species

(2009) Robert Kumagai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Endothelial Cell Retention on a Viscoelastic Nanocomposite Vascular Conduit Is Improved by Exposure to Shear Stress Preconditioning Prior to Physiological Flow

(2008) Dina S. Vara et al.   ARTIFICIAL ORGANS

Caveolae are an essential component of the pathway for endothelial cell signaling associated with abrupt reduction of shear stress

(2008) Tatyana Milovanova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Lung Ischemia: A Model for Endothelial Mechanotransduction

(2008) Shampa Chatterjee et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Localized α4 Integrin Phosphorylation Directs Shear Stress–Induced Endothelial Cell Alignment

(2008) Lawrence E. Goldfinger et al.   CIRCULATION RESEARCH

Reactive Oxygen Species-Mediated Pancreatic β-Cell Death Is Regulated by Interactions between Stress-Activated Protein Kinases, p38 and c-Jun N-Terminal Kinase, and Mitogen-Activated Protein Kinase Phosphatases

(2008) Ni Hou et al.   ENDOCRINOLOGY

Mechanotransduction in an extracted cell model: Fyn drives stretch- and flow-elicited PECAM-1 phosphorylation

(2008) Yi-Jen Chiu et al.   JOURNAL OF CELL BIOLOGY

Mechanotransduction in development: a growing role for contractility

(2008) Michele A. Wozniak et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Environmental sensing through focal adhesions

(2008) Benjamin Geiger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

(2008) Ning Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Serial analysis of the vascular endothelial transcriptome under static and shear stress conditions

(2008) Tian Jiao Chu et al.   PHYSIOLOGICAL GENOMICS

Mechanical Stretch Induced Interleukin‐18 (IL‐18) Expression through Angiotensin Subtype 1 Receptor (AT1R) and Endothelin‐1 in Cardiomyocytes

(2008) Toshio Naka et al.   PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY

A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate

(2008) H. Iwasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular basis of the mammalian pressure-sensitive ion channels: Focus on vascular mechanotransduction

(2008) Joost H.A. Folgering et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Tensegrity-based mechanosensing from macro to micro

(2008) Donald E. Ingber   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology

(2008) Peter F Davies   Nature clinical practice. Cardiovascular medicine

Computational representation and hemodynamic characterization of in vivo acquired severe stenotic renal artery geometries using turbulence modeling

(2007) George C. Kagadis et al.   MEDICAL ENGINEERING & PHYSICS