Relationship Between Redox Status and Cell Fate in Immunity and Autoimmunity

Long-Term N-Acetylcysteine Therapy in Systemic Sclerosis Interstitial Lung Disease: A Retrospective Study

(2017) E. Rosato et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Redox regulation of protein kinases

(2013) Aoife Corcoran et al.   FEBS Journal

Apoptosis of Rheumatoid Arthritis Fibroblast-Like Synoviocytes: Possible Roles of Nitric Oxide and the Thioredoxin 1

(2013) Huili Li et al.   MEDIATORS OF INFLAMMATION

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

New tricks from an old dog: Mitochondrial redox signaling in cellular inflammation

(2013) Martin Pelletier et al.   SEMINARS IN IMMUNOLOGY

Autophagy and Autoimmunity Crosstalks

(2013) Abhisek Bhattacharya et al.   Frontiers in Immunology

Autophagy regulates TNFα-mediated joint destruction in experimental arthritis

(2012) Neng-Yu Lin et al.   ANNALS OF THE RHEUMATIC DISEASES

Redox Regulation of T-Cell Function: From Molecular Mechanisms to Significance in Human Health and Disease

(2012) Pravin Kesarwani et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen Peroxide As an Immunological Transmitter Regulating Autoreactive T Cells

(2012) Rikard Holmdahl et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive Oxygen Species Production in the Phagosome: Impact on Antigen Presentation in Dendritic Cells

(2012) Fiorella Kotsias et al.   ANTIOXIDANTS & REDOX SIGNALING

N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: A randomized, double-blind, placebo-controlled trial

(2012) Zhi-Wei Lai et al.   ARTHRITIS AND RHEUMATISM

Processing of proteins in autophagy vesicles of antigen-presenting cells generates citrullinated peptides recognized by the immune system

(2012) Jamie M. Ireland et al.   Autophagy

Autophagy in immunity

(2012) Xu-Jie Zhou et al.   Autophagy

Macroautophagy is deregulated in murine and human lupus T lymphocytes

(2012) Frédéric Gros et al.   Autophagy

Mitochondrial dysfunction in antiphospholipid syndrome: implications in the pathogenesis of the disease and effects of coenzyme Q10 treatment

(2012) C. Perez-Sanchez et al.   BLOOD

X chromosome gene methylation in peripheral lymphocytes from monozygotic twins discordant for scleroderma

(2012) C. Selmi et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Role of peroxynitrite-modified biomolecules in the etiopathogenesis of systemic lupus erythematosus

(2012) Rizwan Ahmad et al.   CLINICAL AND EXPERIMENTAL MEDICINE

The Role of Oxidative Stress in Anti-tumor Necrosis Factor Antibody Treatment in Crohn´s Disease

(2012) V. Kupcova et al.   CURRENT MEDICINAL CHEMISTRY

Resveratrol in Medicinal Chemistry: A Critical Review of its Pharmacokinetics, Drug-Delivery, and Membrane Interactions

(2012) A. R. Neves et al.   CURRENT MEDICINAL CHEMISTRY

Role of autophagy in immunity and autoimmunity, with a special focus on systemic lupus erythematosus

(2012) Marina Pierdominici et al.   FASEB JOURNAL

T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy

(2012) Cristiano Alessandri et al.   FASEB JOURNAL

Differential oxidative modification of proteins in MRL+/+ and MRL/lpr mice: Increased formation of lipid peroxidation-derived aldehyde-protein adducts may contribute to accelerated onset of autoimmune response

(2012) Gangduo Wang et al.   FREE RADICAL RESEARCH

Oxidative stress as a potential biomarker for determining disease activity in patients with Rheumatoid Arthritis

(2012) Sunanda Kundu et al.   FREE RADICAL RESEARCH

Altered redox state and apoptosis in the pathogenesis of systemic lupus erythematosus

(2012) Dilip Shah et al.   IMMUNOBIOLOGY

p53 Contributes to Quercetin-Induced Apoptosis in Human Rheumatoid Arthritis Fibroblast-like Synoviocytes

(2012) Peng Xiao et al.   INFLAMMATION

Reduced apoptosis correlates with enhanced autophagy in synovial tissues of rheumatoid arthritis

(2012) Ke Xu et al.   INFLAMMATION RESEARCH

PINK1- and Parkin-mediated mitophagy at a glance

(2012) Seok Min Jin et al.   JOURNAL OF CELL SCIENCE

LPS induced inflammatory responses in human peripheral blood mononuclear cells is mediated through NOX4 and Gi-alpha dependent PI-3kinase signalling

(2012) Anta Ngkelo et al.   Journal of Inflammation-London

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

Protein tyrosine phosphatases in lymphocyte activation and autoimmunity

(2012) Inmoo Rhee et al.   NATURE IMMUNOLOGY

Hypoxia—a key regulator of angiogenesis and inflammation in rheumatoid arthritis

(2012) Sofia Konisti et al.   Nature Reviews Rheumatology

Neutrophil-derived reactive oxygen species in SSc

(2012) T. C. Barnes et al.   RHEUMATOLOGY

Resveratrol modulates murine collagen-induced arthritis by inhibiting Th17 and B-cell function

(2011) Gao Xuzhu et al.   ANNALS OF THE RHEUMATIC DISEASES

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Gender Disparity in Susceptibility to Oxidative Stress and Apoptosis Induced by Autoantibodies Specific to RLIP76 in Vascular Cells

(2011) Paola Matarrese et al.   ANTIOXIDANTS & REDOX SIGNALING

Increasing levels of serum antioxidant status, total antioxidant power, in systemic sclerosis

(2011) Fumihide Ogawa et al.   CLINICAL RHEUMATOLOGY

Oxidized Human Beta2-Glycoprotein I: Its Impact on Innate Immune Cells

(2011) B. Buttari et al.   CURRENT MOLECULAR MEDICINE

Defective Autophagy in Fibroblasts May Contribute to Fibrogenesis in Autoimmune Processes

(2011) Domenico Del Principe et al.   CURRENT PHARMACEUTICAL DESIGN

Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation

(2011) Pei-Yi Tsai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Serum level of oxidative stress marker is dramatically low in patients with rheumatoid arthritis treated with tocilizumab

(2011) Makoto Hirao et al.   RHEUMATOLOGY INTERNATIONAL

Redox Remodeling Allows and Controls B-Cell Activation and Differentiation

(2010) Roberta Vené et al.   ANTIOXIDANTS & REDOX SIGNALING

Taurine: A Potential Novel Addition to the Anti-Systemic Sclerosis Weaponry

(2010) Mohammad Kazem Fallahzadeh et al.   ARCHIVES OF MEDICAL RESEARCH

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

Analyses of T cell phenotype and function reveal an altered T cell homeostasis in systemic sclerosis

(2010) Antonello Giovannetti et al.   CLINICAL IMMUNOLOGY

The Beclin 1 interactome

(2010) Congcong He et al.   CURRENT OPINION IN CELL BIOLOGY

Dietary supplementation of resveratrol attenuates chronic colonic inflammation in mice

(2010) Susana Sánchez-Fidalgo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasis

(2010) Craig M. Walsh et al.   IMMUNOLOGICAL REVIEWS

Curcumin attenuates inflammatory response in IL-1β-induced human synovial fibroblasts and collagen-induced arthritis in mouse model

(2010) Dong-Oh Moon et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Immunomodulatory and therapeutic activity of curcumin

(2010) Raghvendra M. Srivastava et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Protection of Hepatocyte Cells from the Effects of Oxidative Stress by Treatment with Vitamin E in Conjunction with DTT

(2010) Jen-Hsiang Tsai et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Immunosuppressive Effect of Quercetin on Dendritic Cell Activation and Function

(2010) R.-Y. Huang et al.   JOURNAL OF IMMUNOLOGY

The NRF2 gene variant, -653G/A, is associated with nephritis in childhood-onset systemic lupus erythematosus

(2010) EJ Córdova et al.   LUPUS

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Molecular mechanisms of necroptosis: an ordered cellular explosion

(2010) Peter Vandenabeele et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Recent Developments in Vitamin E and Immune Response

(2010) Simin Nikbin Meydan et al.   NUTRITION REVIEWS

The Nonphagocytic NADPH Oxidase Duox1 Mediates a Positive Feedback Loop During T Cell Receptor Signaling

(2010) J. Kwon et al.   Science Signaling

Regulation of autophagy by ROS: physiology and pathology

(2010) Ruth Scherz-Shouval et al.   TRENDS IN BIOCHEMICAL SCIENCES

N-acetylcysteine infusion reduces the resistance index of renal artery in the early stage of systemic sclerosis

(2009) Edoardo Rosato et al.   ACTA PHARMACOLOGICA SINICA

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Aberrant Reactive Oxygen and Nitrogen Species Generation in Rheumatoid Arthritis (RA): Causes and Consequences for Immune Function, Cell Survival, and Therapeutic Intervention

(2009) Darren C. Phillips et al.   ANTIOXIDANTS & REDOX SIGNALING

Autoantibody against one of the antioxidant repair enzymes, methionine sulfoxide reductase A, in systemic sclerosis: association with pulmonary fibrosis and vascular damage

(2009) Fumihide Ogawa et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

PARP-1 is involved in autophagy induced by DNA damage

(2009) José Antonio Muñoz-Gámez et al.   Autophagy

Synovial B cells of rheumatoid arthritis express ZAP-70 which increases the survival and correlates with the inflammatory and autoimmune phenotype

(2009) Barbara Tolusso et al.   CLINICAL IMMUNOLOGY

The effect of anti-TNF agent on oxidation status in patients with ankylosing spondylitis

(2009) Murat Karkucak et al.   CLINICAL RHEUMATOLOGY

The treatment with N-acetylcysteine of Raynaud’s phenomenon and ischemic ulcers therapy in sclerodermic patients: a prospective observational study of 50 patients

(2009) Edoardo Rosato et al.   CLINICAL RHEUMATOLOGY

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Vascular Abnormalities, Paraoxonase Activity, and Dysfunctional HDL in Primary Antiphospholipid Syndrome

(2009) Marietta Charakida   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Regulation of Mature ADAM17 by Redox Agents for L-Selectin Shedding

(2009) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

Selective Oxidation of DNA Topoisomerase 1 Induces Systemic Sclerosis in the Mouse

(2009) A. Servettaz et al.   JOURNAL OF IMMUNOLOGY

Scleroderma

(2009) Armando Gabrielli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Developments in the scientific understanding of rheumatoid arthritis

(2009) Jörg J Goronzy et al.   ARTHRITIS RESEARCH & THERAPY

Redox Regulation of Cell Survival

(2008) Dunyaporn Trachootham et al.   ANTIOXIDANTS & REDOX SIGNALING

The antioxidant resveratrol protects against chondrocyte apoptosis via effects on mitochondrial polarization and ATP production

(2008) Mandar Dave et al.   ARTHRITIS AND RHEUMATISM

Redox state, cell death and autoimmune diseases: A gender perspective

(2008) Elena Ortona et al.   AUTOIMMUNITY REVIEWS

Is the generation of neo-antigenic determinants by free radicals central to the development of autoimmune rheumatoid disease?

(2008) Helen R. Griffiths   AUTOIMMUNITY REVIEWS

Autoimmunity and oxidatively modified autoantigens

(2008) Biji T. Kurien et al.   AUTOIMMUNITY REVIEWS

Detection of Catalase as a major protein target of the lipid peroxidation product 4-HNE and the lack of its genetic association as a risk factor in SLE

(2008) Anil D'souza et al.   BMC Medical Genetics

A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress

(2008) Q Huang et al.   CELL DEATH AND DIFFERENTIATION

Apoptosis in the Homeostasis of the Immune System and in Human Immune Mediated Diseases

(2008) R. Paganelli et al.   CURRENT PHARMACEUTICAL DESIGN

Decreased severity of experimental autoimmune encephalomyelitis during resveratrol administration is associated with increased IL-17+IL-10+ T cells, CD4− IFN-γ+ cells, and decreased macrophage IL-6 expression

(2008) Toby J. Imler et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

(2008) Huafeng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systemic Lupus Erythematosus

(2008) Anisur Rahman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autoantibodies to the C-terminal subunit of RLIP76 induce oxidative stress and endothelial cell apoptosis in immune-mediated vascular diseases and atherosclerosis

(2007) P. Margutti et al.   BLOOD