Tumor-Selective, Futile Redox Cycle-Induced Bystander Effects Elicited by NQO1 Bioactivatable Radiosensitizing Drugs in Triple-Negative Breast Cancers

Catalase Abrogates  -Lapachone-Induced PARP1 Hyperactivation-Directed Programmed Necrosis in NQO1-Positive Breast Cancers

(2013) E. A. Bey et al.   MOLECULAR CANCER THERAPEUTICS

An NQO1 Substrate with Potent Antitumor Activity That Selectively Kills by PARP1-Induced Programmed Necrosis

(2012) X. Huang et al.   CANCER RESEARCH

Modulating Endogenous NQO1 Levels Identifies Key Regulatory Mechanisms of Action of  -Lapachone for Pancreatic Cancer Therapy

(2011) L. S. Li et al.   CLINICAL CANCER RESEARCH

β-Lapachone Significantly Increases the Effect of Ionizing Radiation to Cause Mitochondrial Apoptosis via JNK Activation in Cancer Cells

(2011) Moon-Taek Park et al.   PLoS One

Prostate Cancer Radiosensitization through Poly(ADP-Ribose) Polymerase-1 Hyperactivation

(2010) Y. Dong et al.   CANCER RESEARCH

 -Lapachone Micellar Nanotherapeutics for Non-Small Cell Lung Cancer Therapy

(2010) E. Blanco et al.   CANCER RESEARCH

Poly(ADP-Ribose) Polymerase Is Hyperactivated in Homologous Recombination-Defective Cells

(2010) P. Gottipati et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Intratumoral Delivery of  -Lapachone via Polymer Implants for Prostate Cancer Therapy

(2008) Y. Dong et al.   CLINICAL CANCER RESEARCH