Mono- and Dithiol Glutaredoxins in the Trypanothione-Based Redox Metabolism of Pathogenic Trypanosomes

Determination of acidity and nucleophilicity in thiols by reaction with monobromobimane and fluorescence detection

(2013) Florencia Sardi et al.   ANALYTICAL BIOCHEMISTRY

Iron–Sulfur Cluster Binding by Mitochondrial Monothiol Glutaredoxin-1 of Trypanosoma brucei: Molecular Basis of Iron–Sulfur Cluster Coordination and Relevance for Parasite Infectivity

(2012) Bruno Manta et al.   ANTIOXIDANTS & REDOX SIGNALING

The Multidomain Thioredoxin-Monothiol Glutaredoxins Represent a Distinct Functional Group

(2011) Bastian Hoffmann et al.   ANTIOXIDANTS & REDOX SIGNALING

Low-Molecular-Mass Antioxidants in Parasites

(2011) R. Luise Krauth-Siegel et al.   ANTIOXIDANTS & REDOX SIGNALING

TheE. coliMonothiol Glutaredoxin GrxD Forms Homodimeric and Heterodimeric FeS Cluster Containing Complexes

(2011) N. Yeung et al.   BIOCHEMISTRY

ArabidopsisChloroplastic Glutaredoxin C5 as a Model to Explore Molecular Determinants for Iron-Sulfur Cluster Binding into Glutaredoxins

(2011) Jérémy Couturier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure ofArabidopsischloroplastic monothiol glutaredoxin AtGRXcp

(2010) Lenong Li et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The crystal structure of human GLRX5: iron–sulfur cluster co-ordination, tetrameric assembly and monomer activity

(2010) Catrine Johansson et al.   BIOCHEMICAL JOURNAL

Cytosolic Monothiol Glutaredoxins Function in Intracellular Iron Sensing and Trafficking via Their Bound Iron-Sulfur Cluster

(2010) Ulrich Mühlenhoff et al.   Cell Metabolism

Functional characterization of methionine sulfoxide reductase A from Trypanosoma spp.

(2010) Diego G. Arias et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Dithiol Glutaredoxins of African Trypanosomes Have Distinct Roles and Are Closely Linked to the Unique Trypanothione Metabolism

(2010) Sevgi Ceylan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts

(2010) Hong Ye et al.   JOURNAL OF CLINICAL INVESTIGATION

Structural and Biochemical Characterization of Yeast Monothiol Glutaredoxin Grx6

(2010) Ming Luo et al.   JOURNAL OF MOLECULAR BIOLOGY

Iron metabolism in trypanosomatids, and its crucial role in infection

(2010) M. C. TAYLOR et al.   PARASITOLOGY

Conformational analysis and design of cross-strand disulfides in antiparallel β-sheets

(2010) S. Indu et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A Disruption in Iron-Sulfur Center Biogenesis via Inhibition of Mitochondrial Dithiol Glutaredoxin 2 May Contribute to Mitochondrial and Cellular Iron Dysregulation in Mammalian Glutathione-Depleted Dopaminergic Cells: Implications for Parkinson's Disease

(2009) Donna W. Lee et al.   ANTIOXIDANTS & REDOX SIGNALING

Cloning, Expression, and Characterization of a Dithiol Glutaredoxin from Trypanosoma cruzi

(2009) Vanina E. Marquez et al.   ANTIOXIDANTS & REDOX SIGNALING

Biochemical Characterization of Dithiol Glutaredoxin 8 fromSaccharomyces cerevisiae: The Catalytic Redox Mechanism Redux†

(2009) Elisabeth Eckers et al.   BIOCHEMISTRY

Structural Basis for Delivery of the Intact [Fe2S2] Cluster by Monothiol Glutaredoxin

(2009) Thomas Iwema et al.   BIOCHEMISTRY

Trypanothione efficiently intercepts nitric oxide as a harmless iron complex in trypanosomatid parasites

(2009) Alessio Bocedi et al.   FASEB JOURNAL

Properties of the Thioredoxin Fold Superfamily Are Modulated by a Single Amino Acid Residue

(2009) Guoping Ren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutaredoxins: roles in iron homeostasis

(2009) Nicolas Rouhier et al.   TRENDS IN BIOCHEMICAL SCIENCES

Maturation of Iron-Sulfur Proteins in Eukaryotes: Mechanisms, Connected Processes, and Diseases

(2008) Roland Lill et al.   Annual Review of Biochemistry

Two Novel Monothiol Glutaredoxins fromSaccharomyces cerevisiaeProvide Further Insight into Iron-Sulfur Cluster Binding, Oligomerization, and Enzymatic Activity of Glutaredoxins†

(2008) Nikola Mesecke et al.   BIOCHEMISTRY

Kinetic and Mechanistic Characterization and Versatile Catalytic Properties of Mammalian Glutaredoxin 2: Implications for Intracellular Roles†

(2008) Molly M. Gallogly et al.   BIOCHEMISTRY

Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism

(2008) R. Luise Krauth-Siegel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Insights into the redox biology of Trypanosoma cruzi: Trypanothione metabolism and oxidant detoxification

(2008) Florencia Irigoín et al.   FREE RADICAL BIOLOGY AND MEDICINE

QuantifyingEscherichia coliGlutaredoxin-3 Substrate Specificity Using Ligand-induced Stability

(2008) Tobias H. Elgán et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monothiol Glutaredoxin-1 Is an Essential Iron-Sulfur Protein in the Mitochondrion of African Trypanosomes

(2008) Marcelo A. Comini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Aspects of the Distinct Biochemical Properties of Glutaredoxin 1 and Glutaredoxin 2 from Saccharomyces cerevisiae

(2008) Karen Fulan Discola et al.   JOURNAL OF MOLECULAR BIOLOGY

A Novel Group of Glutaredoxins in the cis-Golgi Critical for Oxidative Stress Resistance

(2008) Nikola Mesecke et al.   MOLECULAR BIOLOGY OF THE CELL

Expression Pattern of Human Glutaredoxin 2 Isoforms: Identification and Characterization of Two Testis/Cancer Cell-Specific Isoforms

(2007) Maria Elisabet Lönn et al.   ANTIOXIDANTS & REDOX SIGNALING

Cloning, functional analysis, and mitochondrial localization of Trypanosoma brucei monothiol glutaredoxin-1

(2007) Michael Filser et al.   BIOLOGICAL CHEMISTRY