Redox Regulation of Protein Tyrosine Phosphatases: Structural and Chemical Aspects

Toxicological Disruption of Signaling Homeostasis: Tyrosine Phosphatases as Targets

(2010) James M. Samet et al.   Annual Review of Pharmacology and Toxicology

Organelle-Targetable Fluorescent Probes for Imaging Hydrogen Peroxide in Living Cells via SNAP-Tag Protein Labeling

(2010) Duangkhae Srikun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PTP1B: a double agent in metabolism and oncogenesis

(2010) Shu-Chin Yip et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mining the Thiol Proteome for Sulfenic Acid Modifications Reveals New Targets for Oxidation in Cells

(2009) Stephen E. Leonard et al.   ACS Chemical Biology

Orchestrating Redox Signaling Networks through Regulatory Cysteine Switches

(2009) Candice E. Paulsen et al.   ACS Chemical Biology

The Chemical Biology of Protein Phosphorylation

(2009) Mary Katherine Tarrant et al.   Annual Review of Biochemistry

Crystal Structure of the Human Lymphoid Tyrosine Phosphatase Catalytic Domain: Insights into Redox Regulation,

(2009) Sophia J. Tsai et al.   BIOCHEMISTRY

Thiol and Sulfenic Acid Oxidation of AhpE, the One-Cysteine Peroxiredoxin fromMycobacterium tuberculosis: Kinetics, Acidity Constants, and Conformational Dynamics

(2009) Martín Hugo et al.   BIOCHEMISTRY

Redox Regulation of SH2-Domain-Containing Protein Tyrosine Phosphatases by Two Backdoor Cysteines

(2009) Cheng-Yu Chen et al.   BIOCHEMISTRY

Protection of a single-cysteine redox switch from oxidative destruction: On the functional role of sulfenyl amide formation in the redox-regulated enzyme PTP1B

(2009) Santhosh Sivaramakrishnan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome

(2009) Alastair J. Barr et al.   CELL

Pseudophosphatases: Grab and Hold on

(2009) Nicholas K. Tonks   CELL

Redox Regulation of the Human Dual Specificity Phosphatase YVH1 through Disulfide Bond Formation

(2009) Christopher A. Bonham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recent Advances in the Discovery of Competitive Protein Tyrosine Phosphatase 1B Inhibitors for the Treatment of Diabetes, Obesity, and Cancer

(2009) Andrew P. Combs   JOURNAL OF MEDICINAL CHEMISTRY

Simultaneous Detection of Cysteine Sulfenate, Sulfinate, and Sulfonate during Cysteine Interfacial Ozonolysis

(2009) Shinichi Enami et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages

(2009) Gabriela Molina et al.   Nature Chemical Biology

Thiol-Based Redox Switches in Eukaryotic Proteins

(2008) Nicolas Brandes et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidative inactivation of protein tyrosine phosphatase 1B by organic hydroperoxides

(2008) Sanjib Bhattacharya et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Biologically relevant chemical properties of peroxymonophosphate (O3POOH)

(2008) Jason N. LaButti et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Evidence for a Morin Type Intramolecular Cyclization of an Alkene with a Phenylsulfenic Acid Group in Neutral Aqueous Solution

(2008) Kripa Keerthi et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Discovering mechanisms of signaling-mediated cysteine oxidation

(2008) Leslie B Poole et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Expanding the functional diversity of proteins through cysteine oxidation

(2008) Khalilah G Reddie et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Protein tyrosine phosphatases: regulatory mechanisms

(2008) Jeroen den Hertog et al.   FEBS Journal

Redox-based regulation of signal transduction: Principles, pitfalls, and promises

(2008) Yvonne M.W. Janssen-Heininger et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of ROS signal transduction by NADPH oxidase 4 localization

(2008) Kai Chen et al.   JOURNAL OF CELL BIOLOGY

Identification of Small Molecular Weight Inhibitors of Src Homology 2 Domain-Containing Tyrosine Phosphatase 2 (SHP-2) via in Silico Database Screening Combined with Experimental Assay

(2008) Wen-Mei Yu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology

A modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cells

(2008) B. Boivin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidation of archaeal peroxiredoxin involves a hypervalent sulfur intermediate

(2008) T. Nakamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reactivity of Sulfenic Acid in Human Serum Albumin†

(2007) Lucía Turell et al.   BIOCHEMISTRY