Identification of a Key Lysine Residue in Heat Shock Protein 90 Required for Azole and Echinocandin Resistance in Aspergillus fumigatus

Casein kinase 2 phosphorylation of Hsp90 threonine 22 modulates chaperone function and drug sensitivity

(2015) Mehdi Mollapour et al.   Oncotarget

Filamentous fungal-specific septin AspE is phosphorylated in vivo and interacts with actin, tubulin and other septins in the human pathogen Aspergillus fumigatus

(2013) Praveen Rao Juvvadi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A novel small molecule hydroxamate preferentially inhibits HDAC6 activity and tumour growth

(2013) M Kaliszczak et al.   BRITISH JOURNAL OF CANCER

Transcriptional Activation of Heat Shock Protein 90 Mediated Via a Proximal Promoter Region as Trigger of Caspofungin Resistance in Aspergillus fumigatus

(2013) Frédéric Lamoth et al.   JOURNAL OF INFECTIOUS DISEASES

In Vitro Activity of Calcineurin and Heat Shock Protein 90 Inhibitors against Aspergillus fumigatus Azole- and Echinocandin-Resistant Strains

(2012) F. Lamoth et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Heat Shock Protein 90 Is Required for Conidiation and Cell Wall Integrity in Aspergillus fumigatus

(2012) Frédéric Lamoth et al.   EUKARYOTIC CELL

Clinical epidemiology of 960 patients with invasive aspergillosis from the PATH Alliance registry

(2012) William J. Steinbach et al.   JOURNAL OF INFECTION

Conformational Switching of the Molecular Chaperone Hsp90 via Regulated Phosphorylation

(2012) Joanna Soroka et al.   MOLECULAR CELL

Lysine Deacetylases Hda1 and Rpd3 Regulate Hsp90 Function thereby Governing Fungal Drug Resistance

(2012) Nicole Robbins et al.   Cell Reports

Post-translational modifications of Hsp90 and their contributions to chaperone regulation

(2011) Mehdi Mollapour et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Localization and activity of the calcineurin catalytic and regulatory subunit complex at the septum is essential for hyphal elongation and proper septation in Aspergillus fumigatus

(2011) Praveen Rao Juvvadi et al.   MOLECULAR MICROBIOLOGY

Catch me if you can: Mass spectrometry-based phosphoproteomics and quantification strategies

(2011) Beate Eyrich et al.   PROTEOMICS

N-Terminal Acetylation of Cellular Proteins Creates Specific Degradation Signals

(2010) C.-S. Hwang et al.   SCIENCE

Aspergillus fumigatusCalcipressin CbpA Is Involved in Hyphal Growth and Calcium Homeostasis

(2009) Nadthanan Pinchai et al.   EUKARYOTIC CELL

Activity of MGCD290, a Hos2 Histone Deacetylase Inhibitor, in Combination with Azole Antifungals against Opportunistic Fungal Pathogens

(2009) M. A. Pfaller et al.   JOURNAL OF CLINICAL MICROBIOLOGY

A Novel Motif in Fungal Class 1 Histone Deacetylases Is Essential for Growth and Development of Aspergillus

(2009) Martin Tribus et al.   MOLECULAR BIOLOGY OF THE CELL

Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease

(2009) Leah E. Cowen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hsp90 Governs Echinocandin Resistance in the Pathogenic Yeast Candida albicans via Calcineurin

(2009) Sheena D. Singh et al.   PLoS Pathogens

Treatment of Aspergillosis: Clinical Practice Guidelines of the Infectious Diseases Society of America

(2008) Thomas J. Walsh et al.   CLINICAL INFECTIOUS DISEASES

The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype

(2008) Leah E. Cowen   NATURE REVIEWS MICROBIOLOGY