Multicenter, Randomized Clinical Trial To Compare the Safety and Efficacy of LFF571 and Vancomycin for Clostridium difficile Infections

Pharmacokinetics of LFF571 and Vancomycin in Patients with Moderate Clostridium difficile Infections

(2014) Suraj G. Bhansali et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Vancomycin, Metronidazole, or Tolevamer for Clostridium difficile Infection: Results From Two Multinational, Randomized, Controlled Trials

(2014) Stuart Johnson et al.   CLINICAL INFECTIOUS DISEASES

The relationship between phenotype, ribotype, and clinical disease in human Clostridium difficile isolates

(2013) Paul E. Carlson et al.   ANAEROBE

Antimicrobial activity of LFF571 and three treatment agents against Clostridium difficile isolates collected for a pan-European survey in 2008: clinical and therapeutic implications

(2013) S. B. Debast et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

ComparativeIn VitroActivities of LFF571 against Clostridium difficile and 630 Other Intestinal Strains of Aerobic and Anaerobic Bacteria

(2012) Diane M. Citron et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Efficacy of LFF571 in a Hamster Model of Clostridium difficile Infection

(2012) Anna Trzasko et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A First-in-Human, Randomized, Double-Blind, Placebo-Controlled, Single- and Multiple-Ascending Oral Dose Study To Assess the Safety and Tolerability of LFF571 in Healthy Volunteers

(2012) Lillian S. L. Ting et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mechanism of Action of and Mechanism of Reduced Susceptibility to the Novel Anti-Clostridium difficile Compound LFF571

(2012) J. A. Leeds et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Discovery of LFF571: An Investigational Agent for Clostridium difficile Infection

(2012) Matthew J. LaMarche et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fidaxomicin versus vancomycin for infection with Clostridium difficile in Europe, Canada, and the USA: a double-blind, non-inferiority, randomised controlled trial

(2012) Oliver A Cornely et al.   LANCET INFECTIOUS DISEASES

Lack of Association between Clinical Outcome of Clostridium difficile Infections, Strain Type, and Virulence-Associated Phenotypes

(2011) S. Sirard et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Fidaxomicin versus Vancomycin forClostridium difficileInfection

(2011) Thomas J. Louie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA)

(2010) Stuart H. Cohen et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY