期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 57, 期 5, 页码 2372-2375出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.02622-12
关键词
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资金
- INSERM [U914]
- Ministere de l'Education Nationale et de la Recherche [UPRES-EA3539]
- Universite Paris XI, France
- European Community [TEMPOtest-QC, HEALTH-2009-241742, R-GNOSIS, FP7/HEALTH-F3-2011-282512, MAGIC-BULLET, FP7/HEALTH-F3-2001-278232]
- Ecole Nationale Veterinaire de Maisons-Alfort (ENVA) through an INSERM-ENVA
Screening of extended-spectrum beta-lactamase (ESBL)-producing Gram-negative bacteria in companion animals living in the Paris area in France identified a high rate of CTX-M-15-producing Klebsiella pneumoniae. Those isolates were recovered during the 2010-2011 period from both infections and asymptomatic colonizations. Sequence typing revealed that most of these isolates belonged to sequence type ST274. Interestingly, the bla(CTX-M-15) gene was located on a specific and novel plasmid scaffold. These findings highlight that companion animals may be reservoirs for CTX-M-15-producing K. pneumoniae evolving separately from the human reservoir of CTX-M-15 producers.
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