Characterization of Potential Drug Targets Farnesyl Diphosphate Synthase and Geranylgeranyl Diphosphate Synthase in Schistosoma mansoni

Infection and treatment immunizations for successful parasite vaccines

(2013) Francisca Mutapi et al.   TRENDS IN PARASITOLOGY

The N-Terminus and the Chain-Length Determination Domain Play a Role in the Length of the Isoprenoid Product of the Bifunctional Toxoplasma gondii Farnesyl Diphosphate Synthase

(2012) Zhu-Hong Li et al.   BIOCHEMISTRY

Susceptibility or resistance of praziquantel in human schistosomiasis: a review

(2012) Wei Wang et al.   PARASITOLOGY RESEARCH

Terpene Biosynthesis: Modularity Rules

(2011) Eric Oldfield et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In VitroandIn VivoAntiplasmodial Activities of Risedronate and Its Interference with Protein Prenylation in Plasmodium falciparum

(2011) Fabiana Morandi Jordão et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Targeting Isoprenoid Biosynthesis for Drug Discovery: Bench to Bedside

(2010) Eric Oldfield   ACCOUNTS OF CHEMICAL RESEARCH

Lipophilic Bisphosphonates Are Potent Inhibitors of Plasmodium Liver-Stage Growth

(2010) A. P. Singh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Praziquantel and Schistosomiasis

(2010) Alexander Dömling et al.   ChemMedChem

Molecular Characterization of a Novel Geranylgeranyl Pyrophosphate Synthase fromPlasmodiumParasites

(2010) Jennifer D. Artz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipophilic Pyridinium Bisphosphonates: Potent γδT Cell Stimulators

(2009) Yonghui Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lipophilic Bisphosphonates as Dual Farnesyl/Geranylgeranyl Diphosphate Synthase Inhibitors: An X-ray and NMR Investigation

(2009) Yonghui Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rescuing the bottom billion through control of neglected tropical diseases

(2009) Peter J Hotez et al.   LANCET

The genome of the blood fluke Schistosoma mansoni

(2009) Matthew Berriman et al.   NATURE

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

Targeting a Uniquely Nonspecific Prenyl Synthase with Bisphosphonates to Combat Cryptosporidiosis

(2008) Jennifer D. Artz et al.   CHEMISTRY & BIOLOGY

Anti-infectives Targeting the isoprenoid pathway ofToxoplasma gondii

(2008) Silvia NJ Moreno et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Bisphosphonate Inhibition of aPlasmodiumFarnesyl Diphosphate Synthase and a General Method for Predicting Cell-Based Activity from Enzyme Data

(2008) Dushyant Mukkamala et al.   JOURNAL OF MEDICINAL CHEMISTRY

Oxamniquine, praziquantel and lovastatin association in the experimental Schistosomiasis mansoni

(2008) Neusa Araújo et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ