标题
Evaluating Aziridinyl Nitrobenzamide Compounds as Leishmanicidal Prodrugs
作者
关键词
-
出版物
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 58, Issue 1, Pages 370-377
出版商
American Society for Microbiology
发表日期
2013-10-29
DOI
10.1128/aac.01459-13
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- TheREnantiomer of the Antitubercular Drug PA-824 as a Potential Oral Treatment for Visceral Leishmaniasis
- (2013) Stephen Patterson et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Evaluating 5-Nitrofurans as Trypanocidal Agents
- (2013) Christopher Bot et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- An Essential Type I Nitroreductase fromLeishmania majorCan Be Used to Activate Leishmanicidal Prodrugs
- (2013) Andrew A. Voak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genotoxicity profile of fexinidazole--a drug candidate in clinical development for human African trypanomiasis (sleeping sickness)
- (2012) D. Tweats et al. MUTAGENESIS
- The Anti-Trypanosome Drug Fexinidazole Shows Potential for Treating Visceral Leishmaniasis
- (2012) S. Wyllie et al. Science Translational Medicine
- Activation of Benznidazole by Trypanosomal Type I Nitroreductases Results in Glyoxal Formation
- (2011) Belinda S. Hall et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Leishmaniasis chemotherapy—challenges and opportunities
- (2011) S.L. Croft et al. CLINICAL MICROBIOLOGY AND INFECTION
- Trypanocidal Activity of Nitroaromatic Prodrugs: Current Treatments and Future Perspectives
- (2011) Shane R. Wilkinson et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- 1-Aryl-4-nitro-1H-imidazoles, a new promising series for the treatment of human African trypanosomiasis
- (2011) Bernadette Bourdin Trunz et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Nifurtimox Activation by Trypanosomal Type I Nitroreductases Generates Cytotoxic Nitrile Metabolites
- (2011) Belinda S. Hall et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Luciferase-Expressing Leishmania infantum Allows the Monitoring of Amastigote Population Size, In Vivo, Ex Vivo and In Vitro
- (2011) Grégory Michel et al. PLoS Neglected Tropical Diseases
- Trypanocidal Activity of Aziridinyl Nitrobenzamide Prodrugs
- (2010) C. Bot et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A combined luciferase imaging and reverse transcription polymerase chain reaction assay for the study of Leishmania amastigote burden and correlated mouse tissue transcript fluctuations
- (2010) Emilie de La Llave et al. CELLULAR MICROBIOLOGY
- Leishmaniasis, an emerging infection in travelers
- (2010) Androula Pavli et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Climate Change and Risk of Leishmaniasis in North America: Predictions from Ecological Niche Models of Vector and Reservoir Species
- (2010) Camila González et al. PLoS Neglected Tropical Diseases
- Fexinidazole – A New Oral Nitroimidazole Drug Candidate Entering Clinical Development for the Treatment of Sleeping Sickness
- (2010) Els Torreele et al. PLoS Neglected Tropical Diseases
- In vivo Imaging of Transgenic Leishmania Parasites in a Live Host
- (2010) Colin J. Thalhofer et al. Jove-Journal of Visualized Experiments
- Exploiting the Drug-Activating Properties of a Novel Trypanosomal Nitroreductase
- (2009) B. S. Hall et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- NITROFURANTOIN: THE RETURN OF AN OLD FRIEND IN THE WAKE OF GROWING RESISTANCE
- (2009) BJU INTERNATIONAL
- A phase I trial of PR-104, a nitrogen mustard prodrug activated by both hypoxia and aldo-keto reductase 1C3, in patients with solid tumors
- (2009) Michael B. Jameson et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- A Phase I/II Clinical Trial in Localized Prostate Cancer of an Adenovirus Expressing Nitroreductase with CB1984
- (2009) Prashant Patel et al. MOLECULAR THERAPY
- Kinetoplastids: related protozoan pathogens, different diseases
- (2008) Ken Stuart et al. JOURNAL OF CLINICAL INVESTIGATION
- Design of anticancer prodrugs for reductive activation
- (2008) Yu Chen et al. MEDICINAL RESEARCH REVIEWS
- A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes
- (2008) Shane R. Wilkinson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication
- (2007) Brent E. Korba et al. ANTIVIRAL RESEARCH
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started