Investigation of the Functional Role of P-Glycoprotein in Limiting the Oral Bioavailability of Lumefantrine

Gender differences in pharmacokinetics of lumefantrine and its metabolite desbutyl-lumefantrine in rats

(2012) et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Simultaneous determination of nine model compounds in permeability samples using RP-HPLC: Application to prove the cassette administration principle in single pass intestinal perfusion study in rats

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Desbutyl-Lumefantrine Is a Metabolite of Lumefantrine with PotentIn VitroAntimalarial Activity That May Influence Artemether-Lumefantrine Treatment Outcome

(2011) Rina P. M. Wong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Prediction of human absorption of a trioxane antimalarial drug (CDRI 99/411) using an in-house validated in situ single-pass intestinal perfusion model

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Study on in situ and in vivo absorption kinetics of phenytoin by modulating P-glycoprotein with verapamil in rats

(2011) Prasad Neerati et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Intravenous pharmacokinetics, oral bioavailability, dose proportionality and in situ permeability of anti-malarial lumefantrine in rats

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Small intestinal efflux mediated by MRP2 and BCRP shifts sulfasalazine intestinal permeability from high to low, enabling its colonic targeting

(2009) Arik Dahan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Determination of lumefantrine in rat plasma by liquid–liquid extraction using LC–MS/MS with electrospray ionization: Assay development, validation and application to a pharmacokinetic study

(2009) Wahajuddin et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Prodrugs: design and clinical applications

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