The Antibiotic Resistance Arrow of Time: Efflux Pump Induction Is a General First Step in the Evolution of Mycobacterial Drug Resistance

Meta-Analysis of Clinical Studies Supports the Pharmacokinetic Variability Hypothesis for Acquired Drug Resistance and Failure of Antituberculosis Therapy

(2012) Jotam G. Pasipanodya et al.   CLINICAL INFECTIOUS DISEASES

Rifampicin Reduces Susceptibility to Ofloxacin in Rifampicin-resistantMycobacterium tuberculosisthrough Efflux

(2011) Gail E. Louw et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A new evolutionary and pharmacokinetic–pharmacodynamic scenario for rapid emergence of resistance to single and multiple anti-tuberculosis drugs

(2011) Jotam G Pasipanodya et al.   CURRENT OPINION IN PHARMACOLOGY

Pharmacokinetic/pharmacodynamic-based treatment of disseminatedMycobacterium avium

(2011) Devyani Deshpande et al.   Future Microbiology

Multidrug-Resistant Tuberculosis Not Due to Noncompliance but to Between-Patient Pharmacokinetic Variability

(2011) Shashikant Srivastava et al.   JOURNAL OF INFECTIOUS DISEASES

Rapid Assessment of Antibacterial Activity against Mycobacterium ulcerans by Using Recombinant Luminescent Strains

(2010) T. Zhang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Moxifloxacin Pharmacokinetics/Pharmacodynamics and Optimal Dose and Susceptibility Breakpoint Identification for Treatment of Disseminated Mycobacterium avium Infection

(2010) D. Deshpande et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ethambutol Optimal Clinical Dose and Susceptibility Breakpoint Identification by Use of a Novel Pharmacokinetic-Pharmacodynamic Model of Disseminated Intracellular Mycobacterium avium

(2010) D. Deshpande et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Efflux‐Pump–Derived Multiple Drug Resistance to Ethambutol Monotherapy inMycobacterium tuberculosisand the Pharmacokinetics and Pharmacodynamics of Ethambutol

(2010) Shashikant Srivastava et al.   JOURNAL OF INFECTIOUS DISEASES

Two Distinct Major Facilitator Superfamily Drug Efflux Pumps Mediate Chloramphenicol Resistance in Streptomyces coelicolor

(2009) J. J. Vecchione et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics-Pharmacodynamics of Pyrazinamide in a Novel In Vitro Model of Tuberculosis for Sterilizing Effect: a Paradigm for Faster Assessment of New Antituberculosis Drugs

(2009) T. Gumbo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Balancing Act: Efflux/Influx in Mycobacterial Drug Resistance

(2009) G. E. Louw et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Neutrophils Are the Predominant Infected Phagocytic Cells in the Airways of Patients With Active Pulmonary TB

(2009) Seok-Yong Eum et al.   CHEST