期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 55, 期 5, 页码 2446-2450出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00808-10
关键词
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资金
- Ministry of Agriculture, Forestry and Fisheries of Japan
- Japan Society for the Promotion of Science (JSPS)
- Grants-in-Aid for Scientific Research [23658081, 22780069] Funding Source: KAKEN
Lacticin Q, a lactococcal pore-forming bacteriocin, shows activity toward Gram-positive bacteria but not Gram-negative bacteria. Lacticin Q did not induce permeability of the outer membrane of Gram-negative bacteria. Experiments using model membranes containing outer membrane components suggested that lacticin Q binds to the outer membrane of Gram-negative bacteria but is unable to penetrate it. The lack of activity of lacticin Q was attributed to physicochemical features of the outer membrane components.
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