期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 54, 期 6, 页码 2735-2737出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01774-09
关键词
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Antimicrobial susceptibilities were determined for 1,586 isolates of Stenotrophomonas maltophilia from globally diverse medical centers using the Clinical Laboratory Standards Institute broth microdilution method. The combination trimethoprim-sulfamethoxazole (96.0% of isolates susceptible at <= 2 mu g/ml trimethoprim and 38 mu g/ml sulfamethoxazole) and tigecycline (95.5% of isolates sussceptible at <= 2 mu g/ml) were the only antimicrobials tested with >94% susceptibility in all regions. Susceptibility rates for other commonly used were lower than expected and varied geographically. This in vitro data supports tigecycline as a potential candidate for clinical investigations into S. maltophilia infections.
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