4.7 Article

Antimicrobial Susceptibilities of Health Care-Associated and Community-Associated Strains of Methicillin-Resistant Staphylococcus aureus from Hospitalized Patients in Canada, 1995 to 2008

期刊

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 54, 期 5, 页码 2265-2268

出版社

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01717-09

关键词

-

资金

  1. Public Health Agency of Canada
  2. CNISP hospital

向作者/读者索取更多资源

We determined the in vitro antimicrobial susceptibilities of 7,942 methicillin-resistant Staphylococcus aureus (MRSA) isolates obtained from patients hospitalized in 48 Canadian hospitals from 1995 to 2008. Regional variations in susceptibilities were identified. The dissemination of community-associated strains in Canada appears to have contributed to increased susceptibility of MRSA to several non-beta-lactam antimicrobial agents in the past decade. Reduced susceptibility to glycopeptides was not identified.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

Article Public, Environmental & Occupational Health

Similar duration of viral shedding of the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) delta variant between vaccinated and incompletely vaccinated individuals

Christopher E. Kandel, Andra Banete, Maureen Taylor, Andrea Llanes, Janine McCready, Gloria Crowl, Matthew Young, Angel X. Li, Emily Chien, Winfield Yim, Lily Yip, Robert Kozak, Allison J. McGeer, Samira Mubareka, Jeff E. Powis

Summary: There was no difference in viral shedding between outpatients with coronavirus disease 2019 (COVID-19) due to the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) delta (delta) variant who received 2 vaccine doses at 7 days after symptom onset and those who did not receive the vaccine, with SARS-CoV-2 cultured from 2 (7%) of 28 and 1 (4%) of 26 outpatients, respectively.

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2023)

Letter Public, Environmental & Occupational Health

Severity of SARS-CoV-2 omicron infection in vaccinated and unvaccinated residents of long-term care homes

Ahmed Vanker, Lara de Waal, Allison McGeer, Matthew Morgan

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2023)

Letter Immunology

Environmental Testing of Surfaces in the Room of a Patient With Monkeypox

Matthew P. Muller, Sharmistha Mishra, Allison McGeer, Samir Patel, Jonathan Gubbay, Maan Hasso, Adrienne K. Chan, Robert Kozak, Jerome A. Leis, Darrell S. Tan

CLINICAL INFECTIOUS DISEASES (2023)

Article Immunology

Adverse Events Following Immunization With mRNA and Viral Vector Vaccines in Individuals With Previous Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection From the Canadian National Vaccine Safety Network

Julie A. Bettinger, Michael A. Irvine, Hennady P. Shulha, Louis Valiquette, Matthew P. Muller, Otto G. Vanderkooi, James D. Kellner, Karina A. Top, Manish Sadarangani, Allison McGeer, Jennifer E. Isenor, Kimberly Marty, Phyumar Soe, Gaston De Serres

Summary: This study examined the short-term safety of COVID-19 vaccines in adults with a previous history of SARS-CoV-2 infection. It found that adults with moderate or severe previous infection were more likely to experience health events after each vaccine dose, while the risk associated with previous infection was attenuated after subsequent doses.

CLINICAL INFECTIOUS DISEASES (2023)

Article Public, Environmental & Occupational Health

Risk factors for mechanical complications of peripherally inserted central catheters in children

David J. Greencorn, Stefan Kuhle, Lingyun Ye, Kieran J. Moore, Ketan P. Kulkarni, Joanne M. Langley

Summary: Risk factors for mechanical complications in children with PICCs have been identified, which can improve best practices for PICC insertion and care.

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2023)

Article Genetics & Heredity

Genome screening, reporting, and genetic counseling for healthy populations

Selina Casalino, Erika Frangione, Monica Chung, Georgia MacDonald, Sunakshi Chowdhary, Chloe Mighton, Hanna Faghfoury, Yvonne Bombard, Lisa Strug, Trevor J. Pugh, Jared Simpson, Saranya Arnoldo, Navneet Aujla, Erin Bearss, Alexandra Binnie, Bjug Borgundvaag, Howard Chertkow, Marc Clausen, Marc Dagher, Luke Devine, David Di Iorio, Steven Marc Friedman, Chun Yiu Jordan Fung, Anne-Claude Gingras, Lee W. Goneau, Deepanjali Kaushik, Zeeshan Khan, Elisa Lapadula, Tiffany Lu, Tony Mazzulli, Allison McGeer, Shelley L. McLeod, Gregory Morgan, David Richardson, Harpreet Singh, Seth Stern, Ahmed Taher, Iris Wong, Natasha Zarei, Elena Greenfeld, Limin Hao, Matthew Lebo, William Lane, Abdul Noor, Jennifer Taher, Jordan Lerner-Ellis

Summary: Rapid advancements in genome sequencing technology have improved our understanding of the relationship between genes and human disease. This study collected blood samples from COVID-19 patients and performed genome sequencing to analyze the data. The researchers developed a comprehensive report that includes information on disease risks, genetic variants, and ancestry. They emphasize the importance of genetic counseling and offer counseling and referrals for clinically significant findings.

HUMAN GENETICS (2023)

Article Immunology

Invasive Pneumococcal Disease in High-risk Children: A 10-Year Retrospective Study

Jacqui van Warmerdam, Aaron Campigotto, Ari Bitnun, Georgina MacDougall, Melanie Kirby-Allen, Blake Papsin, Allison McGeer, Upton Allen, Shaun K. Morris

Summary: Despite the availability of pneumococcal vaccines, children with high-risk conditions are still susceptible to invasive pneumococcal disease. Insufficient vaccination is the main factor contributing to the occurrence of the disease.

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2023)

Correction Microbiology

Divergent SARS-CoV-2 variant emerges in white-tailed deer with deer-to-human transmission (vol 7, pg 2011, 2022)

Bradley Pickering, Oliver Lung, Finlay Maguire, Peter Kruczkiewicz, Jonathon D. Kotwa, Tore Buchanan, Marianne Gagnier, Jennifer L. Guthrie, Claire M. Jardine, Alex Marchand-Austin, Ariane Masse, Heather McClinchey, Kuganya Nirmalarajah, Patryk Aftanas, Juliette Blais-Savoie, Hsien-Yao Chee, Emily Chien, Winfield Yim, Andra Banete, Bryan D. Griffin, Lily Yip, Melissa Goolia, Matthew Suderman, Mathieu Pinette, Greg Smith, Daniel Sullivan, Josip Rudar, Oksana Vernygora, Elizabeth Adey, Michelle Nebroski, Guillaume Goyette, Andres Finzi, Genevieve Laroche, Ardeshir Ariana, Brett Vahkal, Marceline Cote, Allison J. McGeer, Larissa Nituch, Samira Mubareka, Jeff Bowman

NATURE MICROBIOLOGY (2023)

Article Immunology

Evaluating the Impact of Statin Use on Influenza Vaccine Effectiveness and Influenza Infection in Older Adults

Hannah Chung, Michael A. Campitelli, Sarah A. Buchan, Aaron Campigotto, Branson Chen, Natasha S. Crowcroft, Vinita Dubey, Jonathan B. Gubbay, Timothy Karnauchow, Kevin Katz, Allison J. McGeer, J. Dayre McNally, Samira Mubareka, Michelle Murti, David C. Richardson, Laura C. Rosella, Kevin L. Schwartz, Marek Smieja, George Zahariadis, Jeffrey C. Kwong

Summary: The effectiveness of influenza vaccine against laboratory-confirmed influenza was similar between statin users and nonusers. However, statin users had a higher risk of influenza infection compared to nonusers, regardless of vaccination status. This study suggests that statin use may affect the effectiveness of influenza vaccine and increase the risk of influenza infection.

CLINICAL INFECTIOUS DISEASES (2023)

Article Public, Environmental & Occupational Health

Coronavirus disease 2019 (COVID-19) outbreak on an in-patient medical unit associated with unrecognized exposures in common areas-Epidemiological and whole-genome sequencing investigation

Dylan C. Kain, Sandra Isabel, Mariana Abdulnoor, Karel Boissinot, Richard De Borja, Amanda Filkin, Bernard Lam, Jason Li, Ilinca Lungu, Liz McCreight, Allison McGeer, Tony Mazzulli, Aimee Paterson, Philip Zuzarte, Felicia Vincelli, Cassandra Bergwerff, Ramzi Fattouh, Jared T. Simpson, Jennie Johnstone

Summary: During the COVID-19 pandemic, a severe SARS-CoV-2 outbreak occurred in a hospital in Toronto, Canada, from November 2020 to January 2021. The outbreak involved 8 patients and 10 staff and resulted in 3 patient deaths. Investigation revealed that patients cared for in geriatric chairs at the nursing station were at high risk for both acquiring and transmitting SARS-CoV-2. Therefore, it is important to consider the risk of informal patient care settings and prioritize room-based care during high-risk periods or outbreaks.

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2023)

Article Economics

The epidemiology and healthcare costs of community-acquired pneumonia in Ontario, Canada: a population-based cohort study

Ryan O'Reilly, Hong Lu, Jeffrey C. C. Kwong, Allison McGeer, Teresa To, Beate Sander

Summary: The present study aimed to determine the short- and long-term healthcare costs associated with community-acquired pneumonia (CAP) from the healthcare payer perspective in Ontario, Canada. Through a retrospective population-based matched cohort study, it was found that CAP is associated with significantly increased acute and long-term healthcare costs compared to unexposed subjects. This study highlights the burden of CAP in both the inpatient and outpatient setting, and will inform strategic healthcare planning for future interventions and healthcare programs.

JOURNAL OF MEDICAL ECONOMICS (2023)

Article Infectious Diseases

Use of whole genome sequencing to identify low-frequency mutations in SARS-CoV-2 patients treated with remdesivir

Kuganya Nirmalarajah, Winfield Yim, Patryk Aftanas, Angel X. Li, Altynay Shigayeva, Lily Yip, Zoe Zhong, Allison J. Mcgeer, Finlay Maguire, Samira Mubareka, Robert Kozak

Summary: This study investigated the effects of Remdesivir (RDV) treatment on intra-host SARS-CoV-2 diversity and low-frequency mutations in moderately ill hospitalized COVID-19 patients. The results showed minimal intra-host variability and few low-frequency variants in patients receiving short courses of RDV, suggesting little selective pressure.

INFLUENZA AND OTHER RESPIRATORY VIRUSES (2023)

Article Infectious Diseases

Evaluation of Clinical Case Definitions for Respiratory Syncytial Virus Lower Respiratory Tract Infection in Young Children

Janet A. Englund, Rachel A. Cohen, Veronique Bianco, Joseph B. Domachowske, Joanne M. Langley, Shabir A. Madhi, Khalequ Zaman, Agustin Bueso, Ana Ceballos, Luis Cousin, Sanjay Gandhi, Olivier Gruselle, Lisa Jose, Nicola P. Klein, Anthonet Koen, Thanyawee Puthanakit, Meng Shi, Peter Silas, Auchara Tangsathapornpong, Jamaree Teeratakulpisarn, Timo Vesikari, Gerco Haars, Amanda Leach, Sonia K. Stoszek, Ilse Dieussaert

Summary: Respiratory syncytial virus (RSV) causes respiratory illnesses ranging from common cold to moderate and severe lung disease. Symptoms and methods used to identify/track RSV disease are not always the same in different settings. Three definitions of RSV disease were compared with the World Health Organization (WHO) recommendation in 2015. A universal definition of RSV disease and severity is needed for effective treatment and prevention measures.

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY (2023)

Article Geriatrics & Gerontology

Nursing home crowding and its association with outbreak-associated respiratory infection in Ontario, Canada before the COVID-19 pandemic (2014-19): a retrospective cohort study

Pamela Leece, Michael Whelan, Andrew P. Costa, Nick Daneman, Jennie Johnstone, Allison McGeer, Paula Rochon, Kevin L. Schwartz, Kevin A. Brown

Summary: Studies conducted before the COVID-19 pandemic have found that crowding in nursing homes is associated with higher incidence of respiratory infections and mortality. This association is consistent across various respiratory pathogens. Decreasing crowding is important for resident wellbeing and reducing the transmission of respiratory pathogens.

LANCET HEALTHY LONGEVITY (2023)

Letter Immunology

Environmental Surface Contamination With Monkeypox Virus in the Ambulatory Setting in Toronto, Canada

Sharon Sukhdeo, Matthew Muller, Allison McGeer, Jerome A. Leis, Adrienne Chan, Jonathan B. Gubbay, Samir Patel, Saman Khan, Stephen Perusini, Xinliu Angel Li, Robert Kozak, Sharmistha Mishra, Darrell H. S. Tan, Christopher Kandel

OPEN FORUM INFECTIOUS DISEASES (2023)

暂无数据