期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 55, 期 2, 页码 904-909出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00962-10
关键词
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资金
- Ontario Agency for Health Protection and Promotion
- Ministry of Science, Technology and Productive Innovation, Government of Argentina
The first allele of a 16S rRNA methyltransferase gene, rmtD2, conferring very high resistance to all clinically available aminoglycosides, was detected in 7/1,064 enterobacteria collected in 2007. rmtD2 was located on a conjugative plasmid in a Tn2670-like element inside a structure similar to that of rmtD1 but probably having an independent assembly. rmtD2 has been found since 1996 to 1998 mainly in Enterobacter and Citrobacter isolates, suggesting a possible reservoir in these genera. This presumption deserves monitoring by continuous surveillance.
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