期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 53, 期 4, 页码 1686-1689出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01467-08
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资金
- Fondo de Investigaciones Sanitarias [FI05/00856]
- Agencia Espanola de Cooperacion Internacional
- Spanish Network for Research in Infectious Diseases [REIPI RD06/0008]
- Instituto de Salud Carlos III [PI05/32]
- Astellas
- Merck
- Pfizer
- Gilead
- Schering-Plough
The antifungal susceptibility profiles of 77 clinical strains of Mucorales species, identified by internal transcribed spacer sequencing, were analyzed. MICs obtained at 24 and 48 h were compared. Amphotericin B was the most active agent against all isolates, except for Cunninghamella and Apophysomyces isolates. Posaconazole also showed good activity for all species but Cunninghamella bertholletiae. Voriconazole had no activity against any of the fungi tested. Terbinafine showed good activity, except for Rhizopus oryzae, Mucor circinelloides, and Rhizomucor variabilis isolates.
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