期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 53, 期 6, 页码 2613-2615出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01657-08
关键词
-
资金
- CyDex Pharmaceuticals Inc.
- Pfizer
- Schering-Plough
Targeted airway delivery of antifungals as prophylaxis against invasive aspergillosis may lead to high lung drug concentrations while avoiding toxicities associated with systemically administered agents. We evaluated the effectiveness of aerosolizing the intravenous formulation of voriconazole as prophylaxis against invasive pulmonary aspergillosis caused by Aspergillus fumigatus in an established murine model. Inhaled voriconazole significantly improved survival and limited the extent of invasive disease, as assessed by histopathology, compared to control and amphotericin B treatments.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据