4.7 Article

Characterization of pUO-StVR2, a Virulence-Resistance Plasmid Evolved from the pSLT Virulence Plasmid of Salmonella enterica Serovar Typhimurium

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ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 52, 期 12, 页码 4514-4517

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AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00563-08

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  1. Fundacion para el Fomento en Asturias de la Investigacion Cientifica Aplicada y la Tecnologia [BP03-014]
  2. Fondo de Investigacion Sanitaria, Ministerio de Sanidad y Consumo, Spain [PI02-0172, PI05-2489]

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pUO-StVR2 is a virulence-resistance plasmid which originated from pSLT of Salmonella enterica serovar Typhimurium through acquisition of a complex resistance island, flanked by regions that provide a toxin-antitoxin system and an iron uptake system. The presence of resistance and virulence determinants on the same plasmid allows coselection of both properties, potentially increasing health risks.

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