期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 52, 期 9, 页码 3447-3450出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00553-08
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In vitro treatment of Echinococcus multilocularis and Echinococcus granulosus larval stages with the antimalarials dihydroartemisinin and artesunate (10 to 40 mu M) exhibited promising results, while 6 weeks of in vivo treatment of mice infected with E. multilocularis metacestodes (200 mg/kg of body weight/day) had no effect. However, combination treatments of both drugs with albendazole led to a substantial but statistically not significant reduction in parasite weight compared to results with albendazole alone.
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