Spatiotemporal Regulation of Small GTPases as Revealed by Probes Based on the Principle of Förster Resonance Energy Transfer (FRET): Implications for Signaling and Pharmacology

Reversible Dimerization ofAequorea victoriaFluorescent Proteins Increases the Dynamic Range of FRET-Based Indicators

(2010) Ippei Kotera et al.   ACS Chemical Biology

Simultaneous Visualization of Protumorigenic Src and MT1-MMP Activities with Fluorescence Resonance Energy Transfer

(2010) M. Ouyang et al.   CANCER RESEARCH

Ras and Calcium Signaling Pathways Converge at Raf1 via the Shoc2 Scaffold Protein

(2010) Sayaka Yoshiki et al.   MOLECULAR BIOLOGY OF THE CELL

Bright cyan fluorescent protein variants identified by fluorescence lifetime screening

(2010) Joachim Goedhart et al.   NATURE METHODS

Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion

(2009) Shuh Narumiya et al.   CANCER AND METASTASIS REVIEWS

Mechanisms for concentrating Rho1 during cytokinesis

(2009) S. Yoshida et al.   GENES & DEVELOPMENT

Tuberous Sclerosis Tumor Suppressor Complex-like Complexes Act as GTPase-activating Proteins for Ral GTPases

(2009) Ryutaro Shirakawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of RhoG activity is mediated by a syndecan 4–synectin–RhoGDI1 complex and is reversed by PKCα in a Rac1 activation pathway

(2009) Arye Elfenbein et al.   JOURNAL OF CELL BIOLOGY

A clathrin-dependent pathway leads to KRas signaling on late endosomes en route to lysosomes

(2009) Albert Lu et al.   JOURNAL OF CELL BIOLOGY

Ras/MAPK signaling from endomembranes

(2009) Nicole Fehrenbacher et al.   Molecular Oncology

Coordination of Rho GTPase activities during cell protrusion

(2009) Matthias Machacek et al.   NATURE

Visualization of small GTPase activity with fluorescence resonance energy transfer-based biosensors

(2009) Kazuhiro Aoki et al.   Nature Protocols

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endogenous Activation Patterns of Cdc42 GTPase Within Drosophila Embryos

(2009) D. Kamiyama et al.   SCIENCE

Cell–cell junction formation: The role of Rap1 and Rap1 guanine nucleotide exchange factors

(2008) Willem-Jan Pannekoek et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Directional migration of neural crest cells in vivo is regulated by Syndecan-4/Rac1 and non-canonical Wnt signaling/RhoA

(2008) H. K. Matthews et al.   DEVELOPMENT

Directional control of cell motility through focal adhesion positioning and spatial control of Rac activation

(2008) Nan Xia et al.   FASEB JOURNAL

Characterization of an improved donor fluorescent protein for Förster resonance energy transfer microscopy

(2008) Richard N. Day et al.   JOURNAL OF BIOMEDICAL OPTICS

Imaging of Rab5 activity identifies essential regulators for phagosome maturation

(2008) Masahiro Kitano et al.   NATURE

Fluorescent protein FRET pairs for ratiometric imaging of dual biosensors

(2008) Hui-wang Ai et al.   NATURE METHODS

Differential RhoA Dynamics in Migratory and Stationary Cells Measured by FRET and Automated Image Analysis

(2008) John Paul Eichorst et al.   PLoS One

Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors

(2008) M. Ouyang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatiotemporal activation of Rac1 for engulfment of apoptotic cells

(2008) M. Nakaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo

(2008) M. Laurin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantification of Local Morphodynamics and Local GTPase Activity by Edge Evolution Tracking

(2008) Yuki Tsukada et al.   PLoS Computational Biology