Article
Multidisciplinary Sciences
Nadja Mallock, Andrea Rabenstein, Solveig Gernun, Peter Laux, Christoph Hutzler, Susanne Karch, Gabriele Koller, Frank Henkler-Stephani, Maria Kristina Parr, Oliver Pogarell, Andreas Luch, Tobias Ruether
Summary: The emergence of e-cigarettes has led to increased consumption among adolescents in the US. The JUUL's success is linked to its high nicotine delivery capacity, which is limited to 20 mg/mL in Europe. A study comparing tobacco cigarettes, the initial and modified European JUUL versions showed lower nicotine delivery and reduced urge to smoke/vape with the JUUL variants compared to cigarettes. However, the pod design modification did not show significant differences in the first ten puffs, only becoming evident after longer usage time.
SCIENTIFIC REPORTS
(2021)
Article
Psychiatry
Kerim Abdelkhalek, Mathias Rhein, Maximilian Deest, Vanessa Buchholz, Stefan Bleich, Ralf Lichtinghagen, Benjamin Vyssoki, Helge Frieling, Marc Muschler, Phileas Johannes Proskynitopoulos, Alexander Glahn
Summary: This study investigated the regulation of BDNF protein levels and gene methylation in smokers and during smoking cessation. The results showed that BDNF plasma levels and methylation levels were lower in healthy controls compared to smokers at all time points. BDNF levels decreased significantly during the cessation period. Female smokers had significantly lower plasma BDNF levels than healthy controls, while male and female smokers showed higher mean methylation rates than non-smokers at baseline. In male smokers, mean methylation levels decreased significantly during the cessation period.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Environmental Sciences
Greg Hartwell, Matt Egan, Jamie Brown, Triantafyllos Pliakas, Mark Petticrew
Summary: This study found that dual users of combustible tobacco and e-cigarettes were more likely to access smoking cessation services compared to smokers not using e-cigarettes. Similar associations were found for dual users of combustible tobacco and nicotine replacement therapy. The study also provided evidence on key psychosocial factors influencing smokers' decision-making in accessing smoking cessation services.
Article
Psychology, Clinical
N. Rycroft, L. Hogarth, J. MacKillop, L. Dawkins
Summary: The study found that there was comparable dependency levels between smokers and vapers, but vapers were more sensitive to price and more likely to choose money over e-cigarettes when primed by money cues.
ADDICTIVE BEHAVIORS
(2021)
Article
Public, Environmental & Occupational Health
J. P. Tripathy, P. V. Maha Lakshmi
Summary: The study aimed to identify latent classes of adult tobacco or nicotine-based product users in India, compare their sociodemographic distribution and quitting behaviour, and explore the association of quitting behaviour and time to first tobacco use with class membership. Data from the Global Adult Tobacco Survey in India were analyzed, resulting in the identification of five latent classes with significant differences in sociodemographic characteristics and tobacco use behavior. The findings of this study are important for tailoring interventions to different classes of tobacco product users.
Review
Respiratory System
Harold J. Farber, Manuel Conrado Pacheco Gallego, Panagis Galiatsatos, Patricia Folan, Thomas Lamphere, Smita Pakhale
Summary: Electronic cigarettes entered the market without thorough preclinical testing or long-term safety trials, and are associated with severe harms such as product explosions and severe lung diseases. The World Health Organization does not endorse e-cigarettes as cessation aids, and healthcare providers should not prescribe or recommend them for tobacco dependent individuals.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2021)
Article
Substance Abuse
Sarah E. Jackson, Jamie Brown, Martin J. Jarvis
Summary: From 2012 to 2019, there was an increase in nicotine product use among high school students in the United States, but it was not accompanied by a similar increase in population burden of nicotine dependence. Cigarette users exhibited the highest level of dependence, while e-cigarette users showed lower levels of dependence.
Review
Biochemistry & Molecular Biology
Segev Barak, Koral Goltseker
Summary: Studies indicate that intervening in the reconsolidation of alcohol and nicotine/tobacco memories may help reduce relapse, serving as a potential strategy to suppress relapse to alcohol drinking and tobacco smoking.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Editorial Material
Substance Abuse
Robert West, Sharon Cox
Summary: The 1988 US Surgeon General's Report on Nicotine Addiction highlighted the addictive nature of tobacco and the role of nicotine in addiction. While the report's main conclusions have held up well over 30 years, it is now understood that different nicotine products vary in addictiveness and there is a need for updated thinking on this topic.
Article
Public, Environmental & Occupational Health
Christine M. Steeger, Alyssa F. Harlow, Jessica L. Barrington-Trimis, Patricia Simon, Karl G. Hill, Adam M. Leventhal
Summary: The use of flavored tobacco is associated with a lower likelihood of quitting smoking, and specific flavor categories reduce the chances of quitting across different tobacco products. Current use of flavored tobacco products is associated with a reduced likelihood of quitting.
PREVENTIVE MEDICINE
(2022)
Article
Substance Abuse
Sarah S. Dermody, Katelyn M. Tessier, Ellen Meier, Mustafa Al'Absi, Rachel L. Denlinger-Apte, David J. Drobes, Joni Jensen, Joseph S. Koopmeiners, Lauren R. Pacek, Jennifer W. Tidey, Ryan Vandrey, Eric Donny, Dorothy Hatsukami
Summary: The study found that reducing the nicotine content in cigarettes through a nicotine product standard could decrease smoking and improve public health; within the study sample, individuals with higher alcohol use may be less affected by very low nicotine content cigarettes; under experimental conditions, smoking very low nicotine content cigarettes may reduce daily alcohol consumption and the odds of binge drinking.
NICOTINE & TOBACCO RESEARCH
(2021)
Review
Substance Abuse
Eric C. Donny, Cassidy M. White
Summary: Reducing nicotine content in cigarettes to very low levels could benefit public health by decreasing smoking prevalence, reducing cigarette consumption, and increasing smoking cessation. This strategy may have similar positive effects across various populations of smokers, but there could also be negative outcomes such as withdrawal symptoms and the emergence of illicit markets.
INTERNATIONAL JOURNAL OF DRUG POLICY
(2022)
Article
Psychology, Clinical
Anna Maria Abi Nehme, XiangYang Lou, Xinyu Yan, Ji-Hyun Lee, Ramzi G. Salloum
Summary: This study evaluated the patterns and factors influencing smoking cessation among dual users of e-cigarettes and traditional cigarettes. The results showed that using e-cigarettes has the potential to aid in smoking cessation, but demographic and smoking habit factors have an impact on the outcome of quitting smoking.
ADDICTIVE BEHAVIORS
(2022)
Article
Medicine, General & Internal
Marushka L. Silveira, Colm D. Everard, Eva Sharma, Kristin Lauten, Apostolos A. Alexandridis, Kara Duffy, Ethel Taylor, Eric A. Tolliver, Carlos Blanco, Wilson M. Compton, Heather L. Kimmel, Timothy Iafolla, Andrew Hyland, Benjamin W. Chaffee
Summary: This study examined the associations between tobacco use and adverse oral health outcomes. The results showed that smoking was associated with gum disease, loose teeth, and tooth removal, while cigar smoking was associated with precancerous oral lesions. Additionally, hookah smoking was associated with gum disease, and ENDS use was associated with bleeding after brushing or flossing. These findings highlight the importance of longitudinal studies and tobacco cessation counseling in clinical practice.
Article
Substance Abuse
Amy M. Cohn, Adam C. Alexander, Sarah J. Ehlke
Summary: The study found that African American smokers have a higher preference for menthol cigarettes and stronger subjective responses to smoking compared to White smokers. The appeal of menthol cigarettes is associated with smoking intensity and perceptions of cigarette harm.
NICOTINE & TOBACCO RESEARCH
(2022)