Sphingosine 1-Phosphate Receptor Signaling

The role of sphingosine-1-phosphate and its receptors in asthma

(2009) J.J. Ryan et al.   DRUG NEWS & PERSPECTIVES

Ligand-Binding Pocket Shape Differences between Sphingosine 1-Phosphate (S1P) Receptors S1P1and S1P3Determine Efficiency of Chemical Probe Identification by Ultrahigh-Throughput Screening

(2008) Stephan C. Schürer et al.   ACS Chemical Biology

Choreography of Cell Motility and Interaction Dynamics Imaged by Two-Photon Microscopy in Lymphoid Organs

(2008) Michael D. Cahalan et al.   Annual Review of Immunology

Sphingosylphosphorylcholine as a novel calmodulin inhibitor

(2008) Erika Kovacs et al.   BIOCHEMICAL JOURNAL

Sphingosine 1-phosphate chemical biology

(2008) K LYNCH   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Sphingosine-1-phosphate signaling and biological activities in the cardiovascular system

(2008) Y TAKUWA   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Sphingosine-1-phosphate regulation of mammalian development

(2008) M KONO   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Structural modifications of N-arylamide oxadiazoles: Identification of N-arylpiperidine oxadiazoles as potent and selective agonists of CB2

(2008) Erin F. DiMauro et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase

(2008) Shin-ichiro Takashima et al.   CARDIOVASCULAR RESEARCH

Vascular Endothelium As a Contributor of Plasma Sphingosine 1-Phosphate

(2008) Krishnan Venkataraman et al.   CIRCULATION RESEARCH

G protein-coupled receptor kinase 2 positively regulates epithelial cell migration

(2008) Petronila Penela et al.   EMBO JOURNAL

Modulating tone: the overture of S1P receptor immunotherapeutics

(2008) Hugh Rosen et al.   IMMUNOLOGICAL REVIEWS

S1P1Receptor Localization Confers Selectivity for Gi-mediated cAMP and Contractile Responses

(2008) Christopher Kable Means et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery and Optimization of a Novel Series ofN-Arylamide Oxadiazoles as Potent, Highly Selective and Orally Bioavailable Cannabinoid Receptor 2 (CB2) Agonists

(2008) Yuan Cheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Sphingosine-1-phosphate receptors: Biology and therapeutic potential in kidney disease

(2008) S.-K. Jo et al.   KIDNEY INTERNATIONAL

Full Pharmacological Efficacy of a Novel S1P1 Agonist That Does Not Require S1P-Like Headgroup Interactions

(2008) P. J. Gonzalez-Cabrera et al.   MOLECULAR PHARMACOLOGY

Local Not Systemic Modulation of Dendritic Cell S1P Receptors in Lung Blunts Virus-Specific Immune Responses to Influenza

(2008) D. Marsolais et al.   MOLECULAR PHARMACOLOGY

Dendritic cell PAR1–S1P3 signalling couples coagulation and inflammation

(2008) Frank Niessen et al.   NATURE

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanisms of the negative inotropic effects of sphingosine-1-phosphate on adult mouse ventricular myocytes

(2007) Lee K. Landeen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Caveolae as Organizers of Pharmacologically Relevant Signal Transduction Molecules

(2007) Hemal H. Patel et al.   Annual Review of Pharmacology and Toxicology

Statins induce S1P1 receptors and enhance endothelial nitric oxide production in response to high-density lipoproteins

(2007) J Igarashi et al.   BRITISH JOURNAL OF PHARMACOLOGY