Article
Cardiac & Cardiovascular Systems
Elizabeth H. Stephens, Abhinav A. Talwar, Paul J. Devlin, Osama Eltayeb, Michael C. Monge, Sabrina Tsao, Carl L. Backer
Summary: This study reviewed nonfenestrated extracardiac Fontan and Fontan conversion operations over 24 years, showing low operative mortality rates. Risk factors for adverse outcomes included prolonged cardiopulmonary bypass time, preoperative decreased dominant ventricular function, and longer length of stay.
ANNALS OF THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Friso M. Rijnberg, Seline F. S. van der Woude, Mark G. Hazekamp, Pieter J. van den Boogaard, Hildo J. Lamb, Covadonga Terol Espinosa de Los Monteros, Lucia J. M. Kroft, Sasa Kenjeres, Tawab Karim, Monique R. M. Jongbloed, Jos J. M. Westenberg, Jolanda J. Wentzel, Arno A. W. Roest
Summary: This study evaluates the adequacy of 16-20mm conduits in adolescent Fontan patients and finds that important blood flow accelerations from the inferior vena cava to the conduit are related to peak VO2.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Takashi Kido, Christoph Stern, Paul Philipp Heinisch, Melchior Burri, Janez Vodiskar, Martina Strbad, Julie Cleuziou, Bettina Ruf, Peter Ewert, Alfred Hager, Juergen Hoerer, Masamichi Ono
Summary: This study aimed to investigate the impact of pulmonary artery size on outcomes after nonfenestrated total cavopulmonary connection. The individual impact of each branch pulmonary artery size was determined in a subgroup of patients with right-sided bidirectional cavopulmonary shunt. The results showed that the pulmonary artery index was significantly associated with the occurrence of chylothorax, and the left pulmonary artery index had a significant predictive value for longer stay in the intensive care unit and adverse events in patients with right-sided bidirectional cavopulmonary shunt.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Salvatore Giannico, Matteo Trezzi, Nicoletta Cantarutti, Giulia Cafiero, Lucilla Rava, Rachele Adorisio, Gianluca Brancaccio, Sonia Albanese, Fabrizio Drago, Adriano Carotti, Antonio Amodeo, Lorenzo Galletti
Summary: Most patients undergoing extracardiac Fontan operation have satisfactory long-term survival, but there are still risks of adverse events and late failure. The risk of late adverse events and heart transplant is associated with the preoperative diagnosis of patients.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Baran Simsek, Arda Ozyuksel, Sener Demiroluk, Murat Saygi, Mehmet S. Bilal
Summary: Early outcomes of intraextracardiac fenestrated Fontan procedure are promising, showing potential to improve prognosis in patients who require palliation as univentricular physiology, especially in cases with complex cardiac anatomy.
JOURNAL OF CARDIAC SURGERY
(2022)
Article
Medicine, General & Internal
Maciej Skubera, Aleksandra Golab, Tomasz Sternalski, Olga Trojnarska, Dariusz Plicner, Monika Smas-Suska, Anna Mazurek-Kula, Agnieszka Bartczak-Rutkowska, Jacek Pajak, Piotr Podolec, Lidia Tomkiewicz-Pajak
Summary: This multicenter study investigated the incidence of thromboembolic complications (TECs) in adult patients after Fontan (FO) surgery. The study found that 23.1% of FO patients had a history of TECs, with pulmonary embolism being the most common complication. The results suggest that TECs occur at a higher rate in FO patients than expected.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
William N. Evans, Ruben J. Acherman, Humberto Restrepo
Summary: This study investigated the gender differences in hepatic fibrosis in extracardiac-Fontan patients. The results showed that females had significantly higher median total fibrosis scores than males, despite similar average age and Fontan duration. No other demographic or clinical factors demonstrated significant gender differences.
JOURNAL OF CARDIAC SURGERY
(2022)
Review
Cardiac & Cardiovascular Systems
Wayne C. Zheng, Melissa G. Y. Lee, Yves D'Udekem
Summary: Some patients with single ventricles who have not undergone the Fontan procedure may achieve long-term survival with balanced hemodynamics. Approximately half of patients may survive for more than 20 years on only a systemic-to-pulmonary artery shunt or bidirectional cavopulmonary shunt with reasonable functional status. For patients with a failing single ventricle, the bidirectional cavopulmonary shunt can serve as an excellent bridge to heart transplantation and may offer better post-transplant survival than those with a Fontan circulation.
ANNALS OF THORACIC SURGERY
(2022)
Article
Medicine, General & Internal
Agnieszka Bartczak-Rutkowska, Lidia Tomkiewicz-Pajak, Katarzyna Kawka-Paciorkowska, Natalia Bajorek, Aleksandra Cieplucha, Mariola Ropacka-Lesiak, Olga Trojnarska
Summary: A study investigated the maternal and fetal outcomes of women who had undergone the Fontan procedure in two Polish medical centers. Among 26 pregnancies, 11 ended in miscarriages and 15 resulted in 16 live births. Fetal complications were observed in 9 live births, with prematurity being the most common. Obstetrical complications occurred in 6 pregnancies, including placental abruption, premature rupture of membranes, and antepartum hemorrhage. Specialized care from experienced cardiologists and obstetricians is necessary for these women.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Makoto Miyake, Jiro Sakamoto, Hirokazu Kondo, Atsushi Iwakura, Hiraku Doi, Toshihiro Tamura
Summary: This study aimed to investigate the long-term outcomes of patients with single-ventricle physiology after the Glenn procedure without the subsequent Fontan procedure. The study found that the 40-year overall survival after the Glenn procedure in patients with single-ventricle physiology was 40.3%. Dominant left ventricular morphology may be associated with better long-term overall survival than dominant right ventricular morphology.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Article
Physiology
Yong Zhang, Minhua Fang, Zengwei Wang, Yu Liu, Chunzhen Zhang, Zhenlong Wang, Huishan Wang
Summary: This study applied preoperative CTA and CFD simulation to predict and verify the outcome of Y-shaped extracardiac conduits Fontan for functional single ventricle. The study compared different conduit structures and found that area-preserving YCPC group had the best outcome, providing more guidance for clinical application.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Friso M. Rijnberg, Luca C. van't Hul, Mark G. Hazekamp, Pieter J. van den Boogaard, Joe F. Juffermans, Hildo J. Lamb, Covadonga Terol Espinosa de Los Monteros, Lucia J. M. Kroft, Sasa Kenjeres, Saskia le Cessie, Monique R. M. Jongbloed, Jos J. M. Westenberg, Arno A. W. Roest, Jolanda J. Wentzel
Summary: This study investigated the relationship between conduit size and haemodynamics in adolescent Fontan patients. The results showed that most patients had relatively undersized conduits, leading to suboptimal haemodynamics.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Surgery
Juliet Emamaullee, Sean Martin, Cameron Goldbeck, Brittany Rocque, Arianna Barbetta, Rohit Kohli, Vaughn Starnes
Summary: This study analyzed the long-term outcomes of patients post-Fontan procedure and found an increased all-cause mortality in Hispanic population and a correlation between the incidence of FALD and age. This emphasizes the need for specific liver surveillance strategies in patients post-Fontan.
Article
Physiology
Gyu-Han Lee, Hyun Jung Koo, Kyung Jin Park, Dong Hyun Yang, Hojin Ha
Summary: This study aimed to characterize the hemodynamics of Fontan patients using 4D Flow MRI and CFD. Hemodynamic parameters were estimated and compared between the two modalities. The results showed that there were discrepancies between 4D Flow MRI and CFD in terms of PFD and VD, highlighting the need for careful consideration when analyzing hemodynamic data from different modalities in Fontan patients.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Thomas G. Wilson, Ajay J. Iyengar, Dominica Zentner, Diana Zannino, Yves d'Udekem, Igor E. Konstantinov
Summary: Liver cirrhosis is a potential complication after the Fontan procedure, and the study aims to identify the associated risk factors and optimal timing of liver screening.
ANNALS OF THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Soh Hosoba, Toshiaki Ito, Makoto Mori, Riku Kato, Koh Kajiyama, Shogo Maeda, Yuji Nakai, Yoshihiro Morishita
Summary: This study describes the approach and perioperative outcomes of totally endoscopic isolated and concomitant surgical aortic valve replacement (AVR) using various valve types. The results demonstrate that endoscopic AVR can safely address concomitant valve diseases.
ANNALS OF THORACIC SURGERY
(2024)