Expression of FcRL4 defines a pro-inflammatory, RANKL-producing B cell subset in rheumatoid arthritis

Rituximab abrogates joint destruction in rheumatoid arthritis by inhibiting osteoclastogenesis

(2011) Maria J H Boumans et al.   ANNALS OF THE RHEUMATIC DISEASES

Cytokine mRNA profiling identifies B cells as a major source of RANKL in rheumatoid arthritis

(2011) L. Yeo et al.   ANNALS OF THE RHEUMATIC DISEASES

The response of T cells to interleukin-6 is differentially regulated by the microenvironment of the rheumatoid synovial fluid and tissue

(2011) Ester Hidalgo et al.   ARTHRITIS AND RHEUMATISM

FcRL4 acts as an adaptive to innate molecular switch dampening BCR signaling and enhancing TLR signaling

(2011) H. W. Sohn et al.   BLOOD

Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity

(2011) A. V. Rubtsov et al.   BLOOD

Attenuation of HIV-associated human B cell exhaustion by siRNA downregulation of inhibitory receptors

(2011) Lela Kardava et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of joint damage and improved clinical outcomes with rituximab plus methotrexate in early active rheumatoid arthritis: the IMAGE trial

(2010) P. P. Tak et al.   ANNALS OF THE RHEUMATIC DISEASES

Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcγ receptor

(2010) Jeremy Sokolove et al.   ARTHRITIS AND RHEUMATISM

Targeting B cells in immune-mediated inflammatory disease: A comprehensive review of mechanisms of action and identification of biomarkers

(2010) Thomas Dörner et al.   PHARMACOLOGY & THERAPEUTICS

Insights into the heterogeneity of human B cells: diverse functions, roles in autoimmunity, and use as therapeutic targets

(2009) Jennifer H. Anolik et al.   IMMUNOLOGIC RESEARCH

Atypical Memory B Cells Are Greatly Expanded in Individuals Living in a Malaria-Endemic Area

(2009) G. E. Weiss et al.   JOURNAL OF IMMUNOLOGY

Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium

(2009) Frances Humby et al.   PLOS MEDICINE

Rituximab inhibits structural joint damage in patients with rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitor therapies

(2008) E Keystone et al.   ANNALS OF THE RHEUMATIC DISEASES

Discriminating gene expression profiles of memory B cell subpopulations

(2008) Götz R.A. Ehrhardt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

(2008) Susan Moir et al.   JOURNAL OF EXPERIMENTAL MEDICINE