Discarded Human Thymus Is a Novel Source of Stable and Long-Lived Therapeutic Regulatory T Cells

Sequential Monitoring and Stability ofEx Vivo-Expanded Autologous and Nonautologous Regulatory T Cells Following Infusion in Nonhuman Primates

(2015) H. Zhang et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Age-associated telomere attrition of lymphocytesin vivois co-ordinated with changes in telomerase activity, composition of lymphocyte subsets and health conditions

(2015) Yun Lin et al.   CLINICAL SCIENCE

Donor Requirements for Regulatory T Cell Suppression of Murine Graft-versus-Host Disease

(2015) Antonio Pierini et al.   JOURNAL OF IMMUNOLOGY

Therapy of type 1 diabetes with CD4+CD25highCD127-regulatory T cells prolongs survival of pancreatic islets — Results of one year follow-up

(2014) Natalia Marek-Trzonkowska et al.   CLINICAL IMMUNOLOGY

Regulatory T Cells as Immunotherapy

(2014) Benjamin D. Singer et al.   Frontiers in Immunology

Third-party umbilical cord blood–derived regulatory T cells prevent xenogenic graft-versus-host disease

(2013) Simrit Parmar et al.   CYTOTHERAPY

Helios+ and Helios- Cells Coexist within the Natural FOXP3+ T Regulatory Cell Subset in Humans

(2013) M. E. Himmel et al.   JOURNAL OF IMMUNOLOGY

Active Demethylation of the Foxp3 Locus Leads to the Generation of Stable Regulatory T Cells within the Thymus

(2013) A. Toker et al.   JOURNAL OF IMMUNOLOGY

Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis

(2013) Hong Nie et al.   NATURE MEDICINE

CD4+Foxp3+ regulatory T cells prolong drug-induced disease remission in (NZBxNZW) F1 lupus mice

(2013) Olivia Weigert et al.   ARTHRITIS RESEARCH & THERAPY

Telomeres and immune competency

(2012) Nan-ping Weng   CURRENT OPINION IN IMMUNOLOGY

Regulatory T-cell therapy for transplantation

(2012) Qizhi Tang et al.   Current Opinion in Organ Transplantation

Long-Term Engraftment of Human Natural T Regulatory Cells in NOD/SCID IL2rγcnull Mice by Expression of Human IL-2

(2012) Sojan Abraham et al.   PLoS One

Collapse of Telomere Homeostasis in Hematopoietic Cells Caused by Heterozygous Mutations in Telomerase Genes

(2012) Geraldine Aubert et al.   PLoS Genetics

Human FoxP3+ regulatory T cells in systemic autoimmune diseases

(2011) Makoto Miyara et al.   AUTOIMMUNITY REVIEWS

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

(2011) M. Di Ianni et al.   BLOOD

Human Th1 and Th17 Cells Exhibit Epigenetic Stability at Signature Cytokine and Transcription Factor Loci

(2011) C. J. Cohen et al.   JOURNAL OF IMMUNOLOGY

Plasticity of Human Regulatory T Cells in Healthy Subjects and Patients with Type 1 Diabetes

(2011) Stephanie A. McClymont et al.   JOURNAL OF IMMUNOLOGY

Identification of T helper type 1–like, Foxp3+ regulatory T cells in human autoimmune disease

(2011) Margarita Dominguez-Villar et al.   NATURE MEDICINE

Massive ex Vivo Expansion of Human Natural Regulatory T Cells (Tregs) with Minimal Loss of in Vivo Functional Activity

(2011) K. L. Hippen et al.   Science Translational Medicine

Moving to tolerance: Clinical application of T regulatory cells

(2011) Alicia N. McMurchy et al.   SEMINARS IN IMMUNOLOGY

Regulatory T cell lineage commitment in the thymus

(2011) Ludger Klein et al.   SEMINARS IN IMMUNOLOGY

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

(2010) C. G. Brunstein et al.   BLOOD

Becoming self-aware: the thymic education of regulatory T cells

(2010) Chan-Wang J Lio et al.   CURRENT OPINION IN IMMUNOLOGY

T regulatory cells and transplantation tolerance

(2010) Vijay S. Gorantla et al.   Transplantation Reviews

Depletion of Specific Cell Populations by Complement Depletion

(2010) Bonnie N. Dittel   Jove-Journal of Visualized Experiments

Quantitative DNA Methylation Analysis of FOXP3 as a New Method for Counting Regulatory T Cells in Peripheral Blood and Solid Tissue

(2009) G. Wieczorek et al.   CANCER RESEARCH

First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127− T regulatory cells

(2009) Piotr Trzonkowski et al.   CLINICAL IMMUNOLOGY

Loss of FOXP3 expression in natural human CD4+CD25+regulatory T cells upon repetitivein vitrostimulation

(2009) Petra Hoffmann et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human T Regulatory Cell Therapy: Take a Billion or So and Call Me in the Morning

(2009) James L. Riley et al.   IMMUNITY

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

IL-6 Signaling in Psoriasis Prevents Immune Suppression by Regulatory T Cells

(2009) W. A. Goodman et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cell Suppression Is Potentiated by Target T Cells in a Cell Contact, IL-35- and IL-10-Dependent Manner

(2009) Lauren W. Collison et al.   JOURNAL OF IMMUNOLOGY

Identification of IL-17-producing FOXP3+ regulatory T cells in humans

(2009) K. S. Voo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activated CD4+CD25+ regulatory T cells inhibit osteoclastogenesis and collagen-induced arthritis

(2008) H Kelchtermans et al.   ANNALS OF THE RHEUMATIC DISEASES

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

(2008) H. J. P. M. Koenen et al.   BLOOD

Expansion of Human Regulatory T-Cells From Patients With Type 1 Diabetes

(2008) A. L. Putnam et al.   DIABETES

A Two-Step Process for Thymic Regulatory T Cell Development

(2008) Chan-Wang Joaquim Lio et al.   IMMUNITY

Human regulatory T cells: role in autoimmune disease and therapeutic opportunities

(2008) Todd M. Brusko et al.   IMMUNOLOGICAL REVIEWS

Telomeres and Aging

(2008) Geraldine Aubert et al.   PHYSIOLOGICAL REVIEWS