The genetics of human obesity

Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations

(2012) Yukinori Okada et al.   NATURE GENETICS

Meta-analysis identifies common variants associated with body mass index in east Asians

(2012) Wanqing Wen et al.   NATURE GENETICS

A genome-wide association meta-analysis identifies new childhood obesity loci

(2012)   NATURE GENETICS

The mystery of missing heritability: Genetic interactions create phantom heritability

(2012) O. Zuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus

(2011) Sébastien Jacquemont et al.   NATURE

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Role of BMI-Associated Loci Identified in GWAS Meta-Analyses in the Context of Common Childhood Obesity in European Americans

(2011) Jianhua Zhao et al.   Obesity

A Genome-wide Study Reveals Copy Number Variants Exclusive to Childhood Obesity Cases

(2010) Joseph T. Glessner et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Exclusion mapping of the Cohen syndrome gene from the Prader-Willi syndrome locus

(2010) Ikuko Kondo et al.   CLINICAL GENETICS

FTO Genetic Variation and Association With Obesity in West Africans and African Americans

(2010) A. Adeyemo et al.   DIABETES

Fine mapping of the association with obesity at the FTO locus in African-derived populations

(2010) Mohamed T. Hassanein et al.   HUMAN MOLECULAR GENETICS

A new highly penetrant form of obesity due to deletions on chromosome 16p11.2

(2010) R. G. Walters et al.   NATURE

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Overexpression of Fto leads to increased food intake and results in obesity

(2010) Chris Church et al.   NATURE GENETICS

Switch from Stress Response to Homeobox Transcription Factors in Adipose Tissue After Profound Fat Loss

(2010) Simon N. Dankel et al.   PLoS One

Olfactomedin 4 down-regulates innate immunity against Helicobacter pylori infection

(2010) W. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The genetics of obesity: FTO leads the way

(2010) Katherine A. Fawcett et al.   TRENDS IN GENETICS

Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups

(2010) André Scherag et al.   PLoS Genetics

Loss-of-Function Mutation in the Dioxygenase-Encoding FTO Gene Causes Severe Growth Retardation and Multiple Malformations

(2009) Sarah Boissel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The HapMap and Genome-Wide Association Studies in Diagnosis and Therapy

(2009) Teri A. Manolio et al.   Annual Review of Medicine

Prevalence of Loss-of-Function FTO Mutations in Lean and Obese Individuals

(2009) D. Meyre et al.   DIABETES

Examination of All Type 2 Diabetes GWAS Loci Reveals HHEX-IDE as a Locus Influencing Pediatric BMI

(2009) J. Zhao et al.   DIABETES

Genetic Variants of the ENPP1/PC-1 Gene Are Associated With Hypertriglyceridemia in Male Subjects

(2009) Sinan Tanyolaç et al.   Metabolic Syndrome and Related Disorders

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Large, rare chromosomal deletions associated with severe early-onset obesity

(2009) Elena G. Bochukova et al.   NATURE

Inactivation of the Fto gene protects from obesity

(2009) Julia Fischer et al.   NATURE

The genetic contribution to non-syndromic human obesity

(2009) Andrew J. Walley et al.   NATURE REVIEWS GENETICS

A Rare Variant in the Visfatin Gene (NAMPT/PBEF1) Is Associated With Protection From Obesity

(2009) Alexandra I.F. Blakemore et al.   Obesity

Missing Heritability and GWAS Utility

(2009) Clifton Bogardus   Obesity

A Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels

(2009) J. Brent Richards et al.   PLoS Genetics

A Mouse Model for the Metabolic Effects of the Human Fat Mass and Obesity Associated FTO Gene

(2009) Chris Church et al.   PLoS Genetics

A novel association of a polymorphism in the first intron of adiponectin gene with type 2 diabetes, obesity and hypoadiponectinemia in Asian Indians

(2008) Karani S. Vimaleswaran et al.   HUMAN GENETICS

Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations

(2008) Michael Benzinou et al.   HUMAN MOLECULAR GENETICS

Leptin-Receptor Polymorphisms Relate to Obesity through Blunted Leptin-Mediated Sympathetic Nerve Activation in a Caucasian Male Population

(2008) Kazuko MASUO et al.   HYPERTENSION RESEARCH

Leptin Gene and Leptin Receptor Gene Polymorphisms Are Associated with Sweet Preference and Obesity

(2008) Einosuke MIZUTA et al.   HYPERTENSION RESEARCH

INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese

(2008) Kikuko Hotta et al.   JOURNAL OF HUMAN GENETICS

Common nonsynonymous variants in PCSK1 confer risk of obesity

(2008) Michael Benzinou et al.   NATURE GENETICS

Common variants near MC4R are associated with fat mass, weight and risk of obesity

(2008) Ruth J F Loos et al.   NATURE GENETICS

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

(2008) Gudmar Thorleifsson et al.   NATURE GENETICS

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

(2008) Cristen J Willer et al.   NATURE GENETICS

Viral AlkB proteins repair RNA damage by oxidative demethylation

(2008) Erwin van den Born et al.   NUCLEIC ACIDS RESEARCH

Association Analysis of the FTO Gene with Obesity in Children of Caucasian and African Ancestry Reveals a Common Tagging SNP

(2008) Struan F. A. Grant et al.   PLoS One