期刊
INOSITOL PHOSPHOLIPID SIGNALING IN PHYSIOLOGY AND DISEASE
卷 1280, 期 -, 页码 1-5出版社
BLACKWELL SCIENCE PUBL
DOI: 10.1111/nyas.12036
关键词
PI3K; breast cancer; PTEN; 4-phosphatase; INPP4B
类别
资金
- National Health and Medical Research Council [606621]
The PI3K/Akt signaling pathway is frequently increased in many human cancers, including breast cancer. Recent studies have identified INPP4B, which inhibits PI3K signaling, as an emerging tumor suppressor in breast cancer. This short review discusses these issues and the possibility that INPP4B is an important regulator in many cancers.
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