Physiological functions of GPx2 and its role in inflammation-triggered carcinogenesis

A crucial role for Nox 1 in redox-dependent regulation of Wnt-β-catenin signaling

(2012) Seheli Kajla et al.   FASEB JOURNAL

Glutathione peroxidase-3 produced by the kidney binds to a population of basement membranes in the gastrointestinal tract and in other tissues

(2011) Raymond F. Burk et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Basic Principles and Emerging Concepts in the Redox Control of Transcription Factors

(2011) Regina Brigelius-Flohé et al.   ANTIOXIDANTS & REDOX SIGNALING

High-Resolution Imaging of Selenium in Kidneys: A Localized Selenium Pool Associated with Glutathione Peroxidase 3

(2011) Mikalai Malinouski et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply

(2011) Susanne Krehl et al.   CARCINOGENESIS

Two Endoplasmic Reticulum PDI Peroxidases Increase the Efficiency of the Use of Peroxide during Disulfide Bond Formation

(2011) Van Dat Nguyen et al.   JOURNAL OF MOLECULAR BIOLOGY

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

(2011) Gina M. DeNicola et al.   NATURE

Two Tales of Antioxidant Enzymes on β Cells and Diabetes

(2010) Xin Gen Lei et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutathione Peroxidase-1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities

(2010) Edith Lubos et al.   ANTIOXIDANTS & REDOX SIGNALING

Loss of GPx2 increases apoptosis, mitosis, and GPx1 expression in the intestine of mice

(2010) Simone Florian et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive oxygen species in cancer

(2010) Geou-Yarh Liou et al.   FREE RADICAL RESEARCH

Glutathione peroxidases in different stages of carcinogenesis

(2009) Regina Brigelius-Flohé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Catalytic mechanisms and specificities of glutathione peroxidases: Variations of a basic scheme

(2009) Stefano Toppo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Transgenic mouse models for the vital selenoenzymes cytosolic thioredoxin reductase, mitochondrial thioredoxin reductase and glutathione peroxidase 4

(2009) Marcus Conrad   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Four selenoproteins, protein biosynthesis, and Wnt signalling are particularly sensitive to limited selenium intake in mouse colon

(2009) Anna Kipp et al.   MOLECULAR NUTRITION & FOOD RESEARCH

GPx2 Counteracts PGE2 Production by Dampening COX-2 and mPGES-1 Expression in Human Colon Cancer Cells

(2008) Antje Banning et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutathione Peroxidase 2 Inhibits Cyclooxygenase-2-Mediated Migration and Invasion of HT-29 Adenocarcinoma Cells but Supports Their Growth as Tumors in Nude Mice

(2008) A. Banning et al.   CANCER RESEARCH

Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

(2008) Alexander Seiler et al.   Cell Metabolism

The Antioxidant Defense System Keap1-Nrf2 Comprises a Multiple Sensing Mechanism for Responding to a Wide Range of Chemical Compounds

(2008) M. Kobayashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Dual roles of Nrf2 in cancer

(2008) A LAU et al.   PHARMACOLOGICAL RESEARCH