期刊
ANIMAL MODELS: THEIR VALUE IN PREDICTING DRUG EFFICACY AND TOXICITY
卷 1245, 期 -, 页码 11-13出版社
BLACKWELL SCIENCE PUBL
DOI: 10.1111/j.1749-6632.2011.06342.x
关键词
burrowing; chronic pain; rat
We propose that predictive validity of tests for analgesia may be improved by looking to reinstate specific, innate behaviors suppressed by pain, e. g., burrowing, because effective plasma concentrations in the rat are closer to effective clinical plasma concentrations than those generally used in rodent reflex withdrawal assays.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据