Review
Food Science & Technology
Ruben Fernandez-Rodriguez, Vicente Martinez-Vizcaino, Arthur E. Mesas, Blanca Notario-Pacheco, Maria Medrano, Leonie K. Heilbronn
Summary: Intermittent fasting (IF) has positive effects on depression scores in the general population, but does not significantly affect anxiety or mood state.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Nutrition & Dietetics
Qing Zhang, Caishun Zhang, Haidan Wang, Zhengye Ma, Defeng Liu, Xiaohan Guan, Yixin Liu, Yanwen Fu, Mingxuan Cui, Jing Dong
Summary: This study conducted a systematic review and meta-analysis to compare the effectiveness of intermittent fasting (IF) and continuous calorie restriction (CCR) in overweight and obese individuals. The results suggest that IF may be superior to CCR for weight loss in some aspects.
Review
Dentistry, Oral Surgery & Medicine
Sameena Parveen
Summary: Scientific evidence suggests that calorie restriction and intermittent fasting are effective strategies for controlling inflammation and lifestyle-related diseases. Studies have shown that calorie restriction may reduce inflammation and tissue damage associated with periodontitis, but more research is needed in human subjects. Additionally, incorporating these dietary interventions into society remains challenging due to the prevalence of obesity.
PERIODONTOLOGY 2000
(2021)
Review
Biochemistry & Molecular Biology
Anubhav Mishra, Devika Sobha, Dimple Patel, Padmanaban S. Suresh
Summary: This study aims to delve into the biological responses to intermittent fasting, examine the disease-modifying and cognitive effects of intermittent fasting, and shed light on the potential side effects.
ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Endocrinology & Metabolism
Amrendra Mishra, Hamed Mirzaei, Novella Guidi, Manlio Vinciguerra, Alice Mouton, Marina Linardic, Francesca Rappa, Rosario Barone, Gerardo Navarrete, Min Wei, Sebastian Brandhorst, Stefano Di Biase, Todd E. Morgan, S. Ram Kumar, Peter S. Conti, Matteo Pellegrini, Michel Bernier, Rafael de Cabo, Valter D. Longo
Summary: Research shows that a monthly cycle of 5 days of a fasting-mimicking diet can prevent obesity and related detrimental effects on cardiometabolic health and lifespan in mice. The fasting-mimicking diet inhibits obesity by reducing fat accumulation and improves heart function and resistance to cardiotoxins. It also prevents issues like hyperglycemia, hypercholesterolemia, and hyperleptinemia, while improving glucose and insulin tolerance.
Article
Endocrinology & Metabolism
Bo Liu, Amy T. Hutchison, Campbell H. Thompson, Kylie Lange, Gary A. Wittert, Leonie K. Heilbronn
Summary: Intermittent fasting (IF) has different effects on lipid metabolism compared to caloric restriction (CR), leading to more weight and fat loss, but also reduced expression of antioxidant enzymes. However, fasting can cause insulin resistance and increased PLIN5 expression, possibly reflecting transient lipid storage.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Review
Medicine, General & Internal
Mohammed Allaf, Hussein Elghazaly, Omer G. Mohamed, Mohamed Firas Khan Fareen, Sadia Zaman, Abdul-Majeed Salmasi, Kostas Tsilidis, Abbas Dehghan
Summary: Cardiovascular disease is a leading cause of death globally, with lifestyle changes like increased physical activity and healthy diets being key for prevention. Intermittent fasting has shown some benefits and is being researched for its role in reducing the risk of CVD.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Review
Geriatrics & Gerontology
Eleonora Duregon, Laura C. D. D. Pomatto-Watson, Michel Bernier, Nathan L. Price, Rafael de Cabo
Summary: Calorie restriction (CR) is a dietary manipulation that can increase health and longevity, and recently, the length and periodicity of daily fasting have emerged as potential drivers behind beneficial health effects. Numerous strategies and eating patterns have been successfully developed to recapitulate the benefits of CR.
Article
Critical Care Medicine
Wei Yuan, Xin He, Didier Morin, Gregory Barriere, Xuan Liu, Jiatong Li, Yue Zhu
Summary: The study found that intermittent fasting can improve neuronal survival and behavioral performance after acute SCI in rats by regulating the autophagy pathway. Intermittent fasting inhibited the apoptosis pathway and increased autophagic processes, while activating the AMPK/mTOR pathway and enhancing lysosome function.
JOURNAL OF NEUROTRAUMA
(2021)
Review
Nutrition & Dietetics
Joana M. Correia, Ines Santos, Pedro Pezarat-Correia, Analiza M. Silva, Goncalo V. Mendonca
Summary: The study found that non-Ramadan intermittent fasting can effectively reduce body weight, body mass index, and absolute fat mass, while Ramadan intermittent fasting, despite being accompanied by dehydration, can also effectively reduce body weight and relative fat mass. Overall, non-Ramadan intermittent fasting appears to be more effective in improving overall body composition.
FRONTIERS IN NUTRITION
(2021)
Review
Endocrinology & Metabolism
Kafi N. Ealey, Joy Phillips, Hoon-Ki Sung
Summary: Obesity is strongly associated with an increased risk of severe illness and death from COVID-19, as the physiological changes caused by elevated body weight lead to metabolic dysfunction and chronic inflammation, making individuals more vulnerable to complications from the virus. Efforts to address lifestyle changes and boost metabolic health and immunity are crucial in reducing the impact of obesity on COVID-19 morbidity and mortality.
TRENDS IN ENDOCRINOLOGY AND METABOLISM
(2021)
Article
Nutrition & Dietetics
Junren Kang, Xiaodong Shi, Ji Fu, Hailong Li, Enling Ma, Wei Chen
Summary: This retrospective cohort study evaluated the efficacy of intermittent fasting 5:2 plus program in Chinese patients with overweight or obesity. The results showed that the intermittent fasting 5:2 plus group achieved the highest weight loss compared to the daily calorie restriction group and the meal replacement group.
Article
Nutrition & Dietetics
Alex Brocchi, Eleni Rebelos, Angela Dardano, Michele Mantuano, Giuseppe Daniele
Summary: Intermittent fasting (IF) has been found to have beneficial effects on brain metabolism, enhancing cellular stress resistance, synaptic plasticity, and neurogenesis. However, further research is needed to understand the different IF protocols and long-term effects on brain metabolism before it can be widely prescribed for patients.
Article
Multidisciplinary Sciences
Mary Priyanka Udumula, Harshit Singh, Faraz Rashid, Laila Poisson, Nivedita Tiwari, Irina Dimitrova, Miriana Hijaz, Radhika Gogoi, Margaret Swenor, Adnan Munkarah, Shailendra Giri, Ramandeep Rattan
Summary: In a study on mice with epithelial ovarian cancer (EOC), it was found that 16-hour intermittent fasting (IF) can inhibit tumor growth and enhance anti-tumor immune response. IF alters anti-cancer immunity by increasing CD4(+) and CD8(+) cells, Th1 and cytotoxic responses.
Article
Oncology
Katherine K. Clifton, Cynthia X. Ma, Luigi Fontana, Lindsay L. Peterson
Summary: Intermittent fasting (IF) has gained popularity as a potential anticarcinogenic strategy, but its effects on cancer patients remain unclear without high-quality randomized clinical trials. More research is needed to determine the risks and benefits of IF for cancer patients before it can be recommended outside of clinical trials.
CA-A CANCER JOURNAL FOR CLINICIANS
(2021)