Article
Oncology
Denise Mattar, Antonio Di Filippo, Alessandra Invento, Davide Radice, Marius Burcuta, Vincenzo Bagnardi, Francesca Magnoni, Giorgia Santomauro, Giovanni Corso, Giovanni Mazzarol, Giuseppe Viale, Virgilio Sacchini, Viviana Galimberti, Paolo Veronesi, Mattia Intra
Summary: Application of the Z0011 criteria to patients undergoing breast-conserving therapy at our institution results in more than half a million Euro cost savings, without affecting locoregional recurrence or overall survival rates.
Article
Oncology
Eduardo Camargo Millen, Francisco Pimentel Cavalcante, Felipe Zerwes, Guilherme Novita, Alessandra Borba Anton de Souza, Joao Henrique Penna Reis, Helio Rubens de Oliveira Filho, Luciana Naira de B. L. Limongi, Barbara Pace Silva de Assis Carvalho, Adriana Magalhaes de Oliveira Freitas, Monica Travassos Jourdan, Vilmar Marques de Oliveira, Ruffo Freitas-Junior
Summary: The study evaluated the impact of the ACOSOG Z0011 trial on axillary breast cancer surgery management in Brazil, showing substantial changes in the management of axillary surgery in cN0/pathologically positive SLN cases, especially following publication of the updated Z11 results and similar studies. Factors such as better education environment and long-term follow-up were associated with the incorporation of Z11-related changes in practice.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Review
Medicine, General & Internal
Lydia Choi, Kimberly Ku, Wei Chen, Awni D. Shahait, Steve Kim
Summary: This study found that at least one-quarter of patients with positive preoperative axillary needle biopsies may potentially only require sentinel lymph node biopsy instead of axillary lymph node dissection.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Surgery
Katelyn A. Young, Samantha M. Lee, Matthew D. Adams, Christie L. Buonpane, Sarah A. Hayek, Mohsen M. Shabahang, David A. Rogers
Summary: This study analyzed 98 ACS presidential addresses between 1913 and 2019, identifying personal characteristics essential for success in surgery, including sincere compassion for patients, integrity, engagement in shaping changes, and commitment to lifelong learning. Recently, humility, inclusivity, and the ability to be a collaborative team leader have been recognized as important interpersonal attributes for success.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2021)
Article
Surgery
Jayson S. Marwaha, Brendin R. Beaulieu-Jones, Margaret Berrigan, William Yuan, Stephen R. Odom, Charles H. Cook, Benjamin B. Scott, Alok Gupta, Charles S. Parsons, Anupamaa J. Seshadri, Gabriel A. Brat
Summary: This study compared the predictive utility of surgeon intuition and a risk calculator derived from ACS NSQIP in predicting postoperative complications. The results showed that preoperative surgeon intuition alone was not an effective predictor, while the risk calculator based on ACS NSQIP was more accurate. Combining surgeon intuition with clinical data did not enhance the prediction.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2023)
Article
Oncology
Sarah M. DeSnyder, Min Yi, Francesco Boccardo, Sheldon Feldman, V. Suzanne Klimberg, Mark Smith, Paul T. R. Thiruchelvam, Sarah McLaughlin
Summary: The majority of ASBrS members were unfamiliar with expert recommendations for breast cancer-related lymphedema (BCRL), however, they emphasized on educating patients and conducting BCRL screenings. There are opportunities to increase awareness around best practices and acquire technical expertise in ARM and LYMPHA.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Surgery
Alana Hofmann, Huazhi Liu, Edward Copeland, Darwin Ang
Summary: This study evaluates the impact of different facility types on survival and mortality outcomes for breast cancer patients, and finds that community programs benefit the most. The Z0011 trial has a positive influence on both community and academic facilities.
Article
Oncology
Emilia J. Diego, Laura H. Rosenberger, Xiaoyan Deng, Kandace P. McGuire
Summary: Phyllodes tumors (PTs) are rare breast neoplasms with variable clinical behavior by histologic type. A survey of American Society of Breast Surgeon members found that management patterns for PTs are evolving but still vary, indicating the need for more specific management guidelines by subtype given differences in clinical behavior.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Oncology
Chihwan Cha, Eun Young Kim, Sung Yong Kim, Jai Min Ryu, Min Ho Park, Seokwon Lee, Young-Jin Suh, Nayeon Choi, Hanpyo Hong, Hyung Suk Kim, Min Sung Chung
Summary: This study investigated the time trend of axillary surgery in Asian patients with breast cancer and found a downward trend in the proportion of axillary lymph node dissection (ALND) in Korean patients. However, the rate of decrease was slower than in the Dutch cohort.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2022)
Article
Surgery
Juliet Emamaullee, Tiffany Lian, Stacy Moroz, Brian Zuckerbraun, Jeffrey Matthews, Ankush Gosain
Summary: This study retrospectively reviewed the profiles of applicants for the Jacobson Promising Investigator Award (JPIA) administered by the American College of Surgeons. The findings showed that selection for the JPIA is associated with previous extramural NIH K award, a higher number of publications, and higher h-Index and m-quotient. Receipt of the JPIA is associated with a high rate of subsequent NIH R01 funding and publication metrics.
Article
Surgery
Deborah A. Kuhls, Brendan T. Campbell, Arielle Thomas, Holly Michaels, Eileen M. Bulger, Ronald M. Stewart
Summary: A survey of US members of the American College of Surgeons (ACS) revealed broad support for initiatives related to firearm injury prevention, with varying degrees of support based on specific initiatives and demographic characteristics. The results align with the ACS strategy of healthcare professionals working together to understand and address the root causes of violence, and promoting safe firearm ownership.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2021)
Article
Oncology
Abida K. Sattar, Hania Shahzad, Taleaa Masroor, Russell Seth Martins, Nida Zahid, Farin F. Amersi
Summary: This study surveyed members of the American Society of Breast Surgeons to understand their practice patterns of antibiotic prophylaxis after mastectomy. The results showed that there is wide variation in postoperative antibiotic use depending on whether reconstruction is performed and whether indwelling drains are present.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Orthopedics
Michelle Xiao, Seth L. Sherman, Marc R. Safran, Geoffrey D. Abrams
Summary: The survey revealed that 37.9% of ACL study group members currently use vancomycin to pre-soak ACL tendon grafts to reduce post-operative infection risk, with the majority of surgeons having adopted this practice within the past 5 years. The main concern regarding using vancomycin was the mechanical properties of the graft after soaking.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2021)
Article
Oncology
Nobuyoshi Kittaka, Satomi Nakajima, Takaaki Hatano, Yukiko Seto, Hiroki Kusama, Saki Matsui, Minako Nishio, Fumie Fujisawa, Keiichiro Honma, Takahiro Nakayama, Yasuhiro Tamaki
Summary: The study found that only a small proportion of early breast cancer patients required ALND due to three or more metastatic SLNs according to the Z0011 criteria, with intraoperative assessment having low sensitivity.
Article
Surgery
Nicholas R. Sinclair, Andrew Kochuba, Demetrius M. Coombs, Rafael A. Couto, Ali H. Charafeddine, Jacob Grow, Alan Matarasso, James E. Zins
Summary: This article presents the current face lift practice patterns among American Society of Plastic Surgeons members and compares them to previous patterns. The results show that while the basic approach to face lift surgery has not changed significantly in the past 20 years, there have been positive developments in operative adjuncts.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Editorial Material
Oncology
Lauren M. Postlewait, Anthony Lucci
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
Natalia Partain, Lauren M. Postlewait, Mediget Teshome, Kelly Rosso, Carolyn Hall, Juhee Song, Salyna Meas, Sarah M. DeSnyder, Bora Lim, Vicente Valero, Wendy Woodward, Naoto T. Ueno, Henry Kuerer, Anthony Lucci
Summary: In this retrospective study, MRM in de novo stage IV IBC patients is an independent factor associated with improved OS. Our findings strongly support the need for prospective randomized trials evaluating possible survival benefits of MRM in de novo stage IV IBC patients.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
Michael G. White, Andrew Lee, Diego Vicente, Carolyn Hall, Michael P. Kim, Matthew H. G. Katz, Jeffrey E. Lee, Naruhiko Ikoma, Anthony Lucci, Ching-Wei D. Tzeng
Summary: This study investigated the safety and feasibility of intraoperative portal vein blood (PVB) collection during pancreatic ductal adenocarcinoma (PDAC) resection. PVB circulating tumor cell (CTC) counts were significantly correlated with overall survival (OS), providing a potential new avenue for future research and clinical treatment.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
Devarati Mitra, Gabriel Ologun, Emily Z. Keung, Ryan P. Goepfert, Rodabe N. Amaria, Merrick I. Ross, Jeffrey E. Gershenwald, Anthony Lucci, Sarah B. Fisher, Michael A. Davies, Jeffrey E. Lee, Andrew J. Bishop, Ahsan S. Farooqi, Jennifer Wargo, B. Ashleigh Guadagnolo
Summary: This study found that nodal recurrence is the primary driver of early disease relapse for patients with SLN-positive melanoma who do not undergo CLND. Patients with LVI, two or more involved nodes, or > 1 mm nodal disease are at particularly high risk of nodal relapse.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
Leisha C. Elmore, Henry M. Kuerer, Carlos H. Barcenas, Benjamin D. Smith, Makesha Miggins, Anthony Lucci, Abigail S. Caudle, Funda Meric-Bernstam, Kelly K. Hunt, Mediget Teshome
Summary: For breast cancer patients receiving NST and experiencing disease progression, the study found a high proportion of patients died and developed distant metastasis. Triple-negative breast cancer patients had a higher risk of death. Despite surgical management, survival rates were still poor.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Editorial Material
Oncology
Lauren M. Postlewait, Anthony Lucci
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
Taiwo Adesoye, Oluwatowo Babayemi, Lauren M. Postlewait, Sarah M. DeSnyder, Susie X. Sun, Wendy A. Woodward, Naoto T. Ueno, Kelly K. Hunt, Anthony Lucci, Mediget Teshome
Summary: This study evaluated the age-related differences in patients with inflammatory breast cancer (IBC) and found no significant disparities in demographics, treatment patterns, or clinical outcomes between patients aged 40 years or younger and those aged 65 years or older. These findings do not support age-related treatment de-escalation in IBC.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
Taiwo Adesoye, Anthony Lucci
Summary: Inflammatory breast cancer is a rare and aggressive form of breast cancer that requires diagnosis and treatment based on clinical symptoms, with no evidence supporting de-escalation of surgical therapy. Delayed reconstruction is recommended to avoid recurrence and potential delays in adjuvant therapy.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
Lauren M. Postlewait, Mediget Teshome, Taiwo Adesoye, Sarah M. DeSnyder, Bora Lim, Henry M. Kuerer, Isabelle Bedrosian, Susie X. Sun, Wendy A. Woodward, Huong T. Le-Petross, Vicente Valero, Naoto T. Ueno, Anthony Lucci
Summary: Inflammatory breast cancer (IBC) patients have a high rate of de novo stage IV disease, with approximately 8.3% presenting with contralateral axillary metastasis (CAM) at diagnosis. CAM was best detected with ultrasound and PET imaging. Routine contralateral axillary ultrasound is recommended for staging all IBC patients to facilitate early diagnosis and guide future clinical trials for CAM management and outcomes.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
Lyndsey J. Kilgore, Brittany L. Murphy, Lauren M. Postlewait, Diana H. Liang, Isabelle Bedrosian, Anthony Lucci, Henry M. Kuerer, Kelly K. Hunt, Mediget Teshome
Summary: This study evaluated the impact of the COVID-19 pandemic on 2019-2020 Breast Surgical Oncology fellows, finding that clinical experience was altered while operative experience remained largely unaffected. Some fellows delayed general surgery board examinations due to the pandemic and experienced increased stress levels.
JOURNAL OF SURGICAL ONCOLOGY
(2021)
Editorial Material
Biochemistry & Molecular Biology
Dhruvajyoti Roy, Anthony Lucci, Michail Ignatiadis, Stefanie S. Jeffrey
TRENDS IN MOLECULAR MEDICINE
(2021)
Editorial Material
Dermatology
Yuling Wang, Vijaya Ramachandran, Dawen Sui, Kejing Xu, Lauren E. Haydu, Shenying Fang, Jennifer L. McQuade, Sarah B. Fisher, Anthony Lucci, Emily Z. Keung, Jennifer Wargo, Jeffrey E. Gershenwald, Merrick I. Ross, Jeffrey E. Lee
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2022)
Article
Oncology
Balraj Singh, Vanessa N. Sarli, Anthony Lucci
Summary: Using a cell culture model, researchers found that JIB-04 can sensitize resistant breast cancer cells to chemotherapy drugs and increase the expression of PD-L1 in cancer cells, which may have clinical applications in improving the treatment of triple-negative breast cancer.
Review
Biochemistry & Molecular Biology
Sridevi Addanki, Salyna Meas, Vanessa Nicole Sarli, Balraj Singh, Anthony Lucci
Summary: Liquid biopsies are a non-invasive method for detecting cancer biomarkers through a simple blood draw. These circulating markers have significant prospects in evaluating patients' prognosis, monitoring therapy response, and developing precision medicine.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Oncology
Balraj Singh, Vanessa N. Sarli, Ryan D. Milligan, Hannah E. Kinne, Anna Shamsnia, Laura J. Washburn, Sridevi Addanki, Anthony Lucci
Summary: We treated highly metabolically adaptable triple-negative inflammatory breast cancer cells with JQ1 and found that it inhibited therapy-resistant cells. Although JQ1 couldn't kill these resistant cells, it sensitized them to treatment with doxorubicin and paclitaxel. Additionally, JQ1 reduced PD-L1 protein levels, indicating a potential improvement in immunotherapy response.