Article
Gastroenterology & Hepatology
Celia R. Keane, Greg O'Grady, Ian P. Bissett, Julian L. Hayes, Mike Hulme-Moir, Tim W. Eglinton, Michael J. Solomon, John W. Lumley, John Simes, Andrew R. L. Stevenson
Summary: Low anterior resection syndrome has a significant impact on the quality of life in rectal cancer survivors. This study found that there is no difference in the functional outcome between patients undergoing laparoscopic versus open resection for rectal adenocarcinoma, suggesting that the choice of surgical approach does not influence the likelihood or severity of low anterior resection syndrome.
DISEASES OF THE COLON & RECTUM
(2022)
Article
Oncology
Chi Kin Law, Kate Brewer, Chris Brown, Kate Wilson, Lisa Bailey, Wendy Hague, John R. Simes, Andrew Stevenson, Michael Solomon, Rachael L. Morton
Summary: The study found that factors such as full-time employment presurgery and the presence of metastatic disease can predict the return to work status at 12 months. Additionally, a laparoscopic surgical approach to rectal cancer may increase the likelihood of returning to work.
Article
Surgery
Rebecca Mercieca-Bebber, Renee Eggins, Kilian Brown, Val J. Gebski, Kate Brewer, Lenna Lai, Lisa Bailey, Michael J. Solomon, John W. Lumley, Peter Hewett, Andrew D. Clouston, Kate Wilson, Wendy Hague, Julian Hayes, Stephen White, Matt Morgan, R. John Simes, Andrew R. L. Stevenson
Summary: This study aimed to compare the urinary, bowel, and sexual functioning of rectal cancer patients who underwent open or laparoscopic surgery. The results showed that patients who underwent open surgery had fewer symptoms in bowel and sexual functioning. However, it remains difficult to recommend one surgical approach over the other for rectal resection.
Article
Oncology
Wen Hui Lim, Darren Jun Hao Tan, Cheng Han Ng, Nicholas Syn, Bee Choo Tai, Tianyuan Gu, Jieling Xiao, Yip Han Chin, Zachariah Gene Wing Ow, Neng Wei Wong, Fung Joon Foo, Andrew C. Lynch, Brendan John Moran, Choon Seng Chong
Summary: This meta-analysis concludes that laparoscopic rectal cancer resection does not compromise long-term oncologic outcomes compared with open surgery, with potential survival benefits for a minimal access approach in patients with stage II and III rectal cancer.
Article
Surgery
Yanfei Lin
Summary: A large population-based nomogram incorporating log odds of positive nodes (LODDS) was developed in this study to predict the overall survival (OS) of stage II/III rectal cancer patients treated with neoadjuvant chemoradiotherapy (NCRT) followed by surgical resection. The nomogram showed a satisfactorily discriminative and stable ability to predict the OS for those patients.
Article
Oncology
Wenquan Ou, Xiaohua Wu, Jinfu Zhuang, Yuanfeng Yang, Yiyi Zhang, Xing Liu, Guoxian Guan
Summary: This study compared the efficacy of different approaches for laparoscopic intersphincteric resection (LAISR) of low rectal cancer and discussed the surgical indications for each approach. The results showed that TAISR, TPAISR, and PAISR have unique advantages and do not differ in terms of operation safety, patient outcomes, or anal function. The choice of surgical approach should be based on specific conditions.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2022)
Article
Gastroenterology & Hepatology
Tomonori Akagi, Kentaro Nakajima, Yasumitsu Hirano, Tomoya Abe, Ryo Inada, Yohei Kono, Hidefumi Shiroshita, Tetsuji Ohyama, Masafumi Inomata, Seiichiro Yamamoto, Takeshi Naitoh, Yoshiharu Sakai, Masahiko Watanabe
Summary: This study evaluated the technical and oncological safety of laparoscopic surgery versus open surgery in obese patients with rectal cancer. The results showed that laparoscopic surgery had lower lymph node harvest and shorter postoperative hospital stay, but there was no significant difference in relapse-free survival between the two groups.
ANNALS OF GASTROENTEROLOGICAL SURGERY
(2023)
Article
Oncology
Xian Hua Gao, Bai Zhi Zhai, Juan Li, Jean Luc Tshibangu Kabemba, Hai Feng Gong, Chen Guang Bai, Ming Lu Liu, Shao Ting Zhang, Fu Shen, Lian Jie Liu, Wei Zhang
Summary: This study compared different definitions for upper rectal cancers and found that defining rectal cancer above the anterior peritoneal reflection (APR) may be the optimal way to reduce the need for postoperative adjuvant radiation therapy in stage II/III rectal cancer patients.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Hong Yang, Lei Chen, Xiuxiu Wu, Chenghai Zhang, Zhendan Yao, Jiadi Xing, Ming Cui, Beihai Jiang, Xiangqian Su
Summary: This study found that distant metastasis was more common than locoregional recurrence after laparoscopic resection of rectal cancer, and there were different clinicopathological factors associated with locoregional recurrence and distant metastasis. Involved circumferential resection margin and suboptimal lymph node yield were adverse surgery-related factors of tumor recurrence that should be paid more attention to during the operation.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Xuting Ran, Xinlin He, Zhengyu Li
Summary: This study evaluated the oncologic outcomes of laparoscopy and laparotomy in the management of early-stage ovarian cancer patients. The results showed that there is no difference in prognosis between laparoscopic and open surgery in women with stage I epithelial ovarian cancer. Laparoscopic treatment is safe and feasible for these patients.
FRONTIERS IN ONCOLOGY
(2022)
Article
Medicine, General & Internal
Meng Kong, Hongyuan Chen, Keshu Shan, Hongguang Sheng, Leping Li
Summary: A meta-analysis comparing laparoscopic and open surgery for rectal cancer showed similar disease-free survival (DFS) rates but significantly better overall survival (OS) rates in the laparoscopic group. These findings support the routine use of laparoscopic surgery for patients with rectal cancer.
Article
Oncology
Ke Nie, Peng Hu, Jianjun Zheng, Yang Zhang, Pengfei Yang, Salma K. Jabbour, Ning Yue, Xue Dong, Shufeng Xu, Bo Shen, Tianye Niu, Xiaotong Hu, Xiujun Cai, Jihong Sun
Summary: This study constructed a prognostic model using multiparametric MRI information to predict 5-year overall survival in advanced rectal cancer patients. The model outperformed conventional TNM staging and other clinical prognostic factors. The study highlighted the importance of multiparametric MRI in addressing long-term survival estimation in rectal cancer, and the radiomics signatures showed value in predicting 5-year overall survival for stage II-III rectal cancer.
FRONTIERS IN ONCOLOGY
(2022)
Article
Medicine, General & Internal
Ning Li, Yuan Zhu, Lu-Ying Liu, Yan-Ru Feng, Wen-Ling Wang, Jun Wang, Hao Wang, Gao-Feng Li, Yuan Tang, Chen Hu, Wen-Yang Liu, Hua Ren, Shu-Lian Wang, Wei-Hu Wang, Yong-Wen Song, Yue-Ping Liu, Hui Fang, Yu Tang, Ning-Ning Lu, Bo Chen, Shu-Nan Qi, Xin-Fan Liu, Ye-Xiong Li, Jing Jin
Summary: The addition of oxaliplatin to postoperative capecitabine-based chemoradiotherapy did not improve treatment efficacy but increased the risk of severe acute toxic effects. Postoperative capecitabine with radiotherapy plays a fundamental role in the treatment of locally advanced rectal cancer.
Article
Surgery
Fiorenzo Angehrn, Romano Schneider, Alexander Wilhelm, Diana Daume, Luca Koechlin, Lana Fourie, Markus von Flue, Beatrice Kern, Daniel C. Steinemann, Martin Bolli
Summary: This study compared the outcomes of robotic-assisted and laparoscopic-assisted surgery for rectal cancer after neoadjuvant chemoradiotherapy (nCRT). The study found that robotic-assisted surgery had lower conversion to open surgery, lower stomata creation rate, and similar postoperative morbidity compared to laparoscopic surgery. Although the operation time was longer in the robotic group, this difference was not significant in patients with higher BMI.
JOURNAL OF ROBOTIC SURGERY
(2022)
Article
Surgery
Caroline D. M. Witjes, Abhilashaben S. Patel, Aniruddh Shenoy, Stephen Boyce, James E. East, Christopher Cunningham
Summary: The study investigated the efficacy of local treatments and traditional surgery in patients with early rectal cancer, showing that EMR/ESD and TEM/TAMIS can achieve good oncological outcomes in selected patients.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)