Activity of temozolomide in patients with advanced chemorefractory colorectal cancer and MGMT promoter methylation

Targeted therapy in metastatic colorectal cancer – An example of personalised medicine in action

(2013) V. Heinemann et al.   CANCER TREATMENT REVIEWS

Promoter CpG Island Hypermethylation of the DNA Repair Enzyme MGMT Predicts Clinical Response to Dacarbazine in a Phase II Study for Metastatic Colorectal Cancer

(2013) A. Amatu et al.   CLINICAL CANCER RESEARCH

A Phase II Study of Temozolomide in Patients with Advanced Aerodigestive Tract and Colorectal Cancers and Methylation of the O6-Methylguanine-DNA Methyltransferase Promoter

(2013) D. Hochhauser et al.   MOLECULAR CANCER THERAPEUTICS

Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial

(2012) Axel Grothey et al.   LANCET

Frequent mutations of KRAS in addition to BRAF in colorectal serrated adenocarcinoma

(2011) Karoliina Stefanius et al.   HISTOPATHOLOGY

Response to Temozolomide in Patients With Metastatic Colorectal Cancer With Loss of MGMT Expression: A New Approach in the Era of Personalized Medicine?

(2011) Einat Shacham-Shmueli et al.   JOURNAL OF CLINICAL ONCOLOGY

MEK-ERK Signaling Dictates DNA-Repair Gene MGMT Expression and Temozolomide Resistance of Stem-Like Glioblastoma Cells via the MDM2-p53 Axis

(2011) Atsushi Sato et al.   STEM CELLS

Pilot Study Using Molecular Profiling of Patients' Tumors to Find Potential Targets and Select Treatments for Their Refractory Cancers

(2010) Daniel D. Von Hoff et al.   JOURNAL OF CLINICAL ONCOLOGY

MSH6 Mutations Arise in Glioblastomas during Temozolomide Therapy and Mediate Temozolomide Resistance

(2009) S. Yip et al.   CLINICAL CANCER RESEARCH

PDGFRA, PDGFRB, EGFR, and downstream signaling activation in malignant peripheral nerve sheath tumor

(2009) Federica Perrone et al.   NEURO-ONCOLOGY

PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients

(2008) F. Perrone et al.   ANNALS OF ONCOLOGY

A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer

(2008) O A Khan et al.   BRITISH JOURNAL OF CANCER