期刊
ANNALS OF ONCOLOGY
卷 23, 期 -, 页码 135-138出版社
OXFORD UNIV PRESS
DOI: 10.1093/annonc/mds313
关键词
cancer stem cells; genomics; pancreatic cancer; stroma
类别
资金
- Celgene, Inc.
Pancreatic cancer remains a devastating disease. Over the last few years, there have been important advances in the molecular and biological understanding of pancreatic cancer. This included understanding of the genomic complexity of the disease, the role of pancreatic cancer stem cells, the relevance of the tumor microenvironment, and the unique metabolic adaptation of pancreas cancer cells to obtain nutrients under hypoxic environment. In this paper, we review the most salient developments in these few areas.
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