Current concepts and management of glioblastoma

Patterns of progression in patients with recurrent glioblastoma treated with bevacizumab

(2011) W. B. Pope et al.   NEUROLOGY

Bevacizumab does not increase the risk of remote relapse in malignant glioma

(2010) Antje Wick et al.   ANNALS OF NEUROLOGY

Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma

(2010) Houtan Noushmehr et al.   CANCER CELL

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Temozolomide Versus Procarbazine, Lomustine, and Vincristine in Recurrent High-Grade Glioma

(2010) Michael Brada et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase III Study of Enzastaurin Compared With Lomustine in the Treatment of Recurrent Intracranial Glioblastoma

(2010) Wolfgang Wick et al.   JOURNAL OF CLINICAL ONCOLOGY

Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed Glioblastoma

(2010) John H. Sampson et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase II Study of Cediranib, an Oral Pan–Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Recurrent Glioblastoma

(2010) Tracy T. Batchelor et al.   JOURNAL OF CLINICAL ONCOLOGY

Radiographic patterns of relapse in glioblastoma

(2010) Marc C. Chamberlain   JOURNAL OF NEURO-ONCOLOGY

A Phase II study of anti–epidermal growth factor receptor radioimmunotherapy in the treatment of glioblastoma multiforme

(2010) Linna Li et al.   JOURNAL OF NEUROSURGERY

Monoclonal antibody specific for IDH1 R132H mutation

(2009) David Capper et al.   ACTA NEUROPATHOLOGICA

Molecularly targeted therapies for glioma

(2009) Ryuya Yamanaka et al.   ANNALS OF NEUROLOGY

Multicentre phase II studies evaluating imatinib plus hydroxyurea in patients with progressive glioblastoma

(2009) D A Reardon et al.   BRITISH JOURNAL OF CANCER

Genetic alterations and signaling pathways in the evolution of gliomas

(2009) Hiroko Ohgaki et al.   CANCER SCIENCE

Signaling in Malignant Astrocytomas: Role of Neural Stem Cells and Its Therapeutic Implications

(2009) S. R. Alcantara Llaguno et al.   CLINICAL CANCER RESEARCH

Antiepileptic Drug Monotherapy: The Initial Approach in Epilepsy Management

(2009) Erik St. Louis et al.   Current Neuropharmacology

Glioblastoma multiforme: a review of where we have been and where we are going

(2009) Cory Adamson et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Talampanel With Standard Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma: A Multicenter Phase II Trial

(2009) Stuart A. Grossman et al.   JOURNAL OF CLINICAL ONCOLOGY

D-Dimer and Prothrombin Fragment 1 + 2 Predict Venous Thromboembolism in Patients With Cancer: Results From the Vienna Cancer and Thrombosis Study

(2009) Cihan Ay et al.   JOURNAL OF CLINICAL ONCOLOGY

Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma

(2009) Henry S. Friedman et al.   JOURNAL OF CLINICAL ONCOLOGY

Randomized Phase II Trial of Erlotinib Versus Temozolomide or Carmustine in Recurrent Glioblastoma: EORTC Brain Tumor Group Study 26034

(2009) Martin J. van den Bent et al.   JOURNAL OF CLINICAL ONCOLOGY

Epilepsy in cerebral glioma: timing of appearance and histological correlations

(2009) Anna Rosati et al.   JOURNAL OF NEURO-ONCOLOGY

Imatinib in combination with hydroxyurea versus hydroxyurea alone as oral therapy in patients with progressive pretreated glioblastoma resistant to standard dose temozolomide

(2009) Gregor Dresemann et al.   JOURNAL OF NEURO-ONCOLOGY

The Austrian Brain Tumour Registry: a cooperative way to establish a population-based brain tumour registry

(2009) Adelheid Wöhrer et al.   JOURNAL OF NEURO-ONCOLOGY

The role of steroids in the management of brain metastases: a systematic review and evidence-based clinical practice guideline

(2009) Timothy C. Ryken et al.   JOURNAL OF NEURO-ONCOLOGY

Rechallenge with temozolomide in patients with recurrent gliomas

(2009) Antje Wick et al.   JOURNAL OF NEUROLOGY

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme

(2009) J. H. Sampson et al.   MOLECULAR CANCER THERAPEUTICS

Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility

(2009) Margaret Wrensch et al.   NATURE GENETICS

Genome-wide association study identifies five susceptibility loci for glioma

(2009) Sanjay Shete et al.   NATURE GENETICS

MGMT promoter methylation in malignant gliomas: ready for personalized medicine?

(2009) Michael Weller et al.   Nature Reviews Neurology

Operative techniques for gliomas and the value of extent of resection

(2009) Nader Sanai et al.   Neurotherapeutics

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

(2009) G L Semenza   ONCOGENE

Temozolomide rechallenge in recurrent malignant glioma by using a continuous temozolomide schedule

(2008) James R. Perry et al.   CANCER

HIF1α Induces the Recruitment of Bone Marrow-Derived Vascular Modulatory Cells to Regulate Tumor Angiogenesis and Invasion

(2008) Rose Du et al.   CANCER CELL

Integrin  v 3-Targeted Radioimmunotherapy of Glioblastoma Multiforme

(2008) A. Veeravagu et al.   CLINICAL CANCER RESEARCH

Safety profile of carmustine wafers in malignant glioma: a review of controlled trials and a decade of clinical experience

(2008) Michael Sabel et al.   CURRENT MEDICAL RESEARCH AND OPINION

Cilengitide: an integrin-targeting arginine–glycine–aspartic acid peptide with promising activity for glioblastoma multiforme

(2008) David A Reardon et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Correlation of O6-Methylguanine Methyltransferase (MGMT) Promoter Methylation With Clinical Outcomes in Glioblastoma and Clinical Strategies to Modulate MGMT Activity

(2008) Monika E. Hegi et al.   JOURNAL OF CLINICAL ONCOLOGY

Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma

(2008) Anastasia Murat et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase II Study of Imatinib in Patients With Recurrent Gliomas of Various Histologies: A European Organisation for Research and Treatment of Cancer Brain Tumor Group Study

(2008) Eric Raymond et al.   JOURNAL OF CLINICAL ONCOLOGY

Efficacy, safety and patterns of response and recurrence in patients with recurrent high-grade gliomas treated with bevacizumab plus irinotecan

(2008) R. M. Zuniga et al.   JOURNAL OF NEURO-ONCOLOGY

Toxicity from chemoradiotherapy in older patients with glioblastoma multiforme

(2008) Angelique E. Sijben et al.   JOURNAL OF NEURO-ONCOLOGY

A phase II clinical trial of poly-ICLC with radiation for adult patients with newly diagnosed supratentorial glioblastoma: a North American Brain Tumor Consortium (NABTC01-05)

(2008) Nicholas Butowski et al.   JOURNAL OF NEURO-ONCOLOGY

End of life issues in brain tumor patients

(2008) Andrea Pace et al.   JOURNAL OF NEURO-ONCOLOGY

The End-of-Life Hospital Setting in Patients with Glioblastoma

(2008) Stefan Oberndorfer et al.   JOURNAL OF PALLIATIVE MEDICINE

Psychosocial and supportive-care needs in high-grade glioma

(2008) Susan Catt et al.   LANCET ONCOLOGY

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE

Postoperative Treatment of Primary Glioblastoma Multiforme With Radiation and Concomitant Temozolomide in Elderly Patients

(2007) Stephanie E. Combs et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS