期刊
ANNALS OF BIOMEDICAL ENGINEERING
卷 43, 期 3, 页码 628-640出版社
SPRINGER
DOI: 10.1007/s10439-014-1145-y
关键词
Biomaterials; Immune cells; Vascularization
资金
- NIH [R01 DE013349, R01 HL069957]
- NSF GRFP [DGE1144152]
- Wyss Institute
There exists a critical need to develop strategies that promote blood vessel formation (neovascularization) in virtually all tissue engineering and regenerative medicine efforts. While research typically focuses on understanding and exploiting the role of angiogenic factors and vascular cells on new blood vessel formation, the activity of the immune system is being increasingly recognized to impact vascular formation and adaptation. This review will provide both an overview of the intersection of angiogenesis and the immune system, and how biomaterials may be designed to promote favorable interactions between these two systems to promote effective vascularization.
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