Article
Veterinary Sciences
Sofie Kromann, Rikke Heidemann Olsen, Anders Miki Bojesen, Henrik Elvang Jensen, Ida Thofner
Summary: Biomarkers of inflammation are valuable tools for health evaluation in various species. This study aimed to identify easily accessible biomarkers of infection in poultry by analyzing blood samples from experimentally infected and control hens using equipment available in veterinary clinics. The results showed that the equipment successfully differentiated between sick and healthy birds, demonstrating its potential as an easily added parameter for evaluation in research studies and as a valuable decision-making tool for poultry veterinarians.
VETERINARY RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Daniela Marasco, Caterina Vicidomini, Pawel Krupa, Federica Cioffi, Pham Dinh Quoc Huy, Mai Suan Li, Daniele Florio, Kerensa Broersen, Maria Francesca De Pandis, Giovanni N. Roviello
Summary: Different isoquinoline alkaloids exhibit varying effects on beta-amyloid aggregation, with some compounds showing inhibitory effects and others showing promoting effects. Experimental results suggest that these compounds have the potential to serve as starting leads for the development of therapeutic strategies in neurodegenerative diseases.
CHEMICO-BIOLOGICAL INTERACTIONS
(2021)
Article
Veterinary Sciences
Ali Hassanpour, Sina Moghaddam
Summary: This study demonstrates the usefulness of assessing the serum concentration of acute-phase proteins in the early diagnosis and treatment of Rhodococcus equi pneumonia in foals.
VETERINARY MEDICINE AND SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
L. Wollowski, W. Heuwieser, A. Kossatz, M. F. Addis, G. M. G. Puggioni, Laurent Meriaux, S. Bertulat
Summary: The timely and objective diagnosis and classification of mastitis is crucial, and analyzing specific biomarkers in milk can be advantageous in comparison to other criteria. The study aimed to investigate the diagnostic value of 3 biomarkers in detecting subclinical and clinical mastitis, showing the potential for reliable detection using cathelicidin, milk amyloid A, and haptoglobin measurements in milk.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Multidisciplinary Sciences
Wael El-Deeb, Mahmoud Fayez, Naser Alhumam, Ibrahim Elsohaby, Sayed A. Quadri, Hermine Mkrtchyan
Summary: Staphylococcal mastitis is a common and costly disease in dairy cows. This study found elevated levels of multiple biomarkers in cows with SM, serving as effective diagnostic tools. There was no significant difference in biomarker levels between mastitis caused by different pathogens.
Article
Veterinary Sciences
Virpi Sali, Christina Veit, Anna Valros, Sami Junnikkala, Mari Heinonen, Janicke Nordgreen
Summary: The study found that ADA and Hp in saliva can serve as inflammatory biomarkers in pigs, with saliva sampling being less stressful and easier than blood sampling. Further research in commercial settings with larger sample sizes is recommended.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Xuguang Lin, Kenichi Watanabe, Masahiro Kuragano, Kiyotaka Tokuraku
Summary: The study found that AEFs extracted and purified from different animal species (camel, cat, cattle, goat, and mouse) could promote mouse SAA protein aggregation in vitro, with mouse and cat AEFs showing higher mSAA aggregation-promoting activity than camel, cattle, and goat AEFs. This suggests that AA amyloidosis exhibits higher transmission activity among animals carrying genetically homologous SAA gene, providing a new understanding of the pathogenesis of amyloidosis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Multidisciplinary Sciences
Csilla Tothova, Oskar Nagy, Jaroslav Novotny, Katarina Vdoviakova, Lenka Kresakova, Jan Danko, Zdenek Zert, Lubomir Medvecky, Eva Petrovova
Summary: This study investigated the changes in inflammatory markers and enzyme activities following the repair of induced articular cartilage defects in pigs. The results suggest that SAA, Hp, CRP, and pig-MAP may be useful biomarkers for monitoring acute phase responses during the postoperative period.
Article
Microbiology
Ana S. Gonzalez-Mendez, Jorge L. Tortora Perez, Edith Rojas-Anaya, Hugo Ramirez Alvarez
Summary: The aim of this study was to investigate the genetic expression of antiretroviral restriction factors (ARF) and acute phase proteins (APP) in cattle with aleukemic (AL) and persistent lymphocytosis (PL), and their relationship with proviral and viral loads. Blood samples were collected from dairy cows, and the genetic material was extracted from peripheral blood leukocytes. The expression of ARF (APOBEC-Z1, Z2, and Z3; HEXIM-1, HEXIM-2, and BST2) and APP (haptoglobin (HP) and serum amyloid A (SAA)) was quantified using qPCR. Significant differences were observed in the expression of APOBEC-Z3 in BLV-infected animals. Strong expression of ARF genes was only found in the AL group. APOBEC (Z1 and Z3), HEXIM-1, and HEXIM-2 were more frequently identified in BLV-infected animals. HEXIM-2 showed active gene expression in the AL group. The relevance of ARF expression seems to decrease in late stages of infection (PL).
Article
Agriculture, Dairy & Animal Science
Jose A. Quinteros, Peter C. Scott, Timothy B. Wilson, Arif M. Anwar, Tyrone Scott, Chithralekha Muralidharan, Thi Thu Hao Van, Robert J. Moore
Summary: The experimental study showed that isoquinoline alkaloids (IQA) provided protection against spotty liver disease (SLD) in chickens by reducing liver lesions, decreasing proinflammatory cytokine release, altering gut microbiota structure, and positively impacting production indicators.
Review
Veterinary Sciences
Anna Giagu, Martina Penati, Sara Traini, Simone Dore, Maria Filippa Addis
Summary: Mastitis is a major disease in dairy farming, and its detection is crucial for effective treatment. Non-enzymatic milk proteins have been investigated as alternative biomarkers for mastitis, and immunoassay techniques have been developed for their detection. However, there is significant heterogeneity among studies, highlighting the need for standardized criteria.
VETERINARY RESEARCH COMMUNICATIONS
(2022)
Article
Biochemistry & Molecular Biology
Ekaterina Mikhailovna Stakhneva, Elena Vladimirovna Kashtanova, Yana Vladimirovna Polonskaya, Eugeniia Vitalievna Striukova, Viktoriya Sergeevna Shramko, Evgeny Viktorovich Sadovski, Alexey Vitalievich Kurguzov, Ivan Sergeevich Murashov, Alexander Mikhailovich Chernyavskii, Yuliya Igorevna Ragino
Summary: Quantitative proteomics studies revealed associations between several blood proteins and the presence of unstable atherosclerotic plaques in the arteries of patients with coronary atherosclerosis, including afamin, attractin, components of the complement system, hemopexin, and haptoglobin. These findings provide insight into the potential roles of these blood proteins in the development of coronary atherosclerosis and their potential as biomarkers for further research.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Veterinary Sciences
Kenji Tsukano, Tatsuya Fukuda, Keiko Ikeda, Kaoru Sato, Kazuyuki Suzuki
Summary: Through a study of 20 Japanese Black cows, it was determined that serum iron concentration can be a satisfactory substitute for inflammatory markers such as haptoglobin and serum amyloid A in cows with respiratory diseases.
JOURNAL OF VETERINARY MEDICAL SCIENCE
(2021)
Review
Agriculture, Dairy & Animal Science
Raiza F. Silveira, Cesar A. Roque-Borda, Eduardo F. Vicente
Summary: Feed additives have been beneficial in animal nutrition, but the use of antibiotics has led to antimicrobial resistance. Antimicrobial peptides are a promising alternative to prevent the development of resistant microorganisms and improve feed efficiency in animal nutrition.
Article
Agriculture, Dairy & Animal Science
Kalai Vaani Muniandy, Eric Lim Teik Chung, Mimi Syazwani Jaapar, Muhammad Hazziq Mohd Hamdan, Mohd Farhan Hanif Reduan, Annas Salleh, Faez Firdaus Abdullah Jesse
Summary: The study aimed to determine the hematological, serum biochemical, and acute phase protein responses in sheep fed with low and high levels of Brachiaria decumbens diets. Significant differences were found in various parameters between different time phases and treatment groups. The results showed variations in hematology, biochemistry, and APPs responses in both serum and cerebrospinal fluid.
TROPICAL ANIMAL HEALTH AND PRODUCTION
(2021)
Article
Agriculture, Dairy & Animal Science
Zoi Prentza, Francesco Castellone, Matteo Legnardi, Birgit Antlinger, Maia Segura-Wang, Giorgos Kefalas, Nikolaos Papaioannou, Ioanna Stylianaki, Vasileios G. G. Papatsiros, Giovanni Franzo, Mattia Cecchinato, Konstantinos Koutoulis
Summary: With the ban on using antibiotics as growth promoters, the poultry sector is exploring alternatives to support production efficiency. Synbiotics, which combine prebiotics and probiotics, show promise in sustaining gut health and improving chicken performance. This study tested the synbiotic PoultryStar((R)) sol on broiler flocks and found that it improved gut health, body weight gain, feed conversion efficiency, and liveability.
Article
Agriculture, Dairy & Animal Science
Georgios Maragkakis, Labrini V. Athanasiou, Serafeim C. Chaintoutis, Dimitra Psalla, Polychronis Kostoulas, Eleftherios Meletis, Georgios Papakonstantinou, Dominiek Maes, Georgios Christodoulopoulos, Vasileios G. Papatsiros
Summary: This study aimed to compare the effects of intradermal and intramuscular administration of a PRRSV-1 MLV vaccine on the health and performance of piglets. The results showed that intradermal vaccination with the PRRSV-1 MLV vaccine had a positive impact on piglets' health and performance, including improved body weight, lower lung and pleurisy lesions scores, and decreased mortality rate.
Editorial Material
Pathology
Seamus Kennedy
JOURNAL OF COMPARATIVE PATHOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Ioannis Nanas, Stella Dokou, Labrini V. Athanasiou, Eleni Dovolou, Thomas M. Chouzouris, Stelios Vasilopoulos, Katerina Grigoriadou, Ilias Giannenas, Georgios S. Amiridis
Summary: This study investigated the effects of partially replacing soybean meal with a mixture of flaxseed and lupins on milk production and fertility parameters in dairy cows during the transition period. The results showed that the dietary treatment had no significant effect on milk yield or composition. However, cows fed with flaxseed and lupin seeds exhibited earlier postpartum estrus and conception compared to the control group. These findings suggest that the substitution of soybean meal with flaxseed and lupin is a profitable feed modification that improves overall fertility in dairy cows.
Article
Biology
Labrini V. Athanasiou, Constantina N. Tsokana, Dimitris A. Gougoulis, Athanasia H. Tzivara, Anna Dedousi, Panagiotis D. Katsoulos
Summary: The occurrence of co-infected hosts and questing ticks with multiple tick-borne pathogens is expected in endemic regions. Limited data exist on the clinicopathological alterations in co-infected sheep. This study investigated the impact of A. phagocytophilum and B. burgdorferi s.l. seropositivity, alone and in combination, on the hematological parameters of naturally infected sheep. Co-exposure to A. phagocytophilum and B. burgdorferi s.l. resulted in the most severe blood abnormalities and enhanced the pathogenic processes. More studies are needed to clarify the possible background mechanisms.
Article
Veterinary Sciences
Georgios I. I. Papakonstantinou, Dimitrios A. A. Gougoulis, Nikolaos Voulgarakis, Georgios Maragkakis, Dimitrios Galamatis, Labrini V. V. Athanasiou, Vasileios G. G. Papatsiros
Summary: This study aimed to evaluate the effects of intramuscular administration of dexamethasone alone or in combination with vitamin E/Se on LBW piglets. The results showed that administering dexamethasone and vitamin E/Se together for 1-3 days after birth can enhance the growth and survival scores of LBW piglets.
VETERINARY SCIENCES
(2023)
Article
Veterinary Sciences
Erasmia D. D. Smyroglou, Labrini V. V. Athanasiou, Rania D. D. Baka, Zoe S. S. Polizopoulou
Summary: The purpose of this study was to compare visual and automated evaluations of dipstick variables in canine urine samples. Automated analysis of urine dipsticks has improved accuracy and precision. However, comparing the two methods, correlation for urine specific gravity was poor and agreement varied for different variables. Visual and automated dipstick urinalyses should not be used interchangeably, and multiple urine samples from the same dog should be evaluated using the same method for accurate results.
VETERINARY SCIENCES
(2023)
Article
Veterinary Sciences
Labrini V. Athanasiou, Constantina N. Tsokana, Dimitrios Doukas, Maria C. Kantere, Panagiotis D. Katsoulos, Georgios I. Papakonstantinou, Eleni G. Katsogiannou, Anna Dedousi
Summary: 13.3% of wild rabbits from Lemnos Island, Greece were infected with E. stiedae, which had negative effects on their liver function.
VETERINARY SCIENCES
(2023)
Article
Veterinary Sciences
Nikolaos Voulgarakis, Dimitrios Gougoulis, Dimitra Psalla, Georgios Papakonstantinou, Panagiotis-Dimitrios Katsoulos, Konstantinos Katsoulis, Mariana Angelidou-Tsifida, Labrini Athanasiou, Vasilleios Papatsiros, Georgios Christodoulopoulos
Summary: Subacute ruminal acidosis (SARA) is a common nutritional disorder in the dairy and beef industries, causing significant financial losses. This study evaluates the effectiveness of computerized rumen colorimetry in detecting SARA in beef cattle. The results show a positive correlation between rumen pH and color components, suggesting computerized rumen colorimetry as a reliable method for managing SARA in bovine farms.
VETERINARY RESEARCH COMMUNICATIONS
(2023)
Article
Food Science & Technology
Vasileios G. Papatsiros, Christos Eliopoulos, Nikolaos Voulgarakis, Dimitrios Arapoglou, Insaf Riahi, Meritxell Sadurni, Georgios I. Papakonstantinou
Summary: This study aimed to investigate the effects of a multi-component mycotoxin-detoxifying agent on pregnant and lactating sows. The results showed that the mycotoxin-detoxifying agent can improve oxidative stress response, as well as the health and performance of sows.
Article
Agriculture, Dairy & Animal Science
Elena I. Pappa, Mariana S. Barbagianni, Stefanos G. Georgiou, Labrini V. Athanasiou, Dimitra Psalla, Dionysios Vekios, Eleni I. Katsarou, Natalia G. C. Vasileiou, Pagona G. Gouletsou, Apostolos D. Galatos, Nikitas N. Prassinos, Dimitris A. Gougoulis, Marianna Angelidou, Vicky Tsioli, George C. Fthenakis, Aikaterini I. Sideri
Summary: This study evaluated the efficacy of using autologous stromal vascular fraction from adipose tissue in enhancing bone healing. The findings suggest that the use of stromal vascular fraction can accelerate post-operative rehabilitation and significantly enhance bone formation, with osteogenic potential comparable to autologous bone graft.
Article
Biochemistry & Molecular Biology
Labrini V. Athanasiou, Eleni G. Katsogiannou, Panagiota Tyrnenopoulou, Dimitrios Gougoulis, Kosmas N. Apostolidis, Stavros M. Papadakis, Kassiopi Christina G. Kokkinaki, Vasileios G. Papatsiros, Constantina N. Tsokana
Summary: This study examined the exposure of horses in Greece to various pathogens and evaluated the diagnostic accuracy of saliva compared to serum. The findings suggest that saliva sampling coupled with IFAT could be successfully used for detecting antibodies against important zoonotic pathogens in horses.
Article
Biology
Georgios I. Papakonstantinou, Dimitra Psalla, Aris Pourlis, Ioanna Stylianaki, Labrini V. Athanasiou, Eleni Tzika, Eleftherios Meletis, Polychronis Kostoulas, George Maragkakis, Georgios Christodoulopoulos, Nikolaos Papaioannou, Vasileios G. Papatsiros
Summary: This study investigated pathological lung lesions in piglets born to gilts vaccinated with PRRSV-1 MLV. The piglets born to gilts vaccinated with the Vac-2 vaccine strain exhibited moderate to severe interstitial pneumonia and type II pneumocyte hyperplasia, while other vaccine groups showed no notable lung lesions.
Article
Veterinary Sciences
Vasileios Georgios Papatsiros, Ioanna Stylianaki, Constantina Nikolaos Tsokana, Georgios Papakonstantinou, Marios Christophorou, Nikolaos Papaioannou, Labrini Vasileios Athanasiou
Summary: This study reported the histopathological lesions caused by an outbreak of acute Actinobacillus pleuropneumoniae serotype 8 infections in two farms in Cyprus for the first time. The macroscopic lesions included fibrotic, hemorrhagic, and necrotizing pneumonia with abscesses and pleuritis. Histopathological evaluation revealed fibrous exudate, areas of necrosis, and degenerated bronchial and bronchiolar epithelia. The A. pleuropneumoniae serotype 8 cases were accompanied by acute illness, death, and pronounced bronchitis and bronchiolitis.
VETERINARY RESEARCH FORUM
(2023)
Article
Veterinary Sciences
Vasileios Papatsiros, Georgios Papakonstantinou, Eleftherios Meletis, Dimitra Bitchava, Polychronis Kostoulas
Summary: The objective of this study was to evaluate the efficacy of a double PCV2 vaccination in weaning piglets reared for gilts under field conditions. The study was conducted at a Greek pig farm with a previous history of PCV2 infections. The results indicated that the double-vaccinated piglets had better growth performance and a stronger humoral response against PCV2 compared to the single-vaccinated piglets. These findings suggest that a double PCV2 vaccination could provide higher protection against the virus for piglets reared on PCV2-affected farms.
VETERINARY RESEARCH FORUM
(2023)
