期刊
ANGIOLOGY
卷 66, 期 3, 页码 278-285出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/0003319714526035
关键词
serum albumin level; no-reflow phenomenon; primary percutaneous coronary intervention; acute myocardial infarction
Low serum albumin (SA) levels are associated with increased cardiovascular mortality. We investigated whether baseline SA levels are associated with no-reflow following primary percutaneous coronary intervention (pPCI). A total of 536 patients (aged 60 +/- 13 years; 74% men) who underwent pPCI were enrolled. The patients were divided into 2 groups: no-reflow and normal-reflow. No-reflow was defined as thrombolysis in myocardial infarction 2 flow. Admission SA levels were significantly lower in the no-reflow group than in the normal-reflow group (3.55 +/- 0.44 vs 4.01 +/- 0.32 mg/dL, P < .001). Also, high-sensitivity C-reactive protein (hsCRP), creatinine, creatine kinase myocardial band isoenzyme, and troponin T were significantly higher while hemoglobin and left ventricular ejection fraction (LVEF) were significantly lower in the no-reflow group. In multivariate analysis, SA level remained an independent predictor of angiographic no-reflow (odds ratio 0.114, 95% confidence interval 0.032-0.405, P = .001) together with LVEF, hsCRP, and baseline culprit artery patency. Admission SA level was an independent predictor of no-reflow after pPCI.
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