Using the Population-Shift Mechanism to Rationally Introduce “Hill-type” Cooperativity into a Normally Non-Cooperative Receptor

Allosterically Tunable, DNA-Based Switches Triggered by Heavy Metals

(2013) Alessandro Porchetta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amplifying Genetic Logic Gates

(2013) J. Bonnet et al.   SCIENCE

Ultrasensitive response motifs: basic amplifiers in molecular signalling networks

(2013) Q. Zhang et al.   Open Biology

Multianalyte Digital Enzyme Biosensors with Built-in Boolean Logic

(2012) Evgeny Katz et al.   ANALYTICAL CHEMISTRY

Decrease in RNA Folding Cooperativity by Deliberate Population of Intermediates in RNA G-Quadruplexes

(2012) Chun Kit Kwok et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rational Design of Allosteric Inhibitors and Activators Using the Population-Shift Model: In Vitro Validation and Application to an Artificial Biosensor

(2012) Francesco Ricci et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Digital Switching of Local Arginine Density in a Genetically Encoded Self-Assembled Polypeptide Nanoparticle Controls Cellular Uptake

(2012) Sarah R. MacEwan et al.   NANO LETTERS

High-fidelity determination of security threats via a Boolean biocatalytic cascade

(2011) Min-Chieh Chuang et al.   CHEMICAL COMMUNICATIONS

Nanoparticles that communicate in vivo to amplify tumour targeting

(2011) Geoffrey von Maltzahn et al.   NATURE MATERIALS

High-Precision, In Vitro Validation of the Sequestration Mechanism for Generating Ultrasensitive Dose-Response Curves in Regulatory Networks

(2011) Francesco Ricci et al.   PLoS Computational Biology

Thermodynamic basis for the optimization of binding-induced biomolecular switches and structure-switching biosensors

(2009) A. Vallee-Belisle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly sensitive “turn-on” fluorescent sensor for Hg2+ in aqueous solution based on structure-switching DNA

(2008) Zidong Wang et al.   CHEMICAL COMMUNICATIONS

E-DNA sensors for convenient, label-free electrochemical detection of hybridization

(2008) Francesco Ricci et al.   MICROCHIMICA ACTA

Cooperativity and biological complexity

(2008) Adrian Whitty   Nature Chemical Biology

Light-activated DNA binding in a designed allosteric protein

(2008) D. Strickland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA