Direct Asymmetric Mannich-Type Reaction of α-Isocyanoacetates with Ketimines using Cinchona Alkaloid/Copper(II) Catalysts

Direct Catalytic Enantio- and Diastereoselective Mannich Reaction of Isocyanoacetates and Ketimines

(2014) Irene Ortín et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Diastereo- and Enantioselective Silver-Catalyzed Double [3+2] Cyclization of α-Imino Esters with Isocyanoacetate

(2014) Pan-Lin Shao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CinchonaAlkaloid-Derived Thiourea-Catalyzed Diastereo- and Enantioselective [3+2] Cycloaddition Reaction of Isocyanoacetates to Isatins: A Facile Access to Optically Active Spirooxindole Oxazolines

(2013) Mei-Xin Zhao et al.   ADVANCED SYNTHESIS & CATALYSIS

Cinchona Alkaloid Amide/Copper(II) Catalyzed Diastereo- and Enantioselective Vinylogous Mannich Reaction of Ketimines with Siloxyfurans

(2013) Masashi Hayashi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hydrogen-Bond-Directed Enantioselective Decarboxylative Mannich Reaction of β-Ketoacids with Ketimines: Application to the Synthesis of Anti-HIV Drug DPC 083

(2013) Hai-Na Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric construction of fluorinated imidazolidines via Cu(i)-catalyzed exo′-selective 1,3-dipolar cycloaddition of azomethine ylides with fluorinated imines

(2013) Qing-Hua Li et al.   CHEMICAL COMMUNICATIONS

Catalytic Enantioselective Allylation of Ketimines by Using Palladium Pincer Complexes with Chiral Bis(imidazoline)s

(2013) Shuichi Nakamura et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cinchona Alkaloid Squaramide Catalyzed Enantioselective Hydrazination/Cyclization Cascade Reaction of α-Isocyanoacetates and Azodicarboxylates: Synthesis of Optically Active 1,2,4-Triazolines

(2013) Mei-Xin Zhao et al.   JOURNAL OF ORGANIC CHEMISTRY

Cyclopropenimine-Catalyzed Enantioselective Mannich Reactions of tert-Butyl Glycinates with N-Boc-Imines

(2013) Jeffrey S. Bandar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Chiral Bis(betaine) Catalyst for the Mannich Reaction of Azlactones and Aliphatic Imines

(2012) Wen-Quan Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic stereocontrolled synthesis of 3,3′-pyrrolidinyl spirooxindoles by [3+2] annulation of isocyanoesters with methyleneindolinones

(2012) Liang-Liang Wang et al.   CHEMICAL COMMUNICATIONS

Catalytic asymmetric Mannich reaction of glycine Schiff bases with α-amido sulfones as precursors of aliphatic imines

(2012) Elier Hernando et al.   CHEMICAL COMMUNICATIONS

syn-Selective Asymmetric Mannich Reaction of Sulfonyl Imines with Iminoesters Catalyzed by the N,N,N-Tridentate Bis(imidazolidine)pyridine (PyBidine)-Cu(OTf)2 Complex

(2012) Takayoshi Arai et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Synthesis of AG-041R by using N-Heteroarenesulfonyl Cinchona Alkaloid Amides as Organocatalysts

(2012) Noriyuki Hara et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Formal [3+2] Cycloaddition Reaction of α-Aryl Isocyanoesters withN-Aryl Maleimides by Bifunctional Cinchona Alkaloids-Based Squaramide/AgSbF6Cooperative Catalysis

(2012) Mei-Xin Zhao et al.   Chemistry-An Asian Journal

Recent Advances in Asymmetric Isocyanide-Based Multicomponent Reactions

(2012) Sander S. van Berkel et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Proline-Catalyzed Addition of Aldehydes to 3H-Indol-3-ones: Enantioselective Synthesis of 2,3-Dihydro-1H-indol-3-ones with Quaternary Stereogenic Centers

(2012) Magnus Rueping et al.   HELVETICA CHIMICA ACTA

Asymmetric Michael Addition of α-Substituted Isocyanoacetates with Maleimides Catalyzed by Chiral Tertiary Amine Thiourea

(2012) Jian-Fei Bai et al.   JOURNAL OF ORGANIC CHEMISTRY

Au-Catalyzed Asymmetric Formal [3 + 2] Cycloaddition of Isocyanoacetates with Maleimides

(2012) Silvia Padilla et al.   JOURNAL OF ORGANIC CHEMISTRY

Cinchona Alkaloid Amides/Dialkylzinc Catalyzed Enantioselective Desymmetrization of Aziridines with Phosphites

(2012) Masashi Hayashi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic Chiral Ion Pair Catalysts for Asymmetric Catalytic Synthesis of Quaternary α,β-Diamino Acids

(2012) Shi-Hui Shi et al.   ORGANIC LETTERS

Enantioselective Synthesis of Imidazolines with Quaternary Stereocenters by Organocatalytic Reaction of N-(Heteroarenesulfonyl)imines with Isocyanoacetates

(2012) Shuichi Nakamura et al.   ORGANIC LETTERS

Synthesis of N-Alkoxycarbonyl Ketimines Derived from Isatins and Their Application in Enantioselective Synthesis of 3-Aminooxindoles

(2012) Wenjin Yan et al.   ORGANIC LETTERS

Chiral Copper Amide Catalyzed Asymmetric Mannich-Type Reactions of Glycine Schiff Bases

(2012) Yasuhiro Yamashita et al.   Asian Journal of Organic Chemistry

Stereodivergent Direct Catalytic Asymmetric Mannich-Type Reactions of α-Isothiocyanato Ester with Ketimines

(2011) Gang Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Diastereo- and Enantioselective Mannich Reactions of Synthetically Flexible Ketimines with Secondary Amine Organocatalysts

(2011) Taichi Kano et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Update 1 of: α,β-Diamino Acids: Biological Significance and Synthetic Approaches

(2011) Alma Viso et al.   CHEMICAL REVIEWS

Asymmetric Formal [3+2] Cycloaddition Reaction of Isocyanoesters to 2-Oxobutenoate Esters by a Multifunctional Chiral Silver Catalyst

(2011) Jin Song et al.   CHEMISTRY-A EUROPEAN JOURNAL

Oxazolones in Organocatalysis, New Tricks for an Old Reagent

(2011) Andrea-Nekane R. Alba et al.   Chemistry-An Asian Journal

Cooperative Catalysis for the First Asymmetric Formal [3+2] Cycloaddition Reaction of Isocyanoacetates to α,β-Unsaturated Ketones

(2011) Carlos Arróniz et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Ag/ThioClickFerrophos-Catalyzed Enantioselective Mannich Reaction and Amination of Glycine Schiff Base

(2011) Kazumi Imae et al.   JOURNAL OF ORGANIC CHEMISTRY

A Dual-Catalysis Approach to the Asymmetric Steglich Rearrangement and Catalytic Enantioselective Addition ofO-Acylated Azlactones to Isoquinolines

(2011) Chandra Kanta De et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gold(I)-Catalyzed Diastereo- and Enantioselective 1,3-Dipolar Cycloaddition and Mannich Reactions of Azlactones

(2011) Asa D. Melhado et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A New Family of Cinchona-Derived Amino Phosphine Precatalysts: Application to the Highly Enantio- and Diastereoselective Silver-Catalyzed Isocyanoacetate Aldol Reaction

(2011) Filippo Sladojevich et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Diastereo- and Enantioselective Aldol Reaction of Methyl α-Isocyanoacetate: A Cooperative Catalysis Approach

(2011) Hun Young Kim et al.   ORGANIC LETTERS

N-(Heteroarenesulfonyl)prolinamides-Catalyzed Aldol Reaction between Acetone and Aryl Trihalomethyl Ketones

(2011) Noriyuki Hara et al.   ORGANIC LETTERS

Catalytic Asymmetric Mannich Reaction of Glycine Derivatives with N-Tosylimines using Copper(I)/TF-BiphamPhos Complex

(2010) Gang Liang et al.   ADVANCED SYNTHESIS & CATALYSIS

Robust Generation of Lead Compounds for Protein-Protein Interactions by Computational and MCR Chemistry: p53/Hdm2 Antagonists

(2010) Anna Czarna et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Isocyanoacetate Derivatives: Synthesis, Reactivity, and Application

(2010) Anton V. Gulevich et al.   CHEMICAL REVIEWS

Diastereoselective Silver-Catalyzed 1,3-Dipolar Cycloaddition of Azomethine Ylides with Fluorinated Imine

(2010) Haibo Xie et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Syntheses Using Heteroarenesulfonyl Groups as a Highly Functional Protecting-activating Group

(2010) Shuichi Nakamura et al.   JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN

Chiral Brønsted Acid Catalyzed Enantioselective Addition of α-Isocyanoacetamides to Aldehydes

(2010) Xiaofei Zeng et al.   ORGANIC LETTERS

Highly Enantio- and Diastereoselective Mannich Reactions of Glycine Schiff Bases within situGeneratedN-Boc-imines Catalyzed by a Cinchona Alkaloid Thiourea

(2010) Haile Zhang et al.   ORGANIC LETTERS

Asymmetric Aza-Mannich Addition of Oxazolones toN-Tosyl Aldimines: Synthesis of Chiral α-Disubstituted α,β-Diamino Acids

(2010) Xiaodong Liu et al.   ORGANIC LETTERS

Synthesis of 1,2,4-Triazolines: Base-Catalyzed Hydrazination/Cyclization Cascade of α-Isocyano Esters and Amides

(2010) David Monge et al.   ORGANIC LETTERS

Organocatalytic asymmetric Mannich-type reaction of N-sulfonylimines with isocyanoacetate leading to optically active 2-imidazoline-4-carboxylates

(2010) Zhen-Wei Zhang et al.   TETRAHEDRON-ASYMMETRY

Organocatalytic Asymmetric Synthesis of Protected α,β-Diamino Acids

(2009) Zugui Shi et al.   ADVANCED SYNTHESIS & CATALYSIS

Recent Advances in the Synthesis of 2-Imidazolines and Their Applications in Homogeneous Catalysis

(2009) Han Liu et al.   ADVANCED SYNTHESIS & CATALYSIS

Brønsted Acid Catalyzed Enantioselective Three-Component Reaction Involving the α Addition of Isocyanides to Imines

(2009) Tao Yue et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Flexible synthesis, structural determination, and synthetic application of a new C1-symmetric chiral ammonium betaine

(2009) Daisuke Uraguchi et al.   CHEMICAL COMMUNICATIONS

Catalytic asymmetric direct Mannich reaction: a powerful tool for the synthesis of α,β-diamino acids

(2009) Ramón Gómez Arrayás et al.   CHEMICAL SOCIETY REVIEWS

AN,N′-Dioxide-Copper(II) Complex as an Efficient Catalyst for the Enantioselective and Diastereoselective Mannich-Type Reaction of Glycine Schiff Bases with Aldimines

(2009) Deju Shang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Substrate-Controlled Diastereoselectivity Switch in Catalytic Asymmetric Direct Mannich Reaction of Glycine Derivatives with Imines: Fromanti- tosyn-α,β-Diamino Acids

(2009) Jorge Hernández-Toribio et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Enantioselective Aza-Henry Reactions

(2009) Eugenia Marqués-López et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Catalytic Asymmetric Passerini-Type Reaction: Chiral Aluminum−Organophosphate-Catalyzed Enantioselective α-Addition of Isocyanides to Aldehydes

(2009) Tao Yue et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Enantioselective Hydrophosphonylation of Ketimines Using Cinchona Alkaloids

(2009) Shuichi Nakamura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective Synthesis of α,β-Diamino Acid Derivatives

(2009) Le Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Heterobimetallic Ga/Yb-Schiff Base Complex for Catalytic Asymmetric α-Addition of Isocyanides to Aldehydes

(2009) Hisashi Mihara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective catalytic addition of nitroesters to N-carboalkyloxy imines: a route to quaternary stereocenters

(2009) Alessandra Puglisi et al.   TETRAHEDRON LETTERS

Highly Enantioselective Construction of a Quaternary Carbon Center of Dihydroquinazoline by Asymmetric Mannich Reaction and Chiral Recognition

(2008) Biao Jiang et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic Asymmetric Formal [3+2] Cycloaddition Reaction of Isocyanoesters to Nitroolefins Leading to Highly Optically Active Dihydropyrroles

(2008) Chang Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of 5-(1-Hydroxyalkyl)tetrazoles by Catalytic Enantioselective Passerini-Type Reactions

(2008) Tao Yue et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly enantioselective organocatalytic formation of a quaternary carbon center via chiral Brønsted acid catalyzed self-coupling of enamides

(2008) Christine Baudequin et al.   CHEMICAL COMMUNICATIONS

Asymmetric Reductive Mannich Reaction to Ketimines Catalyzed by a Cu(I) Complex

(2008) Yao Du et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis, Structure, and Catalytic Performance of Diastereopure Five-Coordinated NCN-Pincer Palladium(II) Complexes Bearing Bulky Amino Acid Substituents

(2008) Silvia Gosiewska et al.   ORGANOMETALLICS

Chiral palladium-pincer complex catalyzed asymmetric condensation of sulfonimines and isocyanoacetate

(2008) Juhanes Aydin et al.   TETRAHEDRON-ASYMMETRY

Convenient enantioselective synthesis of β-trifluoromethyl-β-aminoketones by organocatalytic asymmetric Mannich reaction of aryl trifluoromethyl ketimines with acetone

(2008) Volodymyr A. Sukach et al.   TETRAHEDRON-ASYMMETRY

Catalytic Enantioselective Passerini Three-Component Reaction

(2007) Shi-Xin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Tertiary Diamines in Asymmetric Synthesis

(2007) Jean-Claude Kizirian   CHEMICAL REVIEWS

Enantioselective CC Bond Formation to Sulfonylimines through Use of the 2-Pyridinesulfonyl Group as a Novel Stereocontroller

(2007) Shuichi Nakamura et al.   CHEMISTRY-A EUROPEAN JOURNAL