A Comparative CEST NMR Study of Slow Conformational Dynamics of Small GTPases Complexed with GTP and GTP Analogues

Membrane-Dependent Modulation of the mTOR Activator Rheb: NMR Observations of a GTPase Tethered to a Lipid-Bilayer Nanodisc

(2013) Mohammad T. Mazhab-Jafari et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NMR-based functional profiling of RASopathies and oncogenic RAS mutations

(2013) M. J. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metal-Bis(2-picolyl)amine Complexes as State 1(T) Inhibitors of Activated Ras Protein

(2012) Ina C. Rosnizeck et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Studying “Invisible” Excited Protein States in Slow Exchange with a Major State Conformation

(2012) Pramodh Vallurupalli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Solution Structure of the State 1 Conformer of GTP-bound H-Ras Protein and Distinct Dynamic Properties between the State 1 and State 2 Conformers

(2011) Mitsugu Araki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cu2+-cyclen as Probe to Identify Conformational States in Guanine Nucleotide Binding Proteins

(2011) Tanja Meierhofer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Atomic-resolution dynamics on the surface of amyloid-β protofibrils probed by solution NMR

(2011) Nicolas L. Fawzi et al.   NATURE

Stabilizing a Weak Binding State for Effectors in the Human Ras Protein by Cyclen Complexes

(2010) Ina C. Rosnizeck et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural Basis for Conformational Dynamics of GTP-bound Ras Protein

(2010) Fumi Shima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational States of Human Rat Sarcoma (Ras) Protein Complexed with Its Natural Ligand GTP and Their Role for Effector Interaction and GTP Hydrolysis

(2010) Michael Spoerner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Real-time NMR Study of Three Small GTPases Reveals That Fluorescent 2′(3′)-O-(N-Methylanthraniloyl)-tagged Nucleotides Alter Hydrolysis and Exchange Kinetics

(2009) Mohammad T. Mazhab-Jafari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fundamental Link between Folding States and Functional States of Proteins

(2009) Hans Robert Kalbitzer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Characterization of the Intrinsic and TSC2-GAP-Regulated GTPase Activity of Rheb by Real-Time NMR

(2009) C. B. Marshall et al.   Science Signaling

Two conformational states of Ras GTPase exhibit differential GTP-binding kinetics

(2008) Jingling Liao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Global Conformational Dynamics in Ras†

(2008) Casey O’Connor et al.   BIOCHEMISTRY