Platinum(IV) Prodrugs with Haloacetato Ligands in the Axial Positions can Undergo Hydrolysis under Biologically Relevant Conditions

Combating the Drug Resistance of Cisplatin Using a Platinum Prodrug Based Delivery System

(2012) Yuanzeng Min et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dependence of the Reduction Products of Platinum(IV) Prodrugs upon the Configuration of the Substrate, Bulk of the Carrier Ligands, and Nature of the Reducing Agent

(2012) Marilù Sinisi et al.   INORGANIC CHEMISTRY

Cellular interactions of platinum drugs

(2012) Ezequiel Wexselblatt et al.   INORGANICA CHIMICA ACTA

What do we know about the reduction of Pt(IV) pro-drugs?

(2012) Ezequiel Wexselblatt et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Pt(iv) analogs of oxaliplatin that do not follow the expected correlation between electrochemical reduction potential and rate of reduction by ascorbate

(2011) Jenny Z. Zhang et al.   CHEMICAL COMMUNICATIONS

Anticancer Platinum (IV) Prodrugs with Novel Modes of Activity

(2011) Chee Fei Chin et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

New reduction pathways for ctc-[PtCl2(CH3CO2)2(NH3)(Am)] anticancer prodrugs

(2010) Alina Nemirovski et al.   CHEMICAL COMMUNICATIONS

The status of platinum anticancer drugs in the clinic and in clinical trials

(2010) Nial J. Wheate et al.   DALTON TRANSACTIONS

Molecular and statistical modeling of reduction peak potential and lipophilicity of platinum(IV) complexes

(2010) James A. Platts et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Tuning of lipophilicity and cytotoxic potency by structural variation of anticancer platinum(IV) complexes

(2010) Michael R. Reithofer et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate

(2009) Shanta Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer

(2008) E D Michelakis et al.   BRITISH JOURNAL OF CANCER

[1H,15N] Heteronuclear Single Quantum Coherence NMR Study of the Mechanism of Aquation of Platinum(IV) Ammine Complexes

(2008) Murray S. Davies et al.   INORGANIC CHEMISTRY

Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles

(2008) S. Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA