Glycomics for Drug Discovery: Metabolic Perturbation in Androgen-Independent Prostate Cancer Cells Induced by Unnatural Hexosamine Mimics

Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells

(2011) Tracey M Gloster et al.   Nature Chemical Biology

An Efficient Approach to the Discovery of Potent Inhibitors against Glycosyltransferases

(2010) Kensaku Hosoguchi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structural and mechanistic basis for a new mode of glycosyltransferase inhibition

(2010) Thomas Pesnot et al.   Nature Chemical Biology

Chemical Approaches To Perturb, Profile, and Perceive Glycans

(2009) Nicholas J. Agard et al.   ACCOUNTS OF CHEMICAL RESEARCH

Fluorinated per-acetylated GalNAc metabolically alters glycan structures on leukocyte PSGL-1 and reduces cell binding to selectins

(2009) D. D. Marathe et al.   BLOOD

Metabolism, Cell Surface Organization, and Disease

(2009) James W. Dennis et al.   CELL

Threshold in Stage-specific Embryonic Glycotypes Uncovered by a Full Portrait of DynamicN-Glycan Expression during Cell Differentiation

(2009) Maho Amano et al.   MOLECULAR & CELLULAR PROTEOMICS