Article
Chemistry, Multidisciplinary
Christopher S. Gravatt, Luis Melecio-Zambrano, Tehshik P. Yoon
Summary: The sole method available for the photocycloaddition of unconjugated aliphatic alkenes is the Cu-catalyzed Salomon-Kochi reaction. A new catalyst system with superior reactivity and photostability has been designed, offering significantly expanded substrate scope and highlighted through the preparation of the natural products sulcatine G and perforatol.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Review
Chemistry, Physical
Jaehan Bae, Eun Jin Cho
Summary: Bidentate P,N ligands, integrating phosphine and nitrogen donors, have versatile characteristics and offer electronic and steric tunability. This Review focuses on Ni-catalyzed cross-coupling reactions mediated by P,N ligands, with their asymmetrical nature playing a crucial role in the catalytic cycle and providing control, stability, and unique regioselectivity in catalytic processes.
Article
Chemistry, Medicinal
Mahboubeh Hosseini-Kharat, Rahmatollah Rahimi, Ali Mohammad Alizadeh, Davit Zargarian, Solmaz Khalighfard, Loic P. Mangin, Nasim Mahigir, Seyed Hasan Ayati, Amir Abbas Momtazi-Borojeni
Summary: Triple-negative breast cancer (TNBC) is a highly aggressive form of breast cancer with high metastasis rates due to multidrug resistance. While platinum-based antitumor agents have severe side effects, nickel and palladium complexes are being investigated as potentially safer alternatives. Among these, palladium derivatives have been found to be safer and effective inhibitors of TNBC cell adhesion and migration.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
(2021)
Article
Chemistry, Multidisciplinary
James P. Durrant, Benjamin M. Day, Jinkui Tang, Akseli Mansikkamaki, Richard A. Layfield
Summary: Replacing the ligands in dysprosium single-molecule magnets with a different type leads to larger energy barriers to magnetization reversal. The distances between the ligands in the new complexes suggest a different crystal field splitting. Theoretical analysis shows that the magnetic axes in the ground Kramers doublets are oriented towards the new ligands. Introducing new parameters allows for comparisons between different single-molecule magnets, indicating the potential for improved performance in the new system.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Organic
R. Rengasamy, J. Paul Raj, K. Vijayalakshmi, N. Punitha, M. Kesavan, M. Vajjiravel, Jebamalai Elangovan
Summary: A tunable synthesis of 1,4,5-trisubstituted 1,2,3-triazoles and enamines through [3+2] cycloaddition of activated olefins and organic azides is reported. Triazoles were obtained from benzylidene diketones and organic azides using copper oxide nanoparticle catalysis, while enamines were synthesized from benzylidene malonates and organic azides under solvent-free and catalyst-free conditions.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
C. Vance Thompson, Hadi D. Arman, Zachary J. Tonzetich
Summary: This study reveals different reaction pathways of iron catalysts in the hydrosilylation of aldehydes and ketones, depending on the precatalyst and substrate selection.
Article
Chemistry, Physical
Chance M. Boudreaux, Dinesh Nugegoda, Wenzhi Yao, Nghia Le, Nathan C. Frey, Qing Li, Fengrui Qu, Matthias Zeller, Charles Edwin Webster, Jared H. Delcamp, Elizabeth T. Papish
Summary: Low-valent cobalt complexes with phosphine substitution have been synthesized and shown to be highly active catalysts for photocatalytic CO2 reduction.
Article
Chemistry, Physical
Dongshun Ni, M. Kevin Brown
Summary: A Ni-catalyzed silylacylation of alkenes is introduced, providing rapid access to beta-silyl ketones by combining alkenes, CIZnSiR3, and acid chlorides. The method involves a catalytic intermediate of [Ni]-SiR3 complex, which is rare for three-component alkene functionalization. The synthetic utility of the products is demonstrated, along with detailed mechanistic descriptions.
Article
Chemistry, Multidisciplinary
Dongyang Wang, Yuhang Lai, Peng Wang, Xuebing Leng, Jie Xiao, Liang Deng
Summary: The selective Markovnikov hydrosilylation reactions of terminal alkynes with tertiary silanes using a dicobalt carbonyl N-heterocyclic carbene (NHC) complex as catalyst presented in this study, provide an efficient method for synthesizing alpha-vinylsilanes with good functional group compatibility and high alpha/beta selectivity. Mechanistic study revealed the formation of dinuclear cobalt alkyne and mononuclear cobalt silyl complexes during the reactions, with the mono(NHC) dicobalt complex exhibiting higher catalytic activity over di(NHC)-dicobalt complexes.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Applied
Jiaqing Xu, Wangyu Shi, Min Liu, Jianning Liao, Wei Wang, Yongjun Wu, Hongchao Guo
Summary: A palladium-catalyzed [4+2] cycloaddition reaction has been developed for the efficient synthesis of tetrahydropyran derivatives with good selectivity.
ADVANCED SYNTHESIS & CATALYSIS
(2022)
Article
Chemistry, Multidisciplinary
Yunlong Zhao, Chen-Fei Liu, Leroy Qi Hao Lin, Albert S. C. Chan, Ming Joo Koh
Summary: In this study, a N-heterocyclic carbene-Ni-I catalytic species was used to achieve highly substituted alkenes from abundant monosubstituted substrates with excellent regio- and stereoselectivities. Trimethylsilyl triflate and trimethylamine additives were added to mediate the reaction, resulting in the generation of trisubstituted boron- and arene-containing trans alkenes. This method represents a significant addition to the toolbox of reactions for the concise synthesis of unsaturated biologically active compounds.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Durga Prasad Hari, Guillaume Pisella, Matthew D. Wodrich, Artem Tsymbal, Farzaneh Fadaei Tirani, Rosario Scopelliti, Jerome Waser
Summary: A new oxyalkynylation/cycloaddition reaction has been reported to synthesize complex polycyclic structures under mild conditions, with high efficiency and atom economy. The obtained products can be applied as chiral ligands for metal catalysis, providing a new method for organic synthesis. Computational studies provided a first rationalization of the low activation energy for the cycloaddition reaction based on counter-intuitive favorable dispersive interactions in the transition state.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Applied
Yu Liu, Jiayun Li, Ying Bai, Jiajian Peng
Summary: A series of nitrogen phosphine ligands were synthesized for investigating the hydrosilylation reaction of alkenes catalyzed using MCl2. Among them, the CoCl2/N,P-ligand catalyst system showed high catalytic activity and excellent selectivity, achieving close to 100% selectivity for beta-adduct.
APPLIED ORGANOMETALLIC CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Konstantin N. Gavrilov, Ilya V. Chuchelkin, Vladislav K. Gavrilov, Sergey V. Zheglov, Ilya D. Firsin, Valeria M. Trunina, Nataliya E. Borisova, Yan P. Bityak, Olga A. Maloshitskaya, Victor A. Tafeenko, Vladislav S. Zimarev, Nataliya S. Goulioukina
Summary: A series of diamidophosphite-sulfides with diverse structures were synthesized from 1,2-thioether alcohols. These hemilabile ligands showed the ability to form both P,S-chelates and complexes with two ligands connected to the metal P-monodentately when binding with Pd(II). Their structures were confirmed by 2D NMR spectroscopy and single-crystal X-ray diffraction. The ligands exhibited high asymmetric induction in Pd-catalyzed asymmetric allylic substitutions and allylic alkylations.
Article
Chemistry, Physical
Biao Wang, Tianze Zhang, Li-Jun Xiao, Qi-Lin Zhou
Summary: The addition of MeOLi promotes the ring opening of the aza-nickelacycle intermediate and facilitates hydride transfer from the methoxy group to nickel, enabling the reductive coupling of alkenes with imines. This pathway involving the reductive transformation of saturated aza-nickelcycles allows for highly selective C-C bond formation.
Article
Chemistry, Inorganic & Nuclear
Michael Brady, Sebastian D. Piombo, Chunhua Hu, Daniela Buccella
DALTON TRANSACTIONS
(2016)
Article
Chemistry, Multidisciplinary
Jessica J. Gruskos, Guangqian Zhang, Daniela Buccella
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2016)
Article
Chemistry, Physical
Guangqian Zhang, Denis Jacquemin, Daniela Buccella
JOURNAL OF PHYSICAL CHEMISTRY B
(2017)
Article
Biochemistry & Molecular Biology
Debra R. Rooker, Yuliya Klyubka, Ritika Gautam, Elisa Tomat, Daniela Buccella
Article
Materials Science, Biomaterials
Qitian Lin, Daniela Buccella
JOURNAL OF MATERIALS CHEMISTRY B
(2018)
Article
Chemistry, Physical
William P. Carbery, Brismar Pinto-Pacheco, Daniela Buccella, Daniel B. Turner
JOURNAL OF PHYSICAL CHEMISTRY A
(2019)
Editorial Material
Chemistry, Inorganic & Nuclear
Daniela Buccella, Mi Hee Lim, Janet R. Morrow
INORGANIC CHEMISTRY
(2019)
Review
Biochemistry & Molecular Biology
Tomas S. Lazarou, Daniela Buccella
CURRENT OPINION IN CHEMICAL BIOLOGY
(2020)
Article
Chemistry, Multidisciplinary
Brismar Pinto-Pacheco, William P. Carbery, Sameer Khan, Daniel B. Turner, Daniela Buccella
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2020)
Article
Chemistry, Inorganic & Nuclear
Kirill Miachin, Virginia Del Solar, Elsy El Khoury, Nazia Nayeem, Anton Khrystenko, Patricia Appelt, Michelle C. Neary, Daniela Buccella, Maria Contel
Summary: The potential of ruthenium(II) compounds as an alternative to platinum-based clinical anticancer agents has been unveiled. Studies have shown that ruthenium compounds can be highly effective in treating cisplatin-resistant cell lines, including triple-negative breast cancer. Research indicates that certain ruthenium compounds with fluorophores have a preferential accumulation in the endoplasmic reticulum, mitochondria, and lysosomes.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Physical
William A. Howard, Kraig A. Wheeler, Daniela Buccella
JOURNAL OF MOLECULAR STRUCTURE
(2020)
Meeting Abstract
Chemistry, Multidisciplinary
Brismar Pinto-Pacheco, Daniela Buccella, Sameer Khan, William Carbery, Daniel Turner
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2018)
Meeting Abstract
Chemistry, Multidisciplinary
Debra Rooker, Daniela Buccella
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2016)
Meeting Abstract
Chemistry, Multidisciplinary
Qitian Lin, Daniela Buccella
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2016)
Meeting Abstract
Chemistry, Multidisciplinary
Jessica Gruskos, Guangqian Zhang, Daniela Buccella
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2016)
