Article
Clinical Neurology
Jia Liu, Kun Liu, Huixian Wang, Hongli Hu, Guolin Sun, Xiaofei Ye, Zheng Lou, Jinjun Bian, Lulong Bo
Summary: This study aims to investigate the effectiveness and safety of intravenous lidocaine in patients undergoing ileostomy closure. The time of first postoperative anal venting, postoperative opioids use, postoperative recovery, intraoperative adverse effects, and postoperative complications will be collected and analyzed.
JOURNAL OF PAIN RESEARCH
(2022)
Review
Oncology
Jia Li, Jiao Huang, Jiang-tao Yang, Jing-chen Liu
Summary: This meta-analysis aimed to evaluate the effectiveness of perioperative intravenous lidocaine in relieving postoperative pain among patients undergoing breast surgery. The study found that perioperative intravenous lidocaine significantly reduced the incidence of chronic post-surgical pain and also decreased opioid consumption and length of hospital stay.
FRONTIERS IN ONCOLOGY
(2023)
Review
Medicine, General & Internal
Ingrid Wing-Sum Lee, Stefan Schraag
Summary: This narrative review provides an update on the applied pharmacology of lidocaine, its clinical scope in anaesthesia, novel concepts of analgesic and immune-modulatory effects as well as the current controversy around its use in perioperative opioid-sparing multi-modal strategies.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Chemistry, Medicinal
Jing Sun, Shan Wang, Jun Wang, Xiuxiu Gao, Guanglei Wang
Summary: This study aimed to compare the effect of intravenous infusion of lidocaine with ultrasound-guided transverse abdominal plane (TAP) block on postoperative recovery and analgesia in patients undergoing bariatric surgery. The results showed that both lidocaine infusion and TAP block provided good postoperative recovery and analgesia, but lidocaine infusion had better analgesic effect at 12 hours and 24 hours postoperatively compared with TAP block.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2022)
Article
Clinical Neurology
Yan Xu, Mao Ye, Ying Hong, Yi Kang, Yue Li, Xiao Xiao, Li Zhou, Chunling Jiang
Summary: This prospective trial aims to investigate the efficacy of intraoperative and 72 postoperative hours intravenous lidocaine on postoperative pain and recovery after hepatectomy, providing a new strategy for perioperative pain management for hepatectomy.
JOURNAL OF PAIN RESEARCH
(2021)
Article
Anesthesiology
Seon Ju Kim, Yong Seon Choi, Yong Min Chun, Hye Jin Kim, Chunggu Han, Seokyung Shin
Summary: Intravenous lidocaine may be helpful in reducing opioid requirements during the acute postoperative period in patients undergoing arthroscopic rotator cuff repair. It may be a viable option for multimodal analgesia in ARCR when regional analgesia is not possible.
CLINICAL JOURNAL OF PAIN
(2022)
Article
Surgery
Alp Eren Celenlioglu, Ender Sir, Nadide Ors-Yildirim, Alperen Kutay Yildirim, Mehmet Emin Ince, Suat Doganci
Summary: The aim of this study was to evaluate the effect of perioperative intravenous magnesium sulfate on low back pain severity after iliac venous stent implantation. The results showed that perioperative IV magnesium sulfate infusion was effective in reducing LBP severity, opioid consumption, and the need for additional analgesics in the acute postoperative period. This indicates that perioperative intravenous magnesium sulfate is a safe and effective treatment option.
JOURNAL OF VASCULAR SURGERY-VENOUS AND LYMPHATIC DISORDERS
(2023)
Article
Anesthesiology
Kubra Kutay Yazici, Mensure Kaya, Busra Aksu, Suheyla Unver
Summary: This study investigated the effects of perioperative systemic lidocaine infusion on pain control after major gynecologic oncology surgery. Results showed that lidocaine infusion was as effective as epidural analgesia, with better outcomes in terms of time to first flatus and nausea-vomiting incidence.
CLINICAL JOURNAL OF PAIN
(2021)
Article
Anesthesiology
Chang-Hoon Koo, Junkyu Kim, Hyo-Seok Na, Jung-Hee Ryu, Hyun-Jung Shin
Summary: Lidocaine patch has been shown to reduce postoperative pain without side effects, although its ability to save morphine remains uncertain.
JOURNAL OF CLINICAL ANESTHESIA
(2022)
Article
Chemistry, Medicinal
Xiaofen Li, Jimin Wu, Haiyan Lan, Weifeng Shan, Qiaomin Xu, Xiaoli Dong, Gongchen Duan
Summary: This study found that intraoperative intravenous lidocaine can reduce the incidence of postoperative delirium in elderly patients with hip fracture, without increasing the risk of local anesthetic toxicity.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2023)
Article
Anesthesiology
Martina Rekatsina, Polyxeni Theodosopoulou, Chryssoula Staikou
Summary: The study found that lidocaine significantly reduces postoperative opioid consumption, while dexmedetomidine prevents early postoperative nausea. However, both agents were associated with hypotension and the need for vasopressors. There were no significant differences observed among the groups in terms of other recovery characteristics.
Article
Anesthesiology
Kuo-Chuan Hung, Chin-Chen Chu, Chung-Hsi Hsing, Yang-Pei Chang, Yu-Yu Li, Wei-Cheng Liu, I-Wen Chen, Jen-Yin Chen, Cheuk-Kwan Sun
Summary: Meta-analysis of 14 randomized controlled trials showed that perioperative intravenous lidocaine significantly improved postoperative quality of recovery and reduced intraoperative remifentanil consumption, without increasing the risk of chronic postsurgical pain in patients undergoing elective surgery.
JOURNAL OF CLINICAL ANESTHESIA
(2021)
Article
Surgery
Qingfeng Wei, Ming Xia, Qin Zhang, Zhiping Wang
Summary: The study found that continuous intravenous pumping of lidocaine during the perioperative period has little effect on immune function in breast cancer patients and promotes postoperative recovery.
Article
Anesthesiology
Yan Xu, Mao Ye, Fei Liu, Ying Hong, Yi Kang, Yue Li, Huan Li, Xiao Xiao, Feng Yu, Mengmeng Zhou, Li Zhou, Chunling Jiang
Summary: This study investigated the effect of prolonged intravenous lidocaine infusion on postoperative pain in patients undergoing hepatectomy. The results showed that prolonged lidocaine infusion reduced the incidence of moderate-to-severe movement-evoked pain and postoperative pulmonary complications, and decreased pain scores and opioid consumption.
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Article
Anesthesiology
Hao Guo, Tingting Ao, Jiagao Wang, Xi Zhang, Junwei Zheng, Yun Xiao, Rui Xue, Prakash Kalika, Ran Ran
Summary: Perioperative dexmedetomidine combined with lidocaine infusion can effectively relieve postoperative pain and improve recovery in patients undergoing thyroidectomy.
CLINICAL JOURNAL OF PAIN
(2022)