Article
Toxicology
Ashraf Mahmoud Emara, Khaled Ali Alrasheedi, Salha Dihim Alrashidi, Rehab Mohamed Elgharabawy
Summary: The research aimed to evaluate the effects of long-term exposure to waste anesthetic gases on the immune system of medical theater personnel. The results showed significant changes in immune parameters among the exposed groups, suggesting variations in immunomodulatory responses to WAG exposure among hospital personnel.
JOURNAL OF IMMUNOTOXICOLOGY
(2021)
Article
Veterinary Sciences
Hangbin Chen, Huan Yang, Mengqing Li, Haojie Peng, Weibin Guo, Meng Li
Summary: The objective of this study was to determine if oral gabapentin decreases the minimum alveolar concentration (MAC) of isoflurane in cats. The results showed that gabapentin significantly reduced the MAC of isoflurane in cats without affecting cardiovascular and other vital variables.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Veterinary Sciences
Mohamed Marzok, Adel I. Almubarak, Mahmoud Kandeel, Wael El-Deeb, Hussein Babiker, Sayed Fathi El-Hawari
Summary: This study examined the sparing effect of BUT-LID and TRM-LID on sevoflurane's MAC in dogs. The BUT-LID treatment showed significant MAC reduction while the TRM-LID treatment did not. Both treatments had minimal effects on the cardiorespiratory system.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
Julio Raul Chavez-Monteagudo, Jose Antonio Ibancovichi, Pedro Sanchez-Aparicio, Sergio Recillas-Morales, Jorge Osorio-Avalos, Marco Antonio De Paz-Campos
Summary: The minimum alveolar concentration of isoflurane was determined in male rats treated with WIN 55,212-2, showing an increase in minimum alveolar concentration after chronic use. This effect persisted even after discontinuation of the synthetic cannabinoid for 8 days.
Article
Multidisciplinary Sciences
Zheng Xie, Robert Fong, Aaron P. Fox
Summary: This study confirms that combining a low dose of propofol or sevoflurane with Dex can create an effective anesthesia, which can be rapidly reversed by atipamezole and caffeine.
Article
Anesthesiology
Patrick R. Kolbay, Joseph A. Orr, Kai Kuck
Summary: Fusion of flow sensors can be used for monitoring volatile anesthetic concentrations as a low-cost, low-maintenance alternative to infrared spectroscopy. Ultrasonic and orifice-plate flowmeters yielded the most viable sensor pair combinations for all three volatile anesthetic gases in the study. Further testing is needed to ensure sensor fusion performance under conditions reflective of clinical use.
JOURNAL OF CLINICAL MONITORING AND COMPUTING
(2022)
Article
Medicine, General & Internal
Johannes Mueller, Walter Ploechl, Paul Muehlbacher, Alexandra Graf, Thomas Stimpfl, Thomas Hamp
Summary: The aim of this study was to investigate the effect of two different doses of pregabalin on the minimum alveolar concentration (MAC) of sevoflurane. The researchers found that a dose of 300mg pregabalin significantly reduced the MAC of sevoflurane, while a dose of 150mg had a less significant effect. Pregabalin use led to a slight reduction in post-operative pain levels but increased side effects as the dose increased.
FRONTIERS IN MEDICINE
(2022)
Article
Engineering, Environmental
Ushtar Arshad, Syed Ali Ammar Taqvi, Azizul Buang
Summary: Corn dust, a highly energetic substance, poses occupational safety hazards and explosion risks. The minimum ignition temperature is influenced by factors like particle size, concentration, and dispersion pressure. Experimental and statistical methods can effectively assess and predict the minimum ignition temperature to prevent explosion incidents.
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
(2021)
Article
Veterinary Sciences
Marcela L. Machado, Joao H. N. Soares, Bruno H. Pypendop, Natalia Henao-Guerrero, Renato L. S. Oliveira
Summary: The study found that fentanyl has a concentration-dependent effect on the minimum alveolar concentration of isoflurane, heart rate, and cardiac index. Additionally, it was observed that the prevention of fentanyl-induced bradycardia led to improvements in cardiovascular variables.
VETERINARY ANAESTHESIA AND ANALGESIA
(2022)
Review
Respiratory System
Jaime H. Jordan, Santiago Pedroza, Einar S. Billefals, Gustavo Cruz
Summary: Diffuse alveolar hemorrhage caused by sevoflurane inhalation is a rare condition that should be considered in postoperative patients presenting with symptoms such as hemoptysis, hypoxemia, or radiographic alveolar infiltrates. This case report presents a 42-year-old man who developed diffuse alveolar hemorrhage after sedation with sevoflurane during a low-risk orthopedic procedure. Early identification and management of this respiratory complication were crucial for a successful recovery.
RESPIRATORY MEDICINE CASE REPORTS
(2023)
Article
Veterinary Sciences
Cristina Orden, Martin Santos, Maria Ceprian, Francisco J. Tendillo
Summary: In rats, CBD administered alone did not reduce MAC(SEV), but the addition of morphine to different doses of CBD significantly reduced MAC(SEV).
VETERINARY ANAESTHESIA AND ANALGESIA
(2021)
Article
Veterinary Sciences
Reza Seddighi, Anthony Geist, Heather Knych, Xiaocun Sun
Summary: This study aimed to determine the effect of remifentanil infusion on the minimum alveolar concentration of sevoflurane preventing movement (SEVOMACNM) and bispectral index (BIS) in dogs. The results showed that remifentanil infusion significantly decreased SEVOMACNM, but had no effect on BIS.
VETERINARY ANAESTHESIA AND ANALGESIA
(2023)
Review
Surgery
Ryan Chadha, Dhupal Patel, Pooja Bhangui, Annabel Blasi, Victor Xia, Matteo Parotto, Christopher Wray, James Findlay, Michael Spiro, Dimitri Aristotle Raptis, Claus Niemann, Joerg-Matthias Pollok, Marina Berenguer, Pascale Tinguely, Ka Hay Fan, Giselle Farrer
Summary: In this systematic review, the impact of intraoperative anesthetic management on short-term outcomes following liver transplantation was discussed. The review found that there is no clear consensus in the literature regarding the effect of anesthetic management on short-term outcomes. The expert panel made several recommendations based on the available evidence.
CLINICAL TRANSPLANTATION
(2022)
Article
Geriatrics & Gerontology
Chengwei Yang, Fang Kang, Wenjun Meng, Meirong Dong, Xiang Huang, Sheng Wang, Zhiyi Zuo, Juan Li
Summary: This study compared the minimum alveolar concentration-awake (MAC(awake)) of sevoflurane in Parkinson's disease (PD) patients with non-PD patients, finding that PD patients had a significantly lower MAC(awake) and clinicians should avoid overdosing sevoflurane in PD patients.
CLINICAL INTERVENTIONS IN AGING
(2021)
Article
Veterinary Sciences
Rachel C. Hector, Marlis L. Rezende, Khursheed R. Mama, Eugene P. Steffey, Marja R. Raekallio, Outi M. Vainio
Summary: The study found that the combined use of vatinoxan and dexmedetomidine can significantly reduce the requirement for sevoflurane in dogs while also improving cardiovascular function. The addition of vatinoxan can attenuate the adverse effects of dexmedetomidine, such as slowing heart rate and decreasing CO, and gradually restore cardiovascular variables to baseline levels.
VETERINARY ANAESTHESIA AND ANALGESIA
(2021)
Article
Health Care Sciences & Services
Aram Mardian, Luzmercy Perez, Ting Pun, Matthias Cheung, Joel Porter, Korina De Bruyne, Ming-Chih Kao, Pamela Flood, Nathaniel Moore, Luana Colloca, Eric Cramer, Claire E. Ashton-James, Kate Lorig, Sean C. Mackey, Beth D. Darnall
Summary: Patients with chronic pain, especially those on long-term prescription opioids, often experience stigma in the healthcare system. Lack of data and poor opioid policies contribute to misconceptions and challenges in patient and clinician engagement. The complexity of opioid stewardship and research may also hinder clinicians from participating effectively.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Letter
Anesthesiology
Dennis M. Fisher, Steven L. Shafer
ANESTHESIA AND ANALGESIA
(2022)
Letter
Anesthesiology
Elizabeth B. Malinzak, Linda B. Hertzberg, Christine A. Doyle, Pamela Flood, Molly B. Kraus, Elizabeth Rebello, Sher-Lu Pai, Sonya Pease
ANESTHESIA AND ANALGESIA
(2022)
Editorial Material
Anesthesiology
Hugh C. Hemmings, Steven L. Shafer
BRITISH JOURNAL OF ANAESTHESIA
(2022)
Article
Anesthesiology
Jessica R. Ansari, Neil Kalariya, Brendan Carvalho, Pamela Flood, Nan Guo, Edward Riley
Summary: This study aimed to assess the feasibility, patient tolerance, pharmacokinetics, and potential effectiveness of intravenous calcium chloride for the prevention of uterine atony during cesarean delivery. The study found that intravenous calcium chloride was well-tolerated and may be effective in preventing uterine atony. Further large-scale clinical trials are warranted.
JOURNAL OF CLINICAL ANESTHESIA
(2022)
Article
Anesthesiology
Alexandra Ruan, Alexandra Klein, Preya Jhita, Natalya Hasan-Hill, Steven L. Shafer, Pamela D. Flood
Summary: Night float call systems are becoming increasingly common in training programs to reduce fatigue. Previous studies have shown decreased sleep and sleep efficiency during night float rotations. However, the impact on physical and emotional well-being has not been documented.
ANESTHESIA AND ANALGESIA
(2023)
Article
Public, Environmental & Occupational Health
Michelle Zhang, Corinne S. Cooley, Maisa Ziadni, Ian Mackey, Pamela Flood
Summary: Women who have given birth have a higher risk of experiencing functionally significant back pain. Severe acute postpartum back pain is a risk factor for future disability, indicating that the peripartum period may provide an important opportunity for intervention. Early recognition and management may mitigate future disability.
Letter
Anesthesiology
Alexandra Ruan, Pamela D. Flood
ANESTHESIA AND ANALGESIA
(2023)
Article
Anesthesiology
Cedar Fowler, Amy W. W. Chu, Nan Guo, Jessica R. Ansari, Steven L. Shafer, Pamela D. Flood
Summary: Most women who undergo cesarean delivery recover without complications. However, severe postoperative pain within the first few days is associated with increased risk of prolonged pain and opioid use. This study evaluated the effectiveness of outpatient treatment with gabapentin to facilitate opioid cessation in women with severe early onset pain after cesarean delivery.
ANESTHESIA AND ANALGESIA
(2023)
Meeting Abstract
Neurosciences
Carolyn Rodriguez, Chi-Ming Chen, Gary Glover, Booil Jo, Daniel Spielman, Leanne Williams, Peter van Roessel, Charles DeBattista, Pamela Flood, Alan Ringold, Max Wintermark, Kelley Anderson, Omer Linkovski, Anthony Lombardi, Andrea Millen, Anthony Pinto, Hannah Raila, Keara Valentine, Maria Filippou-Frye, Jessica Hawkins, Elizabeth McCarthy, Pavithra Mukunda, Andrea Varias, Jordan Wilson, Brianna Wright
NEUROPSYCHOPHARMACOLOGY
(2022)
Meeting Abstract
Cardiac & Cardiovascular Systems
Takamitsu Ikeda, Edilberto Amorim, Yusuke Miyazaki, Risako Kato, Eizo Marutani, Michael G. Silverman, Rajeev Malhotra, Ken Solt, Fumito Ichinose
Meeting Abstract
Anesthesiology
Risako Kato, Francisco Flores, Josefina Correa Menendez, Emery N. Brown, Ken Solt
ANESTHESIA AND ANALGESIA
(2022)
Meeting Abstract
Anesthesiology
Olivia Moody, Kathleen F. Vincent, Angel Cho, Risako Kato, Edlyn R. Zhang, Ken Solt
ANESTHESIA AND ANALGESIA
(2022)
Meeting Abstract
Anesthesiology
Alexandra Ruan, Alexandra Klein, Natalya Hasan, Pamela Flood
ANESTHESIA AND ANALGESIA
(2022)
Meeting Abstract
Anesthesiology
Kathleen F. Vincent, Angel Cho, Edlyn R. Zhang, Risako Kato, Olivia Moody, Ken Solt
ANESTHESIA AND ANALGESIA
(2022)