Article
Obstetrics & Gynecology
Dolores J. Lamb, Jessica A. Marinaro
Summary: Semen analysis plays an important role in the evaluation and management of infertility in men. Conventional semen analysis cannot reliably predict the chance of pregnancy or differentiate fertile vs. infertile men, and further research is needed to determine how to incorporate advanced, nonstandard sperm functional tests into clinical practice. Therefore, the primary applications of semen analysis are to assess the severity of infertility, estimate the effects of future therapy, and measure the response to current therapy.
FERTILITY AND STERILITY
(2023)
Article
Urology & Nephrology
Michael B. Tradewell, Jesse Ory, Daniel E. Nassau, Andrew H. Rezk, Emad Ibrahim, Ranjith Ramasamy
Summary: Men with a solitary testis have higher serum follicle-stimulating hormone levels and a higher prevalence of compensated hypogonadism compared to men with bilateral testes, indicating a pituitary strain. Further followup is needed to assess potential detrimental consequences of this compensated state on testicular function.
JOURNAL OF UROLOGY
(2021)
Article
Environmental Sciences
Saira Amir, Manolis Tzatzarakis, Charalampos Mamoulakis, Jaafar Haris Bello, Syed Ali Musstjab Akber Shah Eqani, Elena Vakonaki, Markos Karavitakis, Sikandar Sultan, Faheem Tahir, Syed Tahir Abbas Shah, Aristidis Tsatsakis
Summary: Male infertility is a major issue with various pathological factors such as endocrine disruption due to environmental pollution. Organochlorine pollutants can disrupt the male reproductive system, with PCBs, DDTs, and HCB being major concerns. Serum samples are the best for assessing health outcomes related to exposure levels.
ENVIRONMENTAL RESEARCH
(2021)
Review
Andrology
Ashok Agarwal, Rossella Cannarella, Ramadan Saleh, Florence Boitrelle, Murat Gul, Tuncay Toprak, Gianmaria Salvio, Mohamed Arafa, Giorgio I. Russo, Ahmed M. Harraz, Rajender Singh, Nicolas Garrido, Taha Abo-Almagd Abdel-Meguid Hamoda, Amarnath Rambhatla, Parviz Kavoussi, Shinnosuke Kuroda, Gokhan Calik, Pallavi Saini, Erman Ceyhan, Fotios Dimitriadis, Ralf Henkel, Andrea Crafa, Ayad Palani, Mesut Berkan Duran, Evangelos Maziotis, Emine Sais, Marion Bendayan, Mahsa Darbandi, Tan V. Le, Sezgin Gunes, Petroula Tsioulou, Pallav Sengupta, Berk Hazir, Gokhan Ceker, Sara Darbandi, Damayanthi Durairajanayagam, Azin Aghamajidi, Noora Alkhalidi, Emrullah Sogutdelen, Kristian Leisegang, Abdullah Alarbid, Christopher C. K. Ho, Vineet Malhotra, Federica Finocchi, Luis Crisostomo, Raghavender Kosgi, Haitham ElBardisi, Armand Zini, Ponco Birowo, Giovanni Colpi, Hyun Jun Park, Ege Can Serefoglu, Quang Nguyen, Edmund Ko, Jean de la Rosette, Germar M. Pinggera, Ho Vinh Phuoc Nguyen, Hussein Kandil, Rupin Shah
Summary: This study provides evidence for the positive effect of varicocele repair on conventional semen parameters in infertile men with clinical varicocele. There is significant improvement in sperm concentration, total motility, progressive motility, total sperm motility, and normal sperm morphology after varicocele repair. However, there is high inter-study heterogeneity.
WORLD JOURNAL OF MENS HEALTH
(2023)
Article
Obstetrics & Gynecology
Albert Salas-Huetos, Mariel Arvizu, Lidia Minguez-Alarcon, Makiko Mitsunami, Jordi Ribas-Maynou, Marc Yeste, Jennifer B. Ford, Irene Souter, Jorge E. Chavarro
Summary: This study found that women's consumption of omega-3 fatty acids and omega-3-rich foods may improve the probability of conception by decreasing the risk of pregnancy loss. Additionally, men's intake of omega-3 fatty acids may influence semen quality.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Review
Pharmacology & Pharmacy
Hye Won Lee, Myeong Soo Lee, Fan Qu, Je-Won Lee, Eunseop Kim
Summary: This study analyzed multiple studies and found that the use of maca for improving semen quality is still inconclusive, both for men experiencing infertility and healthy men. However, due to the limited number of studies and sample size, firm conclusions cannot be drawn.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Urology & Nephrology
Daniel R. Greenberg, Hriday P. Bhambhvani, Satvir S. Basran, Brett P. Salazar, Luis Carl Rios, Sin-Jin Li, Che-Hong Chen, Daria Mochly-Rosen, Michael L. Eisenberg
Summary: This study found an association between alcohol intake and semen parameters among East Asian men carrying the ALDH2*2 allele. Alcohol consumption was associated with significantly lower total and progressive sperm motility in ALDH2*2 carriers. Furthermore, ALDH2 expression in spermatozoa was significantly lower in ALDH2*2 carriers.
JOURNAL OF UROLOGY
(2022)
Article
Endocrinology & Metabolism
Hana Jaworek, Vladimira Koudelakova, Ivana Oborna, Blazena Zborilova, Jana Brezinova, Dagmar Ruzickova, Jana Vrbkova, Pavla Kourilova, Marian Hajduch
Summary: The study found that HPV infection is common in both potential sperm donors and men from infertile couples. HPV infection in semen samples affects sperm parameters, while there is no association between HPV positivity in semen and fertility outcomes.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2021)
Article
Obstetrics & Gynecology
Ido Feferkorn, Liat Azani, Einav Kadour-Peero, Ranit Hizkiyahu, Guy Shrem, Mali Salmon-Divon, Michael H. Dahan
Summary: Significant geographic variations in sperm parameters were found in this study, suggesting the importance of considering regional reference ranges based on local experience and treatment outcomes.
FERTILITY AND STERILITY
(2022)
Article
Medicine, General & Internal
Rune Holt, Sam Kafai Yahyavi, Ireen Kooij, Christine Hjorth Andreassen, Anna-Maria Andersson, Anders Juul, Niels Jorgensen, Martin Blomberg Jensen
Summary: This study investigated the role of circulating AMH in men and found that low serum AMH is associated with severely impaired gonadal function. Vitamin D supplementation had no effect on serum AMH.
Article
Medicine, General & Internal
Mousa Asadi, Farshad Gholipour, Amirhossein Rahavian, Mohammad Javanbakht
Summary: This study demonstrates that short-term use of probiotics after varicocelectomy can improve semen parameters. Although there were no significant differences in semen volume and sperm motility improvement, the probiotic group showed significant differences in sperm concentration and percentage of sperms with normal morphology.
JOURNAL OF RESEARCH IN MEDICAL SCIENCES
(2023)
Review
Food Science & Technology
Javad Heshmati
Summary: This study investigated the effects of omega-3 fatty acid supplementation on gene expression related to metabolic factors. The results suggest that omega-3 FA intake may improve gene expression of PPAR-gamma, while down-regulating LDLR and IL-1 gene expression.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Obstetrics & Gynecology
J. Stanhiser, A. M. Z. Jukic, D. R. McConnaughey, A. Z. Steiner
Summary: The study found that self-reported use of omega-3 fatty acid supplements was associated with an increased probability of conceiving.
HUMAN REPRODUCTION
(2022)
Article
Public, Environmental & Occupational Health
Marco Reschini, Luca Pagliardini, Luca Boeri, Francesca Piazzini, Veronica Bandini, Gianfranco Fornelli, Carolina Dolci, Greta Chiara Cermisoni, Paola Vigano, Edgardo Somigliana, Maria Elisabetta Coccia, Enrico Papaleo
Summary: This study examined the impact of COVID-19 vaccination on male reproductive health by assessing semen parameters and fertilization rate before and after vaccination. The results indicate that the vaccine does not affect sperm quality and fertilization capacity of men undergoing ART treatments.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Endocrinology & Metabolism
Bing Song, Yujie Chen, Chao Wang, Guanjian Li, Zhaolian Wei, Xiaojin He, Yunxia Cao
Summary: This study suggests that abnormal DNA methylation of certain CpG sites of imprinted genes is associated with poor sperm quality and severe sperm DNA damage.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2022)