Article
Chemistry, Multidisciplinary
Paula M. Castillo, Francisco J. Fernandez-Acejo, Jose M. Carnerero, Rafael Prado-Gotor, Aila Jimenez-Ruiz
Summary: The study utilizes the stabilizing effect of lysozymes to develop a quick naked-eye test for detecting urinary lysozyme concentrations over 57.2 μg/mL. By calculating color difference parameters, the test can reliably provide a positive colorimetric response in less than 15 minutes, making it useful for detecting disorders such as leukemia-associated lysozymurias.
Article
Chemistry, Analytical
Zeeshan A. Khan, Seungkyung Park
Summary: In this study, a colorimetric assay based on the binding of Aβ(1-40) to gold nanoparticles and metal ions was proposed for the detection of Aβ. This newly developed assay showed good linearity and high sensitivity for the detection of Aβ(1-40) in biological or biomedical samples.
Article
Chemistry, Multidisciplinary
Yiqian Su, Hongjiao Wu, Jiaqi Chen, Huiqin Li, Pengcheng Lin, Wei Xiao, Donglin Cao
Summary: A novel scandium-MOF nanozyme with peroxidase-like characteristics has been synthesized and used to develop an efficient biosensor for ascorbic acid (AA) detection. The biosensor exhibits superior specificity and anti-interference features, and can be applied to qualitative and quantitative AA detection in human serum.
Article
Chemistry, Analytical
Cheng Chen, Jing Li, Fang Luo, Zhenyu Lin, Jian Wang, Tao Zhang, Aiwen Huang, Bin Qiu
Summary: In this study, a Eu MOF was used to encapsulate FeNCDs, resulting in increased dispersibility and enzymatic catalytic efficiency. The FeNCDs@Eu MOF-based sensor exhibited a nearly 6-fold increase in response to tetracycline, with a low detection limit of 11.63 nM.
Article
Spectroscopy
Shuyan Xiao, Jiping Lu, Liang Sun, Shengli An
Summary: A new colorimetric biosensor for specific detection of azlocillin was developed using DNA aptamer and unmodified gold nanoparticles. The biosensor showed a red solution in the absence of azlocillin and a color change from red to blue in the presence of azlocillin. The biosensor exhibited a linear relationship with a detection limit of 11.6 nM and was successfully used to detect azlocillin in milk and tap water samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Spectroscopy
Munazza Arain, Ayman Nafady, Muhammad Anwar Ul Haq, Hafiz Muhammad Asif, Hafiz Badaruddin Ahmad, Muhammad Ali Khan, Saghir Hussain
Summary: Pesticides and fungicides are important for protecting crops, but they pose potential health risks. This study synthesized silver nanoparticles that can be used to detect the concentration of a specific fungicide. The nanoparticles were characterized using various techniques and their high sensitivity and selectivity were confirmed.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Food Science & Technology
Xiangyu Song, Huhu Wang, Xinglian Xu
Summary: In this study, a novel biosensing strategy for bacterial sensing based on modified gold nanoparticles (AuNPs) combined with amikacin as the molecular recognition element is proposed. The biosensor shows a good linear correlation with bacterial concentration and can detect bacteria within a short period of time without the need for expensive reagents or complex instruments.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Applied
Jingwen Li, Yongming Liu, Hao Lin, Yan Chen, Zhenbo Liu, Xuming Zhuang, Chunyuan Tian, Xiuli Fu, Lingxin Chen
Summary: A label-free colorimetric method based on Exo I-assisted signal amplification with protamine as a medium was developed for analysis of kanamycin. The method, which involved manipulating a dsDNA probe tailored from an aptamer and cDNA, demonstrated high selectivity and sensitivity for target detection. The strategy showed great potential for fabricating various biosensors based on target-induced aptamer configuration changes.
Article
Chemistry, Analytical
Shengda Qi, Haitham Saad Al-mashriqi, Abdulwahab Salah, Honglin Zhai
Summary: In this study, a novel method for detecting transferrin based on GSH-AuNCs was developed for the first time, showing high selectivity and sensitivity. The proposed method has been successfully applied for the determination of transferrin in rat serum samples.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Maurice Retout, Bryan Gosselin, Alice Mattiuzzi, Indiana Ternad, Ivan Jabin, Gilles Bruylants
Summary: In this study, a biosensor based on silver nanoparticles functionalized by peptide aptamers was developed for the detection of the Mdm2 protein. Results showed that replacing gold nanoparticles with silver nanoparticles improved the detection limit and provided high selectivity and stability.
Article
Chemistry, Multidisciplinary
Huiqin Li, Hongjiao Wu, Jiaqi Chen, Yiqian Su, Pengcheng Lin, Wei Xiao, Donglin Cao
Summary: In this study, a GSH colorimetric sensor based on an iron-copper MOF with peroxidase-like properties was developed. The sensor converts hydrogen peroxide to hydroxyl radicals and catalyzes the oxidation of TMB, allowing quantification of GSH content in human serum.
Article
Chemistry, Analytical
Fan Li, Tianshuang He, Sihao Wu, Zoujun Peng, Ping Qiu, Xiaomin Tang
Summary: The study developed a novel uric acid detection method using chitosan stabilized gold nanoparticles, which showed high sensitivity and simplicity. The method was successfully applied to human serum and urine samples with high recovery rates, indicating its potential as an alternative for clinical medicine and daily monitoring.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Yuanshang Wang, Xiaoran Wang, Yi Yan, Jia Wang, Youyou Lu, A. M. Abd El-Aty, Xiaohong Wang
Summary: A new technique utilizing phage T156-mediated aggregation of gold nanoparticles was developed for visual and precise detection of Salmonella. The method offers simplicity, speed, and the ability to distinguish between live and dead Salmonella, demonstrating remarkable sensitivity, specificity, and accuracy. It also presents a novel avenue for the rapid detection of other pathogenic bacteria.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Physical
Daniel Boas, Sergei Remennik, Meital Reches
Summary: We have developed a short peptide consisting of only six amino acids that can simultaneously reduce Au3+ or Ag+ ions and stabilize the resulting nanoparticles. The peptide-capped nanoparticles demonstrated a fast, selective, and pH-dependent detection system for Hg2+, Mn2+, and Fe2+ ions. In addition, the peptide-mediated photoreduction process successfully enveloped gold nanoparticles with a silver shell, resulting in bimetallic Au@Ag core/shell nanoparticles.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Engineering, Environmental
Titilope John Jayeoye, Jie Ma, Thitima Rujiralai
Summary: A sensitive and selective colorimetric assay for silver ion detection was demonstrated using creatinine assembled on dithiobis(succinimidylpropionate) modified gold nanoparticles as an optical probe. The method showed high accuracy and precision in detecting Ag+ in water samples, with a detection limit far below the acceptable limit set by USEPA. The aggregation of nanoparticles led to a color change from red to blue-grey, providing a visual indication of Ag+ presence.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Chemistry, Analytical
Gang Qu, Yuxin Zhao, Qiaoli Zhang, Jina Wu, Xiaosen Li, Yang Yang, Shilei Liu
Summary: In this study, magnetic mesoporous materials combined with real-time in situ mass spectrometry were used for the high-throughput detection of hydrolyzed products of organophosphorus nerve agents. The method showed good linearity, low limits of detection and quantification, and high extraction recoveries. The magnetic preparation method used was quick, cost-effective, rugged, and safe. The results demonstrated the potential of this method for rapid and efficient determination of the target analytes in environmental samples.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Anna Hildebrand, Mariam Merchant, Danny O'Hare
Summary: Substandard and falsified artemisinin derivatives in antimalarials have caused significant deaths and economic losses. This study evaluates the feasibility of voltammetric methods for identifying and quantifying artemether. The findings suggest that electrochemical analysis shows promise as a method for artemether identification and quantification.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Marx Osorio Araujo Pereira, Alvaro Ferreira Junior, Edson Silvio Batista Rodrigues, Helena Mulser, Giovanna Nascimento de Mello e Silva, Wallans Torres Pio dos Santos, Eric de Souza Gil
Summary: Brazilian spotted fever (BSF) is a serious and rapidly evolving disease. A new impedimetric immunosensor was developed for rapid diagnosis by measuring specific antibodies in plasma. The sensor demonstrated selectivity and accuracy, and has potential for important applications in diagnostic testing.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Kathrin Schilling, Ronald A. Glabonjat, Olgica Balac, Marta Galvez-Fernandez, Arce Domingo-Relloso, Vesna Slavkovich, Jeff Goldsmith, Miranda R. Jones, Tiffany R. Sanchez, Ana Navas-Acien
Summary: Analysis of trace elements in urine is an important tool for assessing exposures, diagnosing nutritional status, and guiding public health and healthcare intervention. This study provides a sensitive method for analyzing 18 elements in urine samples, using only 100 μL. The results show good accuracy and sensitivity of the method.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Mengya Li, Shijie Liu, Shiliang Guo, Dong Liang, Miaoyun Li, Yaodi Zhu, Lijun Zhao, Jong-Hoon Lee, Gaiming Zhao, Yangyang Ma, Yanxia Liu
Summary: In this study, a magnetic flow device was developed to purify spores in a culture medium system. The device used magnetic nanoparticles to absorb vegetative cells, separating them from the spores. The achieved purity of the collected spores was over 95%. The study also demonstrated a rapid quantitative detection method using Raman spectroscopy.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Wanqiong Liu, Zixuan Wu, Jianwei Peng, Zebin Xu, Yong Liang
Summary: Metal-organic frameworks (MOFs) are effective carriers for molecular imprinting, but their poor dispersibility in aqueous solution is a significant drawback. In this study, we have applied amphiphilic block copolymers and molecularly imprinted technology on MOFs to improve the hydrophilicity of molecularly imprinted fluorescent materials.
ANALYTICAL METHODS
(2024)