Experimental Evidence Shows Salubrinal, an eIF2α Dephosphorylation Inhibitor, Reduces Xenotoxicant-Induced Cellular Damage

Autophagy protects renal tubular cells against cyclosporine toxicity

(2014) Nicolas Pallet et al.   Autophagy

Salubrinal protects against rotenone-induced SH-SY5Y cell death via ATF4-parkin pathway

(2014) Liang Wu et al.   BRAIN RESEARCH

Therapeutical Effects and Mechanism of Salubrinal Combined with Ulinastatin on Treating Paraquat Poisoning

(2014) Hua Guo et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Salubrinal, ER stress inhibitor, attenuates kainic acid-induced hippocampal cell death

(2014) Jung Soo Kim et al.   JOURNAL OF NEURAL TRANSMISSION

Endoplasmic Reticulum Stress Plays a Key Role in Rotenone-Induced Apoptotic Death of Neurons

(2014) Poonam Goswami et al.   MOLECULAR NEUROBIOLOGY

The PERK-eIF2α signaling pathway is involved in TCDD-induced ER stress in PC12 cells

(2014) Zhiqing Duan et al.   NEUROTOXICOLOGY

Arsenic trioxide induces unfolded protein response in vascular endothelial cells

(2013) Ching-Yi Weng et al.   ARCHIVES OF TOXICOLOGY

Regulatory crosstalk within the mammalian unfolded protein response

(2013) Joseph W. Brewer   CELLULAR AND MOLECULAR LIFE SCIENCES

Salubrinal reduces expression and activity of MMP13 in chondrocytes

(2013) K. Hamamura et al.   OSTEOARTHRITIS AND CARTILAGE

The unfolded protein response triggered by environmental factors

(2013) Masanori Kitamura   Seminars in Immunopathology

Salubrinal Protects Against Cigarette Smoke Extract-induced HBEpC Apoptosis Likely Via Regulating the Activity of PERK-eIF2α Signaling Pathway

(2012) Ting Yuan et al.   ARCHIVES OF MEDICAL RESEARCH

Endoplasmic reticulum (ER) stress inhibitor salubrinal protects against ceramide-induced SH-SY5Y cell death

(2012) Ting Gong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The impact of the unfolded protein response on human disease

(2012) Shiyu Wang et al.   JOURNAL OF CELL BIOLOGY

Endoplasmic Reticulum Stress Is Important for the Manifestations of  -Synucleinopathy In Vivo

(2012) E. Colla et al.   JOURNAL OF NEUROSCIENCE

Endoplasmic reticulum stress modulates nicotine-induced extracellular matrix degradation in human periodontal ligament cells

(2012) S.-I. Lee et al.   JOURNAL OF PERIODONTAL RESEARCH

Effects of salubrinal on cadmium-induced apoptosis in HK-2 human renal proximal tubular cells

(2011) Yuta Komoike et al.   ARCHIVES OF TOXICOLOGY

Salubrinal, an eIF2α dephosphorylation inhibitor, enhances cisplatin-induced oxidative stress and nephrotoxicity in a mouse model

(2011) Cheng Tien Wu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Critical role of proteostasis-imbalance in pathogenesis of COPD and severe emphysema

(2011) Taehong Min et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Salubrinal attenuates β-amyloid-induced neuronal death and microglial activation by inhibition of the NF-κB pathway

(2011) Xiumei Huang et al.   NEUROBIOLOGY OF AGING

The oxidative stress: endoplasmic reticulum stress axis in cadmium toxicity

(2010) Masanori Kitamura et al.   BIOMETALS

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Amyloid β-induced FOXRED2 mediates neuronal cell death via inhibition of proteasome activity

(2010) SangMi Shim et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Endoplasmic reticulum stress as a progression factor for kidney injury

(2010) Reiko Inagi   CURRENT OPINION IN PHARMACOLOGY

Phosphorylation of the α-subunit of the eukaryotic initiation factor-2 (eIF2α) alleviates benzo[a]pyrene-7,8-diol-9,10-epoxide induced cell cycle arrest and apoptosis in human cells

(2010) Qiaoling Wang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Activation of PERK Signaling Attenuates Aβ-Mediated ER Stress

(2010) Do Yeon Lee et al.   PLoS One

The Role of Endoplasmic Reticulum Stress–Related Unfolded Protein Response in the Radiocontrast Medium–Induced Renal Tubular Cell Injury

(2010) Cheng T. Wu et al.   TOXICOLOGICAL SCIENCES

ASK1 Overexpression Accelerates Paraquat-Induced Autophagy via Endoplasmic Reticulum Stress

(2010) Mireia Niso-Santano et al.   TOXICOLOGICAL SCIENCES

Paraquat activates the IRE1/ASK1/JNK cascade associated with apoptosis in human neuroblastoma SH-SY5Y cells

(2009) Wonsuk Yang et al.   TOXICOLOGY LETTERS

Cyclosporine-Induced Endoplasmic Reticulum Stress Triggers Tubular Phenotypic Changes and Death

(2008) N. Pallet et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins

(2008) Sami Reijonen et al.   EXPERIMENTAL CELL RESEARCH

Basal Levels of eIF2α Phosphorylation Determine Cellular Antioxidant Status by Regulating ATF4 and xCT Expression

(2008) Jan Lewerenz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arsenite-induced cytotoxicity in dorsal root ganglion explants

(2007) Y.H. Chou et al.   FREE RADICAL BIOLOGY AND MEDICINE

Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells

(2007) Yeo Kyoung Oh et al.   JOURNAL OF NEUROCHEMISTRY